KR890005110A - 신규의 3-아로일-6,7-디히드로-5h-피롤로[1,2-c]이미다졸-7-카르복시산유도체 - Google Patents
신규의 3-아로일-6,7-디히드로-5h-피롤로[1,2-c]이미다졸-7-카르복시산유도체 Download PDFInfo
- Publication number
- KR890005110A KR890005110A KR1019880011667A KR880011667A KR890005110A KR 890005110 A KR890005110 A KR 890005110A KR 1019880011667 A KR1019880011667 A KR 1019880011667A KR 880011667 A KR880011667 A KR 880011667A KR 890005110 A KR890005110 A KR 890005110A
- Authority
- KR
- South Korea
- Prior art keywords
- group
- aroyl
- pyrrolo
- dihydro
- imidazole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (1)
- 다음의 일반식(I)로 표시되는 3-아로일-6,7-디히드로-5H-피롤로(1,2-C)이미다졸-7-카르복시산 유도체에서R1은 수소원자, 할로겐원자, 트리할로메틸기, 알킬기, 알콕시기, 알킬티오기, 알킬술피닐기 또는 알킬술포닐기이며 Ar은 비치환 또는 치환된 페닐기이거나 비치환 또는 치환된 헤테로 고리기이며 R2는 히드록실기, 에스테르잔류물, 또는 아미노기인것을 특징으로하는 신규의 3-아로일-6,7-디히드로-5H-피를로[1,2-C]이미다졸-7-카르복시산유도체.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP227702 | 1987-09-10 | ||
| JP62227702A JPH0739418B2 (ja) | 1987-09-10 | 1987-09-10 | 新規な３−アロイル−６，７−ジヒドロ−５Ｈ−ピロロ〔１，２−ｃ〕イミダゾール−７−カルボン酸誘導体 |
| JP62-227702 | 1987-09-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR890005110A true KR890005110A (ko) | 1989-05-11 |
| KR900006450B1 KR900006450B1 (ko) | 1990-08-31 |
Family
ID=16865008
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019880011667A KR900006450B1 (ko) | 1987-09-10 | 1988-09-09 | 신규의 3-아로일-6,7-디히드로-5h-피롤로[1,2-c]이미다졸-7-카르복시산유도체 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4895956A (ko) |
| EP (1) | EP0307034A1 (ko) |
| JP (1) | JPH0739418B2 (ko) |
| KR (1) | KR900006450B1 (ko) |
| CN (1) | CN1032012A (ko) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101676288A (zh) * | 2008-09-04 | 2010-03-24 | 上海交通大学 | 一类具有双环结构的咪唑类手性有机小分子化合物及其合成方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS539788A (en) * | 1976-07-14 | 1978-01-28 | Syntex Inc | 55aloyll1*22dihydroo3hh pyroro *1*22a* pyroll11 carboxylic acid derivative |
| US4337346A (en) * | 1978-11-02 | 1982-06-29 | Sumitomo Chemical Company, Limited | α-Hydroxyaldehyde and a process for preparing the same |
| US4347185A (en) * | 1980-10-20 | 1982-08-31 | Syntex (U.S.A.) Inc. | Processes for preparing 5-benzoyl-7-halo-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acids |
| US4612325A (en) * | 1982-06-08 | 1986-09-16 | Syntex (U.S.A) Inc. | 5-Aroyl-6-alkylthio-1,2-dihydro-3H-pyrrolo(1,2-A)pyrrole-1-carboxylic acids and use thereof as analgesics and anti-inflammatories |
| US4511724A (en) * | 1982-06-10 | 1985-04-16 | Merck & Co., Inc. | 5-(Pyrrol-2-oyl)-1,2-dihydro-3H-pyrrolo [1,2-a]pyrrole derivatives as anti-inflammatory and analgesic agents |
-
1987
- 1987-09-10 JP JP62227702A patent/JPH0739418B2/ja not_active Expired - Fee Related
-
1988
- 1988-08-31 EP EP88201857A patent/EP0307034A1/en not_active Withdrawn
- 1988-09-01 CN CN88106453A patent/CN1032012A/zh active Pending
- 1988-09-08 US US07/242,331 patent/US4895956A/en not_active Expired - Fee Related
- 1988-09-09 KR KR1019880011667A patent/KR900006450B1/ko not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR900006450B1 (ko) | 1990-08-31 |
| US4895956A (en) | 1990-01-23 |
| JPS6470488A (en) | 1989-03-15 |
| EP0307034A1 (en) | 1989-03-15 |
| CN1032012A (zh) | 1989-03-29 |
| JPH0739418B2 (ja) | 1995-05-01 |
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| G160 | Decision to publish patent application | ||
| E701 | Decision to grant or registration of patent right | ||
| GRNT | Written decision to grant | ||
| FPAY | Annual fee payment |
Payment date: 19930830 Year of fee payment: 4 |
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| LAPS | Lapse due to unpaid annual fee |