KR890701587A - 골 손실에 관련된 질병 치료용 이미다조(1,2-a)(피리 - Google Patents

골 손실에 관련된 질병 치료용 이미다조(1,2-a)(피리

Info

Publication number
KR890701587A
KR890701587A KR1019890701209A KR890701209A KR890701587A KR 890701587 A KR890701587 A KR 890701587A KR 1019890701209 A KR1019890701209 A KR 1019890701209A KR 890701209 A KR890701209 A KR 890701209A KR 890701587 A KR890701587 A KR 890701587A
Authority
KR
South Korea
Prior art keywords
compound
formula
lower alkyl
treatment
alkyl
Prior art date
Application number
KR1019890701209A
Other languages
English (en)
Korean (ko)
Inventor
스타르케 인게마르
발마르크 뵈외른
베네넨 칼레르보
Original Assignee
앤더스 베딘
악티에볼라게트 헤슬레
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 앤더스 베딘, 악티에볼라게트 헤슬레 filed Critical 앤더스 베딘
Publication of KR890701587A publication Critical patent/KR890701587A/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1019890701209A 1987-10-30 1988-10-27 골 손실에 관련된 질병 치료용 이미다조(1,2-a)(피리 KR890701587A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE8704248-7 1987-10-30
SE8704248A SE8704248D0 (sv) 1987-10-30 1987-10-30 Medical use
PCT/SE1988/000576 WO1989003833A1 (fr) 1987-10-30 1988-10-27 IMIDAZO(1,2-a)(PYRIDAZINES OU PYRAZINES) PERMETTANT LE TRAITEMENT DE MALADIES RELATIVES A LA PERTE OSSEUSE

Publications (1)

Publication Number Publication Date
KR890701587A true KR890701587A (ko) 1989-12-21

Family

ID=20370069

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019890701209A KR890701587A (ko) 1987-10-30 1988-10-27 골 손실에 관련된 질병 치료용 이미다조(1,2-a)(피리

Country Status (9)

Country Link
EP (1) EP0339071A1 (fr)
JP (1) JPH02501929A (fr)
KR (1) KR890701587A (fr)
AU (1) AU2620388A (fr)
DK (1) DK322189D0 (fr)
HU (1) HU203663B (fr)
IL (1) IL88205A0 (fr)
SE (1) SE8704248D0 (fr)
WO (1) WO1989003833A1 (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT87988B (pt) * 1987-07-16 1995-05-04 Byk Gulden Lomberg Chem Fab Processo para a preparacao de diazois e de composicoes farmaceuticas que os contem
US5081253A (en) * 1989-12-21 1992-01-14 American Home Products Corporation Imidazo(4,5-c)pyridines as antiosteoporotic agents
US5464843A (en) * 1992-06-23 1995-11-07 G.D. Searle & Co. Imidazo[1,2-a]pyridinyldiacid compounds for cognitive enhancement and for treatment of cognitive disorders and neutrotoxic injury
AU5348396A (en) * 1995-05-01 1996-11-21 Fujisawa Pharmaceutical Co., Ltd. Imidazo 1,2-a pyridine and imidazo 1,2-a pyridezine derivati ves and their use as bone resorption inhibitors
GB9518552D0 (en) * 1995-09-11 1995-11-08 Fujisawa Pharmaceutical Co New heterocyclic compounds
US7709468B2 (en) 2005-09-02 2010-05-04 Abbott Laboratories Imidazo based heterocycles
EP2655362A1 (fr) 2010-12-22 2013-10-30 Abbvie Inc. Inhibiteurs de l'hépatite c et leurs utilisations
DE102012200349A1 (de) 2012-01-11 2013-07-11 Bayer Intellectual Property Gmbh Substituierte annellierte Pyrimidine und Triazine und ihre Verwendung
US8778964B2 (en) 2012-11-05 2014-07-15 Bayer Pharma Aktiengesellschaft Hydroxy-substituted imidazo[1,2-a]-pyridinecarboxamides and their use
US9624214B2 (en) 2012-11-05 2017-04-18 Bayer Pharma Aktiengesellschaft Amino-substituted imidazo[1,2-a]pyridinecarboxamides and their use
US8796305B2 (en) 2012-11-05 2014-08-05 Bayer Pharma Aktiengesellschaft Carboxy-substituted imidazo[1,2-a]pyridinecarboxamides and their use
US9126998B2 (en) 2012-11-05 2015-09-08 Bayer Pharma AG Amino-substituted imidazo[1,2-a]pyridinecarboxamides and their use
CN105339368B (zh) 2013-06-04 2017-08-15 拜耳制药股份公司 3‑芳基‑取代的咪唑并[1,2‑a]吡啶及其用途
WO2015004105A1 (fr) 2013-07-10 2015-01-15 Bayer Pharma Aktiengesellschaft Benzyl-1h-pyrazolo[3,4-b]pyridine et utilisation de cette dernière
CN106459090A (zh) 2014-02-19 2017-02-22 拜耳制药股份公司 3‑(嘧啶‑2‑基)咪唑并[1,2‑a]吡啶
EP3119777A1 (fr) 2014-03-21 2017-01-25 Bayer Pharma Aktiengesellschaft Imidazo[1,2-a]pyridine-carboxamides cyano-substitués et leur utilisation
CA2947372A1 (fr) * 2014-05-02 2015-11-05 Bayer Pharma Aktiengesellschaft Imidazo[1,2-a]pyridine carboxamides substitues par chlore en position 6 et leur utilisation en tant que stimulateurs de la guanylate cyclase soluble
US20170050962A1 (en) * 2014-05-02 2017-02-23 Bayer Pharma Aktiengesellschaft Imidazo[1,2-a]pyridines as stimulators of soluble guanylate cyclase for treating cardiovascular diseases
WO2015165930A1 (fr) 2014-05-02 2015-11-05 Bayer Pharma Aktiengesellschaft Énantiomères du n-(2-amino-5-fluor-2-méthylpentyl)-8-[(2,6-difluorbenzyl)oxy]-2-méthylimidazo[1,2-a]pyridine-3-carboxamide et de ses dérivés difluorés et trifluorés pour traiter des maladies cardiovasculaires
WO2016087343A1 (fr) 2014-12-02 2016-06-09 Bayer Pharma Aktiengesellschaft Imidazo[1,2-a]pyridines à substitution hétéroaryle et leur utilisation
WO2016087342A1 (fr) 2014-12-02 2016-06-09 Bayer Pharma Aktiengesellschaft Pyrazolo[1,5-a]pyridines et imidazo[1,2-a]pyrazines substituées et leur utilisation
EP3286185A1 (fr) 2015-02-05 2018-02-28 Bayer Pharma Aktiengesellschaft Pyrazolo[1,5-a]pyridine-3-carboxamides substitués et leur utilisation
WO2016124564A1 (fr) 2015-02-05 2016-08-11 Bayer Pharma Aktiengesellschaft Dérivés de 8-[(2,6-difluorobenzyl)oxy]-2,6-diméthylimidazo[1,2-a]pyrazine-3-carboxamide n-substitués utilisés comme stimulateurs de la guanylate cyclase soluble (sgc) pour traiter des maladies cardiovasculaires
WO2018184976A1 (fr) 2017-04-05 2018-10-11 Bayer Pharma Aktiengesellschaft Imidazo[1,2-a]pyridine-carboxamides substitués et leur utilisation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0068378B1 (fr) * 1981-06-26 1986-03-05 Schering Corporation Imidazo(1,2-a)pyridines et pyrazines, procédés pour leur préparation et composés pharmaceutiques les contenant
US4468400A (en) * 1982-12-20 1984-08-28 Schering Corporation Antiulcer tricyclic imidazo [1,2-a]pyridines
DE3446778A1 (de) * 1984-12-21 1986-07-03 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazoderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel
US4725601A (en) * 1985-06-04 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers
EP0228006A1 (fr) * 1985-12-16 1987-07-08 Fujisawa Pharmaceutical Co., Ltd. Composés d'imidazopyridine et procédés pour leur préparation

Also Published As

Publication number Publication date
SE8704248D0 (sv) 1987-10-30
DK322189A (da) 1989-06-28
HUT51138A (en) 1990-04-28
WO1989003833A1 (fr) 1989-05-05
HU203663B (en) 1991-09-30
JPH02501929A (ja) 1990-06-28
AU2620388A (en) 1989-05-23
EP0339071A1 (fr) 1989-11-02
IL88205A0 (en) 1989-06-30
DK322189D0 (da) 1989-06-28

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