KR870008888A - 디하이드로-1h-피롤리진-3,5-(2h,6h)-디온을 제조하는 개선된 방법 - Google Patents
디하이드로-1h-피롤리진-3,5-(2h,6h)-디온을 제조하는 개선된 방법 Download PDFInfo
- Publication number
- KR870008888A KR870008888A KR870002527A KR870002527A KR870008888A KR 870008888 A KR870008888 A KR 870008888A KR 870002527 A KR870002527 A KR 870002527A KR 870002527 A KR870002527 A KR 870002527A KR 870008888 A KR870008888 A KR 870008888A
- Authority
- KR
- South Korea
- Prior art keywords
- lower alkyl
- dione
- acid
- dihydro
- pyrrolidin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Steroid Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (5)
- 3차 저급 알킬 아민의 존재하에 4-(하이드록시이미노) 헵탄디온산의 모노(저급 알킬)에스테르를 접촉 수소화하여 5-옥소-2-피롤티딘프로판산을 얻고 그 후에 환화제의 존재하에 5-옥소-2-피롤리딘프로판산을 가열하여 디하이드로-1H-피롤리진-3,5-(2H,6H)-디온을 얻는 개선점을 특징으로 하는, 4-(하이드록시이미노) 헵탄디온산의 에스테르를 접촉 수소화하고 결과의 생성물을 환화시켜 디하이드-1H-는피롤리진-3,5-(2H,6H)-디온을 얻는 단계로 구성되는 디하이드로-1H-피롤리진-3,5H-(2H,6H)-디온을 제조하는 방법.
- 제 1 항에 있어서, 3차 저급 알킬 아민이 C3-9를 포함하는 트리알킬 아민 그룹에서 선택된 것인 방법.
- 제 2 항에 있어서, 3차 저급 알킬 아민이 트리에틸 아민인 방법.
- 제 1 항에 있어서, 환화제가 무수 아세트산인 방법.
- 제 3 항에 있어서, 헵탄디온산의 모노(저급 알킬)에스테르가 모노메틸 헵탄디오에이트인 방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/842,702 US4663464A (en) | 1986-03-21 | 1986-03-21 | Process for the preparation of dihydro-1H-pyrrolizine-3,5-(2H,6H)-dione |
US842702 | 1986-03-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
KR870008888A true KR870008888A (ko) | 1987-10-21 |
Family
ID=25288045
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR870002527A KR870008888A (ko) | 1986-03-21 | 1987-03-20 | 디하이드로-1h-피롤리진-3,5-(2h,6h)-디온을 제조하는 개선된 방법 |
Country Status (17)
Country | Link |
---|---|
US (1) | US4663464A (ko) |
EP (1) | EP0238088B1 (ko) |
JP (1) | JPS62230784A (ko) |
KR (1) | KR870008888A (ko) |
AT (1) | ATE57929T1 (ko) |
AU (1) | AU586070B2 (ko) |
CA (1) | CA1280423C (ko) |
DE (1) | DE3765810D1 (ko) |
DK (1) | DK141987A (ko) |
ES (1) | ES2018661B3 (ko) |
FI (1) | FI871195A (ko) |
GR (1) | GR3001042T3 (ko) |
NO (1) | NO164297C (ko) |
NZ (1) | NZ219713A (ko) |
PH (1) | PH22822A (ko) |
PT (1) | PT84517B (ko) |
ZA (1) | ZA871307B (ko) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4977235A (en) * | 1989-02-23 | 1990-12-11 | Shell Oil Company | Polyarylate polymers |
US4914176A (en) * | 1989-03-17 | 1990-04-03 | Shell Oil Company | Poly(heterocyclic) polymers |
US5969833A (en) * | 1996-10-09 | 1999-10-19 | Tyco Submarine Systems Ltd. | Monitoring system using an optical side tone as a test signal |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5129484A (en) * | 1974-09-05 | 1976-03-12 | Juki Gosei Yakuhin Kogyo Kk | Deshiritsutoru 22 * 33pirijiru * pirorijin no seizoho |
US4372966A (en) * | 1980-09-15 | 1983-02-08 | Warner-Lambert Company | Use of dihydro-1H-pyrrolizine-3,5(2H,6H)-dione as a cognition activator |
US4581462A (en) * | 1983-08-25 | 1986-04-08 | The Upjohn Company | Pyrrolizidine-3-ones |
US4551470A (en) * | 1983-08-29 | 1985-11-05 | Warner-Lambert Company | Hexahydro-3,5-dioxo-1H-pyrrolizine-2-carboxylic acid and derivatives, and use for reversing electroconvulsive shock amnesia |
US4548947A (en) * | 1984-05-07 | 1985-10-22 | Warner-Lambert Company | 1-(Substituted-aryl)-dihydro-1H-pyrrolizine-3,5-[2H,6H-]diones and use for reversing amnesia |
US4563469A (en) * | 1984-07-20 | 1986-01-07 | Warner-Lambert Company | Derivatives of N-[2-(tetrahydro-3,5-dioxo-1H-pyrrolizin-7a(5H)-yl)ethyl]amine as cognition activators |
-
1986
- 1986-03-21 US US06/842,702 patent/US4663464A/en not_active Expired - Fee Related
-
1987
- 1987-02-18 CA CA000530033A patent/CA1280423C/en not_active Expired - Fee Related
- 1987-02-23 ZA ZA871307A patent/ZA871307B/xx unknown
- 1987-02-24 AU AU69192/87A patent/AU586070B2/en not_active Ceased
- 1987-03-17 PH PH35039A patent/PH22822A/en unknown
- 1987-03-18 FI FI871195A patent/FI871195A/fi not_active Application Discontinuation
- 1987-03-19 DK DK141987A patent/DK141987A/da not_active Application Discontinuation
- 1987-03-19 PT PT84517A patent/PT84517B/pt not_active IP Right Cessation
- 1987-03-20 NZ NZ219713A patent/NZ219713A/xx unknown
- 1987-03-20 AT AT87104088T patent/ATE57929T1/de not_active IP Right Cessation
- 1987-03-20 JP JP62064430A patent/JPS62230784A/ja active Pending
- 1987-03-20 KR KR870002527A patent/KR870008888A/ko not_active Application Discontinuation
- 1987-03-20 NO NO871174A patent/NO164297C/no unknown
- 1987-03-20 DE DE8787104088T patent/DE3765810D1/de not_active Expired - Fee Related
- 1987-03-20 ES ES87104088T patent/ES2018661B3/es not_active Expired - Lifetime
- 1987-03-20 EP EP87104088A patent/EP0238088B1/en not_active Expired - Lifetime
-
1990
- 1990-11-01 GR GR90400861T patent/GR3001042T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
NZ219713A (en) | 1989-06-28 |
DK141987A (da) | 1987-09-22 |
CA1280423C (en) | 1991-02-19 |
NO871174D0 (no) | 1987-03-20 |
ES2018661B3 (es) | 1991-05-01 |
FI871195A (fi) | 1987-09-22 |
US4663464A (en) | 1987-05-05 |
PT84517A (en) | 1987-04-01 |
DE3765810D1 (de) | 1990-12-06 |
NO871174L (no) | 1987-09-22 |
EP0238088A2 (en) | 1987-09-23 |
AU6919287A (en) | 1987-09-24 |
PH22822A (en) | 1989-01-19 |
ATE57929T1 (de) | 1990-11-15 |
NO164297C (no) | 1990-09-19 |
ZA871307B (en) | 1988-09-28 |
AU586070B2 (en) | 1989-06-29 |
JPS62230784A (ja) | 1987-10-09 |
EP0238088A3 (en) | 1989-02-22 |
EP0238088B1 (en) | 1990-10-31 |
GR3001042T3 (en) | 1992-01-20 |
PT84517B (pt) | 1989-11-10 |
NO164297B (no) | 1990-06-11 |
FI871195A0 (fi) | 1987-03-18 |
DK141987D0 (da) | 1987-03-19 |
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A201 | Request for examination | ||
E902 | Notification of reason for refusal | ||
E601 | Decision to refuse application |