KR890015752A - 항-cpbii 모노클로날 항체 - Google Patents

항-cpbii 모노클로날 항체 Download PDF

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Publication number
KR890015752A
KR890015752A KR1019890004560A KR890004560A KR890015752A KR 890015752 A KR890015752 A KR 890015752A KR 1019890004560 A KR1019890004560 A KR 1019890004560A KR 890004560 A KR890004560 A KR 890004560A KR 890015752 A KR890015752 A KR 890015752A
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KR
South Korea
Prior art keywords
cpbii
coagulation inhibitor
monoclonal antibodies
monoclonal antibody
human placenta
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KR1019890004560A
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English (en)
Inventor
타카오 나고야
유끼오 하또리
Original Assignee
미와 다까야수
코와 가부시끼 가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 미와 다까야수, 코와 가부시끼 가이샤 filed Critical 미와 다까야수
Publication of KR890015752A publication Critical patent/KR890015752A/ko

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/50Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Developmental Biology & Embryology (AREA)
  • Genetics & Genomics (AREA)
  • Reproductive Health (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pregnancy & Childbirth (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gynecology & Obstetrics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)

Abstract

내용 없음

Description

항-CPBII 모노클로날 항체
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제 1 도는 CPBII-A29가 코팅모노클로날 항체로 사용된 반면, CPBII-A511이 콘쥬게이트되는 모노클로날 항체로 사용되는 실시예 4중 CPBII의 검정에서 CPBII 농도와 흡광도(492nm) 사이의 관계를 나타내는 도면.

Claims (4)

  1. 사람태반 유래 응고 억제제 CPBII에 특이적인 모노클로날항체.
  2. 사람태반 유래 응고 억제제 CPBII에 특이적인 모노클로날 항체를 분비하는 하이브리도마.
  3. 사람태반 유래 응고 억제제 CPBII에 특이적인 모노클로날 항체를 면역 흡착제로서 사용함을 특징으로 하는 사람태반 유래 응고 억제제 CPBII의 정제방법.
  4. 사람태반 유래 응고 억제제 CPBII에 특이적인 모노클로날 항체의 콘쥬게이트를 사용함을 특징으로 하는 사람태반 유래 응고억제제 CPBII의 면역검정.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019890004560A 1988-04-08 1989-04-06 항-cpbii 모노클로날 항체 KR890015752A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP63086753A JP2639684B2 (ja) 1988-04-08 1988-04-08 抗cpb▲ii▼モノクローナル抗体
JP63-86753 1988-04-08

Publications (1)

Publication Number Publication Date
KR890015752A true KR890015752A (ko) 1989-11-25

Family

ID=13895523

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019890004560A KR890015752A (ko) 1988-04-08 1989-04-06 항-cpbii 모노클로날 항체

Country Status (6)

Country Link
EP (1) EP0336441B1 (ko)
JP (1) JP2639684B2 (ko)
KR (1) KR890015752A (ko)
CA (1) CA1335355C (ko)
DE (1) DE68916088T2 (ko)
ES (1) ES2056995T3 (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4012341A1 (de) * 1990-04-18 1991-10-24 Behringwerke Ag Monoklonale antikoerper gegen pp4, verfahren zu ihrer herstellung und ihre verwendung

Also Published As

Publication number Publication date
EP0336441A2 (en) 1989-10-11
JP2639684B2 (ja) 1997-08-13
ES2056995T3 (es) 1994-10-16
EP0336441B1 (en) 1994-06-15
EP0336441A3 (en) 1990-05-16
DE68916088D1 (de) 1994-07-21
CA1335355C (en) 1995-04-25
JPH01257495A (ja) 1989-10-13
DE68916088T2 (de) 1995-01-26

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