KR880701777A - 재조합 dna 방법에 의해 제조된 인간의 췌장 분비 트립신 억제제와 그의 제조방법 - Google Patents

재조합 dna 방법에 의해 제조된 인간의 췌장 분비 트립신 억제제와 그의 제조방법

Info

Publication number
KR880701777A
KR880701777A KR1019880700752A KR880700752A KR880701777A KR 880701777 A KR880701777 A KR 880701777A KR 1019880700752 A KR1019880700752 A KR 1019880700752A KR 880700752 A KR880700752 A KR 880700752A KR 880701777 A KR880701777 A KR 880701777A
Authority
KR
South Korea
Prior art keywords
recombinant dna
trypsin inhibitor
human pancreatic
manufacturing same
pancreatic secretion
Prior art date
Application number
KR1019880700752A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of KR880701777A publication Critical patent/KR880701777A/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8135—Kazal type inhibitors, e.g. pancreatic secretory inhibitor, ovomucoid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1019880700752A 1986-10-30 1988-06-29 재조합 dna 방법에 의해 제조된 인간의 췌장 분비 트립신 억제제와 그의 제조방법 KR880701777A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92499186A 1986-10-30 1986-10-30
PCT/US1987/002585 WO1988003171A1 (en) 1986-10-30 1987-10-09 Human pancreatic secretory trypsin inhibitors produced by recombinant dna methods and processes for the production of same

Publications (1)

Publication Number Publication Date
KR880701777A true KR880701777A (ko) 1988-11-05

Family

ID=25451045

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880700752A KR880701777A (ko) 1986-10-30 1988-06-29 재조합 dna 방법에 의해 제조된 인간의 췌장 분비 트립신 억제제와 그의 제조방법

Country Status (5)

Country Link
EP (1) EP0329693A4 (ko)
JP (1) JPH02501027A (ko)
KR (1) KR880701777A (ko)
AU (1) AU8172787A (ko)
WO (1) WO1988003171A1 (ko)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0616716B2 (ja) * 1986-10-14 1994-03-09 塩野義製薬株式会社 酵母におけるヒトｐｓｔｉの製造法
DE3786870T2 (de) * 1986-10-14 1993-11-11 Shionogi Seiyaku Kk Methode zur Herstellung von Proteinen.
GB2199582A (en) * 1987-01-07 1988-07-13 Bayer Ag Analogues of pancreatic secretory trypsin inhibitor
JPS6427473A (en) * 1987-07-23 1989-01-30 Mochida Pharm Co Ltd Human pancreas-secreting trypsin inhibitor and production thereof
JPH07102137B2 (ja) * 1988-07-19 1995-11-08 塩野義製薬株式会社 修飾ヒトｐｓｔｉ
US5223407A (en) * 1988-08-31 1993-06-29 Allelix Inc. Excretion of heterologous proteins from e. coli
US5646015A (en) * 1988-08-31 1997-07-08 Astra Ab Excretion of heterologous proteins from E. coli
DE3907492A1 (de) * 1989-03-08 1990-09-13 Biotechnolog Forschung Gmbh Verfahren zur isolierung und reinigung von hpsti und hpsti-varianten
JPH09124698A (ja) * 1995-10-27 1997-05-13 Sagami Chem Res Center ヒトｐｅｃ−６０様蛋白質およびそれをコードするｄｎａ
SE9702401D0 (sv) 1997-06-19 1997-06-19 Astra Ab Pharmaceutical use
AT410444B (de) * 2001-03-02 2003-04-25 Oesterr Forsch Seibersdorf Verfahren zur detektion von nukleinsäuremolekülen
KR101629702B1 (ko) 2007-02-12 2016-06-13 체에스엘 베링 게엠베하 카잘-형 세린 프로테아제 억제제의 치료학적 적용

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU204563B (en) * 1984-12-06 1992-01-28 Synergen Biolog Inc Process for producing recombinant serine-protease inhibitors and dns sequencyes for them
JPH0616716B2 (ja) * 1986-10-14 1994-03-09 塩野義製薬株式会社 酵母におけるヒトｐｓｔｉの製造法
DE3786870T2 (de) * 1986-10-14 1993-11-11 Shionogi Seiyaku Kk Methode zur Herstellung von Proteinen.
GB2199582A (en) * 1987-01-07 1988-07-13 Bayer Ag Analogues of pancreatic secretory trypsin inhibitor

Also Published As

Publication number Publication date
EP0329693A1 (en) 1989-08-30
AU8172787A (en) 1988-05-25
JPH02501027A (ja) 1990-04-12
WO1988003171A1 (en) 1988-05-05
EP0329693A4 (en) 1989-09-26

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Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
E601 Decision to refuse application