KR840004096A - 페녹시 프로판올아민 유도체 - Google Patents
페녹시 프로판올아민 유도체 Download PDFInfo
- Publication number
- KR840004096A KR840004096A KR1019830001105A KR830001105A KR840004096A KR 840004096 A KR840004096 A KR 840004096A KR 1019830001105 A KR1019830001105 A KR 1019830001105A KR 830001105 A KR830001105 A KR 830001105A KR 840004096 A KR840004096 A KR 840004096A
- Authority
- KR
- South Korea
- Prior art keywords
- group
- phenoxy
- lower alkyl
- halogen
- propanolamine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (1)
- 다음의 일반식(Ⅰ)(식중 R1은 수소, 할로겐, 또는 저급알킬기를 표시한다.R2는 α위에 카르보닐기를 가지거나 또는 가지지 않는 피로리디노, 피페리디노, 모르폴리노 또는 퍼히드로아제 피노기를 표시한다. R3은 수소, 저급알킬기, 또는 알콕시카르보닐기를 표시한다. R4는 수소, α저급알콕시기로 치환되거나 또는 무치환의 저급알킬기, 저급알콕시기, 할로겐, 또는 저급알카노일기를 표시한다)로 표시되는 1-페녹시-3-(4-페닐피페라디노)-2-프로판올유도체 및 그 약리적으로 허용할 수 있는 염.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP44089 | 1982-03-18 | ||
JP57044089A JPS58164583A (ja) | 1982-03-18 | 1982-03-18 | フエノキシプロパノ−ルアミン誘導体 |
Publications (1)
Publication Number | Publication Date |
---|---|
KR840004096A true KR840004096A (ko) | 1984-10-06 |
Family
ID=12681891
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019830001105A KR840004096A (ko) | 1982-03-18 | 1983-03-18 | 페녹시 프로판올아민 유도체 |
Country Status (7)
Country | Link |
---|---|
US (1) | US4642307A (ko) |
EP (1) | EP0089634B1 (ko) |
JP (1) | JPS58164583A (ko) |
KR (1) | KR840004096A (ko) |
CA (1) | CA1195328A (ko) |
DE (1) | DE3364323D1 (ko) |
ES (1) | ES8405779A1 (ko) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58164583A (ja) * | 1982-03-18 | 1983-09-29 | Nippon Shinyaku Co Ltd | フエノキシプロパノ−ルアミン誘導体 |
DE3424685A1 (de) * | 1984-07-05 | 1986-02-06 | Beiersdorf Ag, 2000 Hamburg | Neue substituierte phenylpiperazinyl-propanole, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen |
US5213770A (en) * | 1987-12-03 | 1993-05-25 | United Technologies Corporation | Methane conversion reactor |
DE3918542A1 (de) * | 1989-06-07 | 1990-12-13 | Boehringer Mannheim Gmbh | Hydroxylierte 1-phenyl-4-(3-(napthth-1-yl-oxy)-2-hydroxy -propyl)-piperazine, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten |
US5393735A (en) * | 1990-08-09 | 1995-02-28 | Rohm And Haas Company | Herbicidal glutarimides |
TW275614B (ko) * | 1993-02-15 | 1996-05-11 | Senju Pharma Co | |
CA2172183A1 (en) * | 1995-03-29 | 1996-09-30 | Kazumi Ogata | Piperazine derivative |
AU1057401A (en) * | 1999-11-11 | 2001-06-06 | Senju Pharmaceutical Co., Ltd. | Pancreatitis remedies |
PE20020195A1 (es) * | 2000-07-13 | 2002-03-12 | Lilly Co Eli | AGONISTAS ß3 ADRENERGICOS |
US7943605B2 (en) * | 2005-10-27 | 2011-05-17 | Ucb Pharma S.A. | Compounds comprising a lactam or a lactam derivative moiety, processes for making them, and their uses |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA967965A (en) * | 1968-12-24 | 1975-05-20 | Hoffmann-La Roche Limited | Aromatic ethers and process for the manufacture thereof |
GB1317479A (en) * | 1970-11-10 | 1973-05-16 | Pfizer Ltd | 1-2-hydroxy-3-phenoxy or phenylthiopropyl-4-phenyl-piperazine derivatives |
DE2354444A1 (de) * | 1973-10-31 | 1975-05-07 | Merck Patent Gmbh | Biphenylylaether und verfahren zu ihrer herstellung |
JPS56115769A (en) * | 1980-02-18 | 1981-09-11 | Tanabe Seiyaku Co Ltd | Piperazine derivative and its preparation |
DE3101456A1 (de) * | 1981-01-19 | 1982-09-02 | Basf Ag, 6700 Ludwigshafen | Phenylpiperazinyl-propanole von hetarylphenolen, ihre herstellung und diese enthaltende therapeutische mittel |
JPS58164583A (ja) * | 1982-03-18 | 1983-09-29 | Nippon Shinyaku Co Ltd | フエノキシプロパノ−ルアミン誘導体 |
-
1982
- 1982-03-18 JP JP57044089A patent/JPS58164583A/ja active Pending
-
1983
- 1983-03-17 CA CA000423792A patent/CA1195328A/en not_active Expired
- 1983-03-17 ES ES520712A patent/ES8405779A1/es not_active Expired
- 1983-03-17 EP EP83102667A patent/EP0089634B1/en not_active Expired
- 1983-03-17 DE DE8383102667T patent/DE3364323D1/de not_active Expired
- 1983-03-18 US US06/476,857 patent/US4642307A/en not_active Expired - Fee Related
- 1983-03-18 KR KR1019830001105A patent/KR840004096A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP0089634A1 (en) | 1983-09-28 |
ES520712A0 (es) | 1984-06-16 |
JPS58164583A (ja) | 1983-09-29 |
DE3364323D1 (de) | 1986-08-07 |
US4642307A (en) | 1987-02-10 |
EP0089634B1 (en) | 1986-07-02 |
CA1195328A (en) | 1985-10-15 |
ES8405779A1 (es) | 1984-06-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |