KR840004096A - 페녹시 프로판올아민 유도체 - Google Patents

페녹시 프로판올아민 유도체 Download PDF

Info

Publication number
KR840004096A
KR840004096A KR1019830001105A KR830001105A KR840004096A KR 840004096 A KR840004096 A KR 840004096A KR 1019830001105 A KR1019830001105 A KR 1019830001105A KR 830001105 A KR830001105 A KR 830001105A KR 840004096 A KR840004096 A KR 840004096A
Authority
KR
South Korea
Prior art keywords
group
phenoxy
lower alkyl
halogen
propanolamine derivatives
Prior art date
Application number
KR1019830001105A
Other languages
English (en)
Inventor
요시아끼(외 4) 아오야기
Original Assignee
모리시따 히로시
닛본 신야꾸 가부시기가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 모리시따 히로시, 닛본 신야꾸 가부시기가이샤 filed Critical 모리시따 히로시
Publication of KR840004096A publication Critical patent/KR840004096A/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

내용 없음

Description

페녹시 프로판올아민 유도체
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (1)

  1. 다음의 일반식(Ⅰ)
    (식중 R1은 수소, 할로겐, 또는 저급알킬기를 표시한다.
    R2는 α위에 카르보닐기를 가지거나 또는 가지지 않는 피로리디노, 피페리디노, 모르폴리노 또는 퍼히드로아제 피노기를 표시한다. R3은 수소, 저급알킬기, 또는 알콕시카르보닐기를 표시한다. R4는 수소, α저급알콕시기로 치환되거나 또는 무치환의 저급알킬기, 저급알콕시기, 할로겐, 또는 저급알카노일기를 표시한다)로 표시되는 1-페녹시-3-(4-페닐피페라디노)-2-프로판올유도체 및 그 약리적으로 허용할 수 있는 염.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019830001105A 1982-03-18 1983-03-18 페녹시 프로판올아민 유도체 KR840004096A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP44089 1982-03-18
JP57044089A JPS58164583A (ja) 1982-03-18 1982-03-18 フエノキシプロパノ−ルアミン誘導体

Publications (1)

Publication Number Publication Date
KR840004096A true KR840004096A (ko) 1984-10-06

Family

ID=12681891

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019830001105A KR840004096A (ko) 1982-03-18 1983-03-18 페녹시 프로판올아민 유도체

Country Status (7)

Country Link
US (1) US4642307A (ko)
EP (1) EP0089634B1 (ko)
JP (1) JPS58164583A (ko)
KR (1) KR840004096A (ko)
CA (1) CA1195328A (ko)
DE (1) DE3364323D1 (ko)
ES (1) ES8405779A1 (ko)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58164583A (ja) * 1982-03-18 1983-09-29 Nippon Shinyaku Co Ltd フエノキシプロパノ−ルアミン誘導体
DE3424685A1 (de) * 1984-07-05 1986-02-06 Beiersdorf Ag, 2000 Hamburg Neue substituierte phenylpiperazinyl-propanole, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
US5213770A (en) * 1987-12-03 1993-05-25 United Technologies Corporation Methane conversion reactor
DE3918542A1 (de) * 1989-06-07 1990-12-13 Boehringer Mannheim Gmbh Hydroxylierte 1-phenyl-4-(3-(napthth-1-yl-oxy)-2-hydroxy -propyl)-piperazine, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
US5393735A (en) * 1990-08-09 1995-02-28 Rohm And Haas Company Herbicidal glutarimides
TW275614B (ko) * 1993-02-15 1996-05-11 Senju Pharma Co
CA2172183A1 (en) * 1995-03-29 1996-09-30 Kazumi Ogata Piperazine derivative
AU1057401A (en) * 1999-11-11 2001-06-06 Senju Pharmaceutical Co., Ltd. Pancreatitis remedies
PE20020195A1 (es) * 2000-07-13 2002-03-12 Lilly Co Eli AGONISTAS ß3 ADRENERGICOS
US7943605B2 (en) * 2005-10-27 2011-05-17 Ucb Pharma S.A. Compounds comprising a lactam or a lactam derivative moiety, processes for making them, and their uses

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA967965A (en) * 1968-12-24 1975-05-20 Hoffmann-La Roche Limited Aromatic ethers and process for the manufacture thereof
GB1317479A (en) * 1970-11-10 1973-05-16 Pfizer Ltd 1-2-hydroxy-3-phenoxy or phenylthiopropyl-4-phenyl-piperazine derivatives
DE2354444A1 (de) * 1973-10-31 1975-05-07 Merck Patent Gmbh Biphenylylaether und verfahren zu ihrer herstellung
JPS56115769A (en) * 1980-02-18 1981-09-11 Tanabe Seiyaku Co Ltd Piperazine derivative and its preparation
DE3101456A1 (de) * 1981-01-19 1982-09-02 Basf Ag, 6700 Ludwigshafen Phenylpiperazinyl-propanole von hetarylphenolen, ihre herstellung und diese enthaltende therapeutische mittel
JPS58164583A (ja) * 1982-03-18 1983-09-29 Nippon Shinyaku Co Ltd フエノキシプロパノ−ルアミン誘導体

Also Published As

Publication number Publication date
EP0089634A1 (en) 1983-09-28
ES520712A0 (es) 1984-06-16
JPS58164583A (ja) 1983-09-29
DE3364323D1 (de) 1986-08-07
US4642307A (en) 1987-02-10
EP0089634B1 (en) 1986-07-02
CA1195328A (en) 1985-10-15
ES8405779A1 (es) 1984-06-16

Similar Documents

Publication Publication Date Title
KR890005084A (ko) 퀴놀린 유도체
KR840004441A (ko) 포스포리피드 유도체의 제조방법
KR840004096A (ko) 페녹시 프로판올아민 유도체
KR910006423A (ko) 아닐린에 근거하는 유응성 아조염료
KR860001097A (ko) 4-아미노-2-페닐퀴놀린의 제조방법
KR840008342A (ko) 모르포린 유도체의 제조방법
KR830005325A (ko) 수용성 화학 발광 시스템
KR830005168A (ko) 5-(디하이드록시페녹시)테트라졸의 제조방법
KR850008159A (ko) 2-페닐-4,5,6,7-테트라히드로-2h-인다졸류의 제조방법
KR880005076A (ko) 2-아제티디논 유도체
KR920001242A (ko) 포지티브 레지스트 조성물
KR890004994A (ko) 신규 백금 착화합물
KR840001144A (ko) 5(6)-페닐설포닐옥시-벤즈이미다졸 유도체의 제조방법
KR930700433A (ko) 신규 디술피드 화합물
KR840005108A (ko) 농업용 살균 조성물
KR880001578A (ko) 안식향산 유도체
KR860004008A (ko) 부타놀유도체의 제법
KR890005560A (ko) 액정표시용 2색성색소
KR830005158A (ko) 벤조이미다조릴 프로피온산 유도체의 제조방법
KR870007115A (ko) 피로글루타미드 유도체
KR890001956A (ko) 안식향산 유도체
KR850007064A (ko) 0.0-디메틸디티오포스포릴페닐 아세트산의 안정화 방법
KR830001846A (ko) 비페닐 유도체의 제법
KR910009192A (ko) 잎담배 건조용 합성수지 필름
KR830004371A (ko) 새로운 불수용성 아조염료

Legal Events

Date Code Title Description
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid