KR890014468A - 텔루륨 및 세렌 유도체의 착화합물 - Google Patents

텔루륨 및 세렌 유도체의 착화합물 Download PDF

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Publication number
KR890014468A
KR890014468A KR1019890003041A KR890003041A KR890014468A KR 890014468 A KR890014468 A KR 890014468A KR 1019890003041 A KR1019890003041 A KR 1019890003041A KR 890003041 A KR890003041 A KR 890003041A KR 890014468 A KR890014468 A KR 890014468A
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South Korea
Prior art keywords
carbon atoms
complex
compound
complexing
complexing agent
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KR1019890003041A
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KR0156543B1 (ko
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스레드니 벤자민
알벡 미카엘
파브리브 레오
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원본미기재
바-일란 유니버시티
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Priority claimed from US07/172,643 external-priority patent/US4929739A/en
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Publication of KR890014468A publication Critical patent/KR890014468A/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C391/00—Compounds containing selenium
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D329/00—Heterocyclic compounds containing rings having oxygen and selenium or oxygen and tellurium atoms as the only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/065—Diphenyl-substituted acyclic alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C395/00—Compounds containing tellurium

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

내용 없음.

Description

텔루륨 및 셀렌 유도체의 착화합물
내용없음

Claims (16)

  1. 하기 일반식(A) 내지 (E)중의 하나의 화합물과 약제학적으로 허용되는 무독성 착화제와의 착화합물.
    상기식에서, Q는 Te 또는 Se이고 ; t는 1 또는 0이며 ; u는 1 또는 0이고 ; v는 1 또는 0이며 ; R, R1, R2, R3, R4, R5, R6, R7, R8및 R9은 동일하거나 상이하고, 독립적으로 수소, 탄수소 1 내지 5의 하이드록시알킬, 하이드록시, 탄소수 1 내지 5의 알킬, 할로겐 탄소수 1 내지 5의 할로알킬, 카복시, 탄소수 2 내지 10의 알킬카보닐알킬, 탄소수 1 내지 5의 알카노일옥시, 탄소수 1 내지 5의 카복시알킬, 아실, 아미도, 시아노, 탄소수 1 내지 5의 아미도알킬, 탄소수 2 내지 10의 N-모노알킬아미도알킬, 탄소수 4 내지 10의 N,N-디알킬아미도알킬, 탄소수 1 내지 5의 시아노알킬, 탄소수 1 내지 5의 알콕시, 탄소수 2 내지 10의 알콕시알킬, 및 -COR10(여기에서, R10은 탄소수 1 내지 5의 알킬이다)중에서 선택되며 ; X는 할로겐이다.
  2. 제1항에 있어서, 착화제가 하이드록시 폴리 카복실산, 폴리카복실산 및 폴리하이드록시 폴리카복실산중에서 선택되는 착화합물.
  3. 제2항에 있어서, 착화제가 하이드록시 폴리카복실산인 착화합물.
  4. 제2항에 있어서, 착화제가 폴리카복실산인 착화합물.
  5. 제2항에 있어서, 착화제가 폴리하이드록시 폴리카복실산인 착화합물.
  6. 제2항에 있어서, 화합물이 하기 구조식의 화합물인 착화합물.
  7. 제6항에 있어서, 시트레이트 이온을 함유하는 착화합물.
  8. 제6항에 있어서, 타르트레이트 이온을 함유하는 착화합물.
  9. 제1항의 착화합물 및 약제학적 담체를 함유함을 특징으로 하는 약제학적 조성물.
  10. 제7항의 착화합물 및 약제학적 담체를 함유함을 특징으로 하는 약제학적 조성물.
  11. 제8항의 착화합물 및 약제학적 담체를 함유함을 특징으로 하는 약제학적 조성물.
  12. 제4항의 착화합물 및 약제학적 담체를 함유함을 특징으로 하는 약제학적 조성물.
  13. 세포를 자극시켜 림포킨(lymphokine)을 생성시키는 방법에 있어서, 림포킨-생성 세포를 제1항의 착화합물과 접촉시킴을 특징으로 하는 방법.
  14. 세포를 자극시켜 림포킨을 생성시키는 방법에 있어서, 림포킨-생성 세포를 제7항의 착화합물과 접촉시킴을 특징으로 하는 방법.
  15. 세포를 자극시켜 림포킨을 생성시키는 방법에 있어서, 림포킨-생성 세포를 제8항의 착화합물과 접촉시킴을 특징으로 하는 방법.
  16. 세포를 자극시켜 림포킨을 생성시키는 방법에 있어서, 림포킨-생성 세포를 제9항의 착화합물과 접촉시킴을 특징으로 하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019890003041A 1988-03-14 1989-03-13 텔루륨 및 셀레늄 유도체의 착화합물 및 이를 포함하는 약제학적 조성물 KR0156543B1 (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US16758488A 1988-03-14 1988-03-14
IL167584 1988-03-14
US167,584 1988-03-14
US07/172,643 US4929739A (en) 1988-03-24 1988-03-24 Complexes of tellurium and selenium derivatives
IL172643 1988-03-24
US172,643 1988-03-24

Publications (2)

Publication Number Publication Date
KR890014468A true KR890014468A (ko) 1989-10-23
KR0156543B1 KR0156543B1 (ko) 1998-12-01

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KR1019890003041A KR0156543B1 (ko) 1988-03-14 1989-03-13 텔루륨 및 셀레늄 유도체의 착화합물 및 이를 포함하는 약제학적 조성물

Country Status (18)

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EP (1) EP0333263B1 (ko)
JP (1) JP2659428B2 (ko)
KR (1) KR0156543B1 (ko)
AR (1) AR247562A1 (ko)
AT (1) ATE99684T1 (ko)
AU (1) AU608955B2 (ko)
BR (1) BR8901161A (ko)
CA (1) CA1327047C (ko)
DE (1) DE68911959T2 (ko)
DK (1) DK167148B1 (ko)
ES (1) ES2061932T3 (ko)
FI (1) FI91753C (ko)
HU (1) HU206122B (ko)
IE (1) IE63675B1 (ko)
IL (1) IL89462A (ko)
NZ (1) NZ228144A (ko)
PH (1) PH25740A (ko)
PT (1) PT89988B (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPM402094A0 (en) * 1994-02-18 1994-03-17 University Of Sydney, The Chemical compounds
AT412448B (de) * 2001-02-13 2005-03-25 Vis Vitalis Lizenz & Handels Verwendung von selenhältigen präparaten
IL146694A (en) 2001-11-22 2010-12-30 Biomas Ltd Use of an aqueous solution containing a biologically active complex of tellurium dioxide for manufacturing a medicament

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4525443A (en) * 1983-10-17 1985-06-25 Eastman Kodak Company Novel 3-trihalochalcogenpropenone compounds
US4761490A (en) * 1985-03-15 1988-08-02 Bar-Ilan University Organic derivatives of tellurium and selenium and their use to stimulate cytokine production

Also Published As

Publication number Publication date
AU3127989A (en) 1989-09-14
DE68911959T2 (de) 1994-07-14
BR8901161A (pt) 1989-10-31
EP0333263B1 (en) 1994-01-05
IL89462A (en) 1994-07-31
DK120689A (da) 1989-09-15
FI891205A (fi) 1989-09-15
EP0333263A1 (en) 1989-09-20
DE68911959D1 (de) 1994-02-17
DK120689D0 (da) 1989-03-13
ATE99684T1 (de) 1994-01-15
PT89988B (pt) 1994-05-31
FI891205A0 (fi) 1989-03-14
AR247562A1 (es) 1995-01-31
JP2659428B2 (ja) 1997-09-30
KR0156543B1 (ko) 1998-12-01
JPH0242056A (ja) 1990-02-13
IE63675B1 (en) 1995-05-31
IE890801L (en) 1989-09-14
PT89988A (pt) 1989-11-10
DK167148B1 (da) 1993-09-06
NZ228144A (en) 1991-03-26
ES2061932T3 (es) 1994-12-16
AU608955B2 (en) 1991-04-18
CA1327047C (en) 1994-02-15
IL89462A0 (en) 1989-09-10
PH25740A (en) 1991-10-18
HU206122B (en) 1992-08-28
FI91753C (fi) 1994-08-10
FI91753B (fi) 1994-04-29

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