KR880006186A - 4-하이드록시-4-(치환된 알케닐)사이클로헥산 카복실산 - Google Patents
4-하이드록시-4-(치환된 알케닐)사이클로헥산 카복실산 Download PDFInfo
- Publication number
- KR880006186A KR880006186A KR870012473A KR870012473A KR880006186A KR 880006186 A KR880006186 A KR 880006186A KR 870012473 A KR870012473 A KR 870012473A KR 870012473 A KR870012473 A KR 870012473A KR 880006186 A KR880006186 A KR 880006186A
- Authority
- KR
- South Korea
- Prior art keywords
- lower alkyl
- alkyl
- hydroxy
- compound
- hydrogen
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/22—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and doubly-bound oxygen atoms bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/55—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing rings other than six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Immunology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Epoxy Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (8)
- 하기일반식(I)의 화합물.상기식에서, n은 0내지 2의 정수이고 R은 탄소원자수 6내지 15의 직쇄 알킬이고 x는 수소이거나, n이 1 또는 2인 경우, x는 -NH2일수 있고, Y는 하이드록시, -0-(저급알킬), -NH2-NH(저급알킬), -N-(저급알킬)2또는(여기에서는 R'는 수소, 탄소원자수 1내지 4의 알킬 또는 벤질이다)이며, Z는 하이드록시, -O-(저급알킬), -HN2-NH-(저급알킬)또는 N-(저급알킬)2이다.
- 제1항에 있어서, 하기 일반식의 화합물.`상기식에서, n은 0내지 2의 정수이고 R은 탄소원자수 6내지 15의 직쇄 알킬이고 X는 수소이거나, n이 1 또는 2인 경우, X는 -NH2일수 있고, Y는 하이드록시, -0-(저급알킬), -NH2-NH(저급알킬), -N-(저급알킬)2또는(여기에서는 R'는 수소, 탄소원자수 1내지 4의 알킬 또는 벤질이다)이며; Z는 하이드록시, -O-(저급알킬), -HN2-NH-(저급알킬)또는 N-(저급알킬)2이다.
- 제1항에 있어서, 하기 일반식의 화합물.`상기식에서, n은 0내지 2의 정수이고; R은 탄소원자수 6내지 15의 직쇄 알킬이고; Y"는 하이드록시, -NH2-NH(저급알킬), -N-(저급알킬)2또는(여기에서는 R'는 수소, 탄소원자수 1내지 4의 알킬 또는 벤질이다)이다.
- 제1항에 있어서, [4(R)-[1X4β, 4(Z)]]-4-[1-[(카복시메틸)티오]-2-헥사데세닐]-4-하이드록시사이클로 헥산카복실산인 화합물.
- 제1항에 있어서, [1αX4β, 4(Z)]-4-[1-[(2-카복시메틸)티오]-2-헥사데세닐]-4-하이드록시사이클로 헥산카복실산인 화합물.
- 제1항에 있어서, [4(R)-[1α,4β, 4(Z)]-4-[1-[(2-카복시에틸)티오]-2-헥사데세닐-4-하이드록시사이클로헥산카복실산인 화합물.
- 제1항에 있어서, [1α,4β, 4(Z)]-4-[1-[(3-카복시프로필)티오]-2-헥사데세닐]-4-하이드록시사이클로헥산카복실산인 화합물.
- 일반식(I)의 에폭사이드를 적절한 용매중 염기 존재하에 일반식(Ⅱ)의 멀캅토알카노산 유도체와 반응시키고, 임의로 Y', Y" 또는 Z'가 -O-(저급알킬)인 경우 강한 무기 염기로 처리하고 강산으로 산성화시켜 Y', Y"또는 Z가-OH인 화합물을 제조함을 특징으로 하여 일반식(I)의 화합물을 제조하는 방법.상기식에서, n은 0내지 2의 정수이고; R은 탄소원자수 6내지 15의 직쇄 알킬이고; X는 수소이거나, n은 1 또는 2인 경우, X는 -NH2일수 있고, Y는 하이드록시, -0-(저급알킬), -NH2-NH(저급알킬), 또는 -N-(저급알킬)2또는(여기어서 R'는 수소, 탄소원자 1내지 4의 알킬 또는 벤질이다)이며; Z는 하이드록시, -O-(저급알킬), -HN2-NH-(저급알킬), 또는 N-(저급알킬)2이고, X는 수소이거나, n이 1또는 2인 경우, -Q-NH-(여기서, Q는 아민 보호 그룹이다) 일 수 있으며, Y"는 -O-(저급알킬), -NH2, -NH(저급알킬),-N-(저급알킬)2또는(여기서, Y"는 -O-(저급알킬)이다.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/928,759 US4748274A (en) | 1986-11-07 | 1986-11-07 | 4-hydroxy-4-(substituted alkenyl)cyclohexanecarboxylic acids |
US928759 | 1986-11-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR880006186A true KR880006186A (ko) | 1988-07-22 |
KR950005775B1 KR950005775B1 (ko) | 1995-05-30 |
Family
ID=25456699
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019870012473A KR950005775B1 (ko) | 1986-11-07 | 1987-11-06 | 4-하이드록시-4-(치환된 알케닐)사이클로헥산 카복실산 |
Country Status (21)
Country | Link |
---|---|
US (1) | US4748274A (ko) |
EP (1) | EP0270843B1 (ko) |
JP (1) | JPH07113011B2 (ko) |
KR (1) | KR950005775B1 (ko) |
CN (1) | CN1009088B (ko) |
AT (1) | ATE61352T1 (ko) |
AU (1) | AU595397B2 (ko) |
CA (1) | CA1296740C (ko) |
DE (1) | DE3768449D1 (ko) |
DK (1) | DK583887A (ko) |
ES (1) | ES2036561T3 (ko) |
FI (1) | FI87923C (ko) |
GR (1) | GR3002075T3 (ko) |
HU (1) | HU197880B (ko) |
IE (1) | IE872998L (ko) |
IL (1) | IL84364A (ko) |
NO (1) | NO167382C (ko) |
NZ (1) | NZ222427A (ko) |
PH (1) | PH24148A (ko) |
PT (1) | PT86093B (ko) |
ZA (1) | ZA878217B (ko) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102082304B1 (ko) | 2013-05-02 | 2020-02-27 | 에스케이케미칼 주식회사 | 공중합 폴리에스테르 수지 및 이를 이용한 성형제품 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4622422A (en) * | 1985-08-23 | 1986-11-11 | Merrell Dow Pharmaceuticals Inc. | Cyclohexanealkanoic acids |
-
1986
- 1986-11-07 US US06/928,759 patent/US4748274A/en not_active Expired - Lifetime
-
1987
- 1987-11-02 ZA ZA878217A patent/ZA878217B/xx unknown
- 1987-11-02 FI FI874821A patent/FI87923C/fi not_active IP Right Cessation
- 1987-11-02 AU AU80604/87A patent/AU595397B2/en not_active Expired
- 1987-11-02 CA CA000550754A patent/CA1296740C/en not_active Expired - Lifetime
- 1987-11-03 NZ NZ222427A patent/NZ222427A/xx unknown
- 1987-11-04 IL IL84364A patent/IL84364A/xx unknown
- 1987-11-05 AT AT87116316T patent/ATE61352T1/de not_active IP Right Cessation
- 1987-11-05 JP JP62278441A patent/JPH07113011B2/ja not_active Expired - Fee Related
- 1987-11-05 ES ES198787116316T patent/ES2036561T3/es not_active Expired - Lifetime
- 1987-11-05 EP EP87116316A patent/EP0270843B1/en not_active Expired - Lifetime
- 1987-11-05 DE DE8787116316T patent/DE3768449D1/de not_active Expired - Lifetime
- 1987-11-06 PT PT86093A patent/PT86093B/pt not_active IP Right Cessation
- 1987-11-06 HU HU874977A patent/HU197880B/hu not_active IP Right Cessation
- 1987-11-06 CN CN87107599A patent/CN1009088B/zh not_active Expired
- 1987-11-06 IE IE872998A patent/IE872998L/xx unknown
- 1987-11-06 DK DK583887A patent/DK583887A/da not_active Application Discontinuation
- 1987-11-06 KR KR1019870012473A patent/KR950005775B1/ko not_active IP Right Cessation
- 1987-11-06 NO NO874627A patent/NO167382C/no unknown
- 1987-11-06 PH PH36045A patent/PH24148A/en unknown
-
1991
- 1991-06-06 GR GR91400745T patent/GR3002075T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
NO874627L (no) | 1988-05-09 |
FI874821A0 (fi) | 1987-11-02 |
AU8060487A (en) | 1988-07-28 |
US4748274A (en) | 1988-05-31 |
ATE61352T1 (de) | 1991-03-15 |
NO167382C (no) | 1991-10-30 |
DK583887A (da) | 1988-05-08 |
EP0270843A1 (en) | 1988-06-15 |
GR3002075T3 (en) | 1992-12-30 |
FI874821A (fi) | 1988-05-08 |
AU595397B2 (en) | 1990-03-29 |
IL84364A0 (en) | 1988-04-29 |
FI87923C (fi) | 1993-03-10 |
KR950005775B1 (ko) | 1995-05-30 |
JPH07113011B2 (ja) | 1995-12-06 |
PT86093B (pt) | 1990-11-20 |
CA1296740C (en) | 1992-03-03 |
NO167382B (no) | 1991-07-22 |
NZ222427A (en) | 1989-06-28 |
HU197880B (en) | 1989-06-28 |
NO874627D0 (no) | 1987-11-06 |
CN1009088B (zh) | 1990-08-08 |
DK583887D0 (da) | 1987-11-06 |
EP0270843B1 (en) | 1991-03-06 |
ZA878217B (en) | 1988-04-28 |
IE872998L (en) | 1988-05-07 |
JPS63198660A (ja) | 1988-08-17 |
IL84364A (en) | 1991-08-16 |
DE3768449D1 (en) | 1991-04-11 |
CN87107599A (zh) | 1988-08-03 |
PT86093A (en) | 1987-12-01 |
HUT45475A (en) | 1988-07-28 |
PH24148A (en) | 1990-03-22 |
FI87923B (fi) | 1992-11-30 |
ES2036561T3 (es) | 1993-06-01 |
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