KR900007950B1 - 모노클로날 항체의 제조방법 - Google Patents

모노클로날 항체의 제조방법 Download PDF

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Publication number
KR900007950B1
KR900007950B1 KR1019860003999A KR860003999A KR900007950B1 KR 900007950 B1 KR900007950 B1 KR 900007950B1 KR 1019860003999 A KR1019860003999 A KR 1019860003999A KR 860003999 A KR860003999 A KR 860003999A KR 900007950 B1 KR900007950 B1 KR 900007950B1
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KR
South Korea
Prior art keywords
cells
human
cell line
hybridoma
monkey
Prior art date
Application number
KR1019860003999A
Other languages
English (en)
Korean (ko)
Other versions
KR860009125A (ko
Inventor
군나르 오스트베르그 라르스
Original Assignee
산도즈 파마슈티칼스 코포레이션
게랄드 디. 샤르킨
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 산도즈 파마슈티칼스 코포레이션, 게랄드 디. 샤르킨 filed Critical 산도즈 파마슈티칼스 코포레이션
Publication of KR860009125A publication Critical patent/KR860009125A/ko
Application granted granted Critical
Publication of KR900007950B1 publication Critical patent/KR900007950B1/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C12N5/166—Animal cells resulting from interspecies fusion

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
KR1019860003999A 1985-05-23 1986-05-22 모노클로날 항체의 제조방법 KR900007950B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73719685A 1985-05-23 1985-05-23
US737196 1985-05-23

Publications (2)

Publication Number Publication Date
KR860009125A KR860009125A (ko) 1986-12-20
KR900007950B1 true KR900007950B1 (ko) 1990-10-23

Family

ID=24962960

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019860003999A KR900007950B1 (ko) 1985-05-23 1986-05-22 모노클로날 항체의 제조방법

Country Status (22)

Country Link
JP (2) JPS61271982A (tr)
KR (1) KR900007950B1 (tr)
AT (1) AT396936B (tr)
AU (1) AU603985B2 (tr)
BE (1) BE904811A (tr)
CH (1) CH670098B (tr)
CY (1) CY1644A (tr)
DE (1) DE3616324C2 (tr)
DK (1) DK240286A (tr)
FI (1) FI93469C (tr)
FR (1) FR2587357B1 (tr)
GB (1) GB2175918B (tr)
HK (1) HK37792A (tr)
IE (1) IE59184B1 (tr)
IL (1) IL78871A (tr)
IT (1) IT1203789B (tr)
LU (1) LU86437A1 (tr)
NL (1) NL8601263A (tr)
NZ (1) NZ216251A (tr)
SE (1) SE8602288L (tr)
SG (1) SG32392G (tr)
ZA (1) ZA863871B (tr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646041A (en) * 1987-02-12 1997-07-08 Harfeldt; Elisabeth Monoclonal antibody to herpes simplex virus and cell line producing same
IT1226477B (it) * 1988-07-04 1991-01-16 Genetik Mab S R L Linee cellulari n omas quale un mezzo per immortalare cellule produttrici di sostanze di qualunque specie animale.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4381292A (en) * 1980-11-14 1983-04-26 The Board Of Trustees Of The Leland Stanford Jr. University Anti-human T-lymphocyte monoclonal antibody
US4474893A (en) * 1981-07-01 1984-10-02 The University of Texas System Cancer Center Recombinant monoclonal antibodies
CH652145A5 (de) * 1982-01-22 1985-10-31 Sandoz Ag Verfahren zur in vitro-herstellung von hybridomen welche humane monoklonale antikoerper erzeugen.
DE3330160A1 (de) * 1983-08-20 1985-03-07 Boehringer Ingelheim KG, 6507 Ingelheim Monoklonaler antikoerper mit hoher affinitaet zum digoxin
US4777245A (en) * 1984-01-06 1988-10-11 Genelabs Incorporated Non-human primate monoclonal antibodies and methods
US4746612A (en) * 1984-10-12 1988-05-24 Scripps Clinic & Research Foundation Aotus interspecies hybridomas and monoclonal receptors produced thereby

Also Published As

Publication number Publication date
IL78871A (en) 1991-06-30
FI862131A (fi) 1986-11-24
ATA135886A (de) 1993-05-15
LU86437A1 (fr) 1986-12-02
GB8612160D0 (en) 1986-06-25
NZ216251A (en) 1989-11-28
FI93469B (fi) 1994-12-30
AT396936B (de) 1993-12-27
SE8602288D0 (sv) 1986-05-21
KR860009125A (ko) 1986-12-20
AU603985B2 (en) 1990-12-06
JPH0841100A (ja) 1996-02-13
AU5764086A (en) 1986-11-27
FR2587357A1 (fr) 1987-03-20
ZA863871B (en) 1988-01-27
GB2175918A (en) 1986-12-10
GB2175918B (en) 1989-06-28
CH670098B (tr) 1989-05-12
BE904811A (fr) 1986-11-24
JPS61271982A (ja) 1986-12-02
IT8648048A0 (it) 1986-05-23
DK240286D0 (da) 1986-05-22
IE59184B1 (en) 1994-01-26
FR2587357B1 (fr) 1989-10-27
IT1203789B (it) 1989-02-23
DK240286A (da) 1986-11-24
FI862131A0 (fi) 1986-05-21
CY1644A (en) 1992-11-06
SG32392G (en) 1992-05-15
IL78871A0 (en) 1986-09-30
NL8601263A (nl) 1986-12-16
FI93469C (fi) 1995-04-10
IE861347L (en) 1986-11-23
DE3616324C2 (de) 1995-03-09
DE3616324A1 (de) 1986-11-27
SE8602288L (sv) 1986-11-24
HK37792A (en) 1992-06-04

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