KR870008845A - N-피리딜옥시페닐이소티오우레아의 제조방법 - Google Patents

N-피리딜옥시페닐이소티오우레아의 제조방법 Download PDF

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Publication number
KR870008845A
KR870008845A KR870002553A KR870002553A KR870008845A KR 870008845 A KR870008845 A KR 870008845A KR 870002553 A KR870002553 A KR 870002553A KR 870002553 A KR870002553 A KR 870002553A KR 870008845 A KR870008845 A KR 870008845A
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South Korea
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producing
alkyl
following structural
compound according
structural formula
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KR870002553A
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English (en)
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뷔거 만프레드
드라벡 조제프
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칼 에프·조르다
시바-가이기 코오포레이숀
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Publication of KR870008845A publication Critical patent/KR870008845A/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C07D213/643—2-Phenoxypyridines; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
    • A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Agronomy & Crop Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pyridine Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

내용 없음

Description

N-피리딜옥시페닐이소티오우레아의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (15)

  1. 하기 일반식(Ⅱ)의 피리딜옥시페닐티오우레아를 일반식(Ⅲ)의 알킬화제와 반응시키는 것으로 이루어지는 일반식(Ⅰ) 화합물의 제조방법:
    상기식에서,
    치환체 R1은 각각 독립적으로 할로겐, C1-C3알킬, 단일-또는 다수 할로겐화 C1-C3알킬기: 또는 -COOR7이고;
    R2,R3및 R7은 각각 독립적으로 C1-C5알킬이며, 단, R6이 3급 부틸이고 치환체 R1이 염소 및/또는 트리플루오로메틸인 경우, R2및 R3가 동시에 메틸일 수 없고;
    R4는 수소 또는 메틸이며;
    R5는 C1-C6알킬이고;
    R6는 C1-C12알킬, 단일 또는 다수 할로겐화 C1-C12알킬기, C1-C6알콕시, C1-C12알킬, C3-C8시클로알킬, 단일-또는 이(di) (C1-C3)알킬화 C3-C8시클로알킬기, C3-C8시클로알킬-C1-C4알킬, 또는 7 내지 10개의 탄소원자를 함유하는 다수고리 알킬라디칼이며;
    n은 0 내지 4이고;
    X는 이탈기임.
  2. 제 1 항에 있어서, 치환체 R1이 각각 독립적으로 불소, 염소 또는 단일-또는 다수할로겐화 C1-C3알킬기이고; R2및 R3이 각각 독립적으로 C1-C3알킬이며, 단, R6가 3급부틸이고 치환체 R1이 염소 및/또는 트리플루오로메틸인 경우, R2및 R3이 동시에 메틸은 아니며; R4가 수소이고; R5가 C1-C3알킬이며; R6이 C1-C8알킬, C1-C4알콕시, C1-C4알킬, C3-C6시클로알킬, 단일-또는 이(di) (C1-C|3)알킬화 C3-C6시클로알킬기, 또는 C3-C6시클로알킬-C1-C3알킬이고; 또 n이 1 또는 2인 일반식(Ⅰ) 화합물의 제조방법.
  3. 제 2 항에 있어서, 치환체 R1이 각각 독립적으로 염소 또는 CF2CFCl2이고; R2및 R3이 각각 독립적으로 메틸 또는 에틸이고, 단, R6이 3급 부틸이고 치환체 R1이 염소 및/또는 트리플루오로메틸인 경우, R2및 R3이 동시에 메틸은 아니며; R4가 수소이고; R5가 메틸이며; R6가 C1-C5알킬 또는 C3-C|6시클로알킬이고; n이 2인 일반식(Ⅰ) 화합물의 제조방법.
  4. 제 3 항에 있어서, 하기 구조식을 갖는 화합물의 제조방법.
  5. 제 2 항에 있어서, 하기 구조식을 갖는 화합물의 제조방법.
  6. 제 3 항에 있어서, 하기 구조식을 갖는 화합물의 제조방법.
  7. 제 3 항에 있어서, 하기 구조식을 갖는 화합물의 제조방법.
  8. 제 2 항에 있어서, 하기 구조식을 갖는 화합물의 제조방법.
  9. 제 3 항에 있어서, 하기 구조식을 갖는 화합물의 제조방법.
  10. 제 2 항에 있어서, 하기 구조식을 갖는 화합물의 제조방법.
  11. 제 3 항에 있어서, 하기 구조식을 갖는 화합물의 제조방법.
  12. 제 3 항에 있어서, 하기 구조식을 갖는 화합물의 제조방법.
  13. 제 3 항에 있어서, 하기 구조식을 갖는 화합물의 제조방법.
  14. 제 2 항에 있어서, 하기 구조식을 갖는 화합물의 제조방법.
  15. 제 2 항에 있어서, 하기 구조식을 갖는 화합물의 제조방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR870002553A 1986-03-19 1987-03-19 N-피리딜옥시페닐이소티오우레아의 제조방법 KR870008845A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH1107/86-4 1986-03-19
CH110786 1986-03-19
CH44287 1987-02-06
CH442/87-9 1987-02-06

Publications (1)

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KR870008845A true KR870008845A (ko) 1987-10-21

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ID=25684587

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KR870002553A KR870008845A (ko) 1986-03-19 1987-03-19 N-피리딜옥시페닐이소티오우레아의 제조방법

Country Status (8)

Country Link
US (1) US4866079A (ko)
EP (1) EP0239535A3 (ko)
KR (1) KR870008845A (ko)
AR (1) AR242784A1 (ko)
AU (1) AU590915B2 (ko)
BR (1) BR8701224A (ko)
CA (1) CA1244033A (ko)
IL (1) IL81895A (ko)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4931448A (en) * 1987-11-17 1990-06-05 Ici Americas Inc. Thiomidate insecticides
US4992453A (en) * 1987-11-17 1991-02-12 Ici Americas Inc. Certain thioimidate and amidine insecticides
US5045566A (en) * 1987-11-17 1991-09-03 Ici Americas Inc. Novel imidate insecticides
US4994488A (en) * 1988-10-31 1991-02-19 Ici Americas Inc. Novel imidate insecticides
US5066667A (en) * 1989-06-26 1991-11-19 Ciba-Geigy Corporation Thioxotetrazolines and insecticidal use thereof
FR2649011A1 (fr) * 1989-07-03 1991-01-04 Carilene Laboratoires Produit medicamenteux pour la revascularisation des tissus
EP0407346A3 (en) * 1989-07-07 1991-10-02 Ciba-Geigy Ag Aminopyridines
US6583157B2 (en) 1998-01-29 2003-06-24 Tularik Inc. Quinolinyl and benzothiazolyl modulators
WO1999038845A1 (en) 1998-01-29 1999-08-05 Tularik Inc. Ppar-gamma modulators
US7041691B1 (en) 1999-06-30 2006-05-09 Amgen Inc. Compounds for the modulation of PPARγ activity
US6653332B2 (en) 2000-05-03 2003-11-25 Tularik Inc. Combination therapeutic compositions and method of use
US20030171399A1 (en) * 2000-06-28 2003-09-11 Tularik Inc. Quinolinyl and benzothiazolyl modulators
US7223761B2 (en) * 2003-10-03 2007-05-29 Amgen Inc. Salts and polymorphs of a potent antidiabetic compound
AU2005221140A1 (en) * 2004-03-08 2005-09-22 Amgen Inc. Therapeutic modulation of PPAR (gamma) activity

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Publication number Priority date Publication date Assignee Title
US3931201A (en) * 1974-01-22 1976-01-06 The Dow Chemical Company Substituted pyridinyloxy(thio)phenyl -acetamides, -ureas and urea derivatives
DE3064249D1 (en) * 1979-07-03 1983-08-25 Ciba Geigy Ag Thio-urea derivatives and isothio-urea derivatives, process for their preparation, compositions containing these compounds and their use in combating pests
US4328247A (en) * 1979-09-19 1982-05-04 Ciba-Geigy Corporation Phenoxyphenylisothioureas, production thereof and use thereof in pest control, and phenoxyphenylthioureas as intermediates for the production of the phenoxyphenylisothioureas and use thereof in pest control
BE888179A (fr) * 1981-03-30 1981-09-30 Ciba Geigy Phenoxyphenylisothiourees, procede pour leur preparation et leur application dans la lutte antiparasitaire ainsi que phenoxyphenylthiourees comme produits intermediaires pour la preparation des phenoxyphenyliqothiourees ainsi que leur application dans la lutte antiparatitaire
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DE3337828A1 (de) * 1982-10-21 1984-04-26 Ciba-Geigy Ag, Basel Benzoylphenylthioharnstoffe

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EP0239535A3 (de) 1989-09-27
US4866079A (en) 1989-09-12
CA1244033A (en) 1988-11-01
BR8701224A (pt) 1987-12-22
AR242784A1 (es) 1993-05-31
AU590915B2 (en) 1989-11-23
IL81895A (en) 1991-06-30
AU7015387A (en) 1987-09-24
IL81895A0 (en) 1987-10-20
EP0239535A2 (de) 1987-09-30

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