KR870001126A - 응고에 중립인 친수성 유리섬유 - Google Patents

응고에 중립인 친수성 유리섬유 Download PDF

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Publication number
KR870001126A
KR870001126A KR1019860005109A KR860005109A KR870001126A KR 870001126 A KR870001126 A KR 870001126A KR 1019860005109 A KR1019860005109 A KR 1019860005109A KR 860005109 A KR860005109 A KR 860005109A KR 870001126 A KR870001126 A KR 870001126A
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glass fiber
reagent
glass
layer
glass fibers
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KR1019860005109A
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KR930006326B1 (ko
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비엘린거 한스
프라이택 헬뮤트
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뵈링거 만하임 게엠베하
다움 포우퀘트
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Publication of KR870001126A publication Critical patent/KR870001126A/ko
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Publication of KR930006326B1 publication Critical patent/KR930006326B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C25/00—Surface treatment of fibres or filaments made from glass, minerals or slags
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0076—Chemical modification of the substrate
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D39/00—Filtering material for liquid or gaseous fluids
    • B01D39/02—Loose filtering material, e.g. loose fibres
    • B01D39/06—Inorganic material, e.g. asbestos fibres, glass beads or fibres
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D39/00—Filtering material for liquid or gaseous fluids
    • B01D39/14—Other self-supporting filtering material ; Other filtering material
    • B01D39/20—Other self-supporting filtering material ; Other filtering material of inorganic material, e.g. asbestos paper, metallic filtering material of non-woven wires
    • B01D39/2003—Glass or glassy material
    • B01D39/2017—Glass or glassy material the material being filamentary or fibrous
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C25/00—Surface treatment of fibres or filaments made from glass, minerals or slags
    • C03C25/10—Coating
    • C03C25/24—Coatings containing organic materials
    • C03C25/40—Organo-silicon compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2239/00—Aspects relating to filtering material for liquid or gaseous fluids
    • B01D2239/04—Additives and treatments of the filtering material
    • B01D2239/0414—Surface modifiers, e.g. comprising ion exchange groups
    • B01D2239/0421—Rendering the filter material hydrophilic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2239/00—Aspects relating to filtering material for liquid or gaseous fluids
    • B01D2239/04—Additives and treatments of the filtering material
    • B01D2239/0471—Surface coating material
    • B01D2239/0492—Surface coating material on fibres
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2239/00—Aspects relating to filtering material for liquid or gaseous fluids
    • B01D2239/12—Special parameters characterising the filtering material
    • B01D2239/1233—Fibre diameter
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2913—Rod, strand, filament or fiber
    • Y10T428/2933—Coated or with bond, impregnation or core
    • Y10T428/2962—Silane, silicone or siloxane in coating
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2913—Rod, strand, filament or fiber
    • Y10T428/2933—Coated or with bond, impregnation or core
    • Y10T428/2964—Artificial fiber or filament
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2913—Rod, strand, filament or fiber
    • Y10T428/298—Physical dimension
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Geology (AREA)
  • Materials Engineering (AREA)
  • Organic Chemistry (AREA)
  • General Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Geochemistry & Mineralogy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Glass Compositions (AREA)
  • Surface Treatment Of Glass Fibres Or Filaments (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • External Artificial Organs (AREA)

Abstract

내용 없음.

Description

응고에 중립인 친수성 유리섬유
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 시험스트립의 구성을 나타내는 도면.
제2도는 프로트롬시간에 대한 퀵크%를 나타낸 도면.
* 도면의 주요부분에 대한 부호의 설명
1 : 폴리스티렌운반체호일 2 : 접착제
3 : 나이론망 4 : 본 발명에 따른 유리섬유털
5 : 산화매트릭스 6 : 시약매트릭스
7 : 폴리카르본산이 덮힌 호일

Claims (18)

  1. 유리섬유 위에 다음 구조에 따른 실란이 결합된 응고에 중성인 친수성 유리섬유
    상기식에서 R1은 C2내지 C6가 포함된 알킬렌기이며, X는 히드록실기, 알콕시기는 하나 또는 그 이상의 히드록실기 또는 아미노산으로 임의로 치환된 알콕시기 또는 펩티드잔기이고, 그리고 R3′는 저급알킬기 또는 이웃하는 기의 실리콘원자 또는 유리표면과의 산소다리이다.
  2. 제1항에 있어서, 1내지 30분자 두께의 실란층인 유리섬유.
  3. 제2항에 있어서, 4내지 12분자 두께의 실란층인 유리섬유.
  4. 제1항에 있어서, 실제로 앞서 제시 및 예시한 유리섬유.
  5. 제1항에 있어서, 깨끗한 유리섬유가 일반식의 실란과 반응한 유리섬유 생산공정
    상기식에서 R1은 C2내지 C6를 포함한 알킬렌기이며, R2는 C6까지를 포함한 알콕시기이며 R3는 C6까지 포함한 알킬기, 알콜시기이고, 여기서 옥시란기는 가수분해, 알코올가수분해에 의해 또는 아미노산 또는 펩티드와 반응하여 X기로 전환된다.
  6. 제5항에 있어서, 반응은 수용액상태에서 산성촉매의 존재하에서 수행되며 히드록실기는 X기로써 얻어진다는 공정.
  7. 제5항에 있어서, 반응은 무수매질에서 수행된 공정.
  8. 실제로 상기에 제시하고 예시한 바와 같은 제1항에 따른 유리섬유의 생산공정.
  9. 제5항 내지 제8항 중의 어느 하나에 따른 공정에 의해 생산된 유리섬유.
  10. 유리섬유가 제1항내지 제4항중의 어느 항에 따른 것이고, 평균직경 0.2내지 0.5μ 및 0.1내지 0.5ｇ/㎤의 밀도를 지닌 유리섬유층으로 이루어진 직혈학적 시험을 위한 혈액으로부터 혈장분리를 위한 시약.
  11. 제10항에 있어서, 유리섬유가 평균직경이 0.5내지 2.5μ인 시약.
  12. 제10항 또는 제11항에 있어서, 칼럼의 윗부분은 혈액응용방법을 위해 제공되며 칼럼의 끝부분은 혈장 제거방번을 위해 제공된 칼럼에서 층을 이룬 섬유시약.
  13. 제10항 또는 제11항에 있어서, 유리섬유층이 유리섬유종이 또는 유리섬유털로 이루어지며 응고지표 검출을 위한 진단시약부분인 시약.
  14. 제13항에 있어서, 유리섬유층은 다발층 진단시약의 최초의 층인 시약.
  15. 제13항에 있어서, 순서대로 하나 또는 그 이상의 시약층과 흡수접촉되거나 또는 접촉될 수 있는 혈장 전달층과 흡수접촉된 유리섬유층 시약.
  16. 실제 상기에 제시하고 예시한 바와 같은 지혈학적 시험용으로 혈액으로부터 혈장분리를 위한 시약.
  17. 제1항 내지 제4항 중의 어느 하나에 있어서, 지혈학적 검사를 위한 유리섬유의 사용.
  18. 제1항 내지 제4항 중의 어느 하나에 있어서, 지혈학적 검사를 위하는 시험생산을 위한 유리섬유의 사용.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019860005109A 1985-07-04 1986-06-26 응고에 중립인 친수성 유리섬유 KR930006326B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19853523969 DE3523969A1 (de) 1985-07-04 1985-07-04 Gerinnungsneutrale, hydrophile glasfasern
DEP3523969.7 1985-07-04
DE3523969.7 1985-07-04

Publications (2)

Publication Number Publication Date
KR870001126A true KR870001126A (ko) 1987-03-11
KR930006326B1 KR930006326B1 (ko) 1993-07-14

Family

ID=6274979

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Application Number Title Priority Date Filing Date
KR1019860005109A KR930006326B1 (ko) 1985-07-04 1986-06-26 응고에 중립인 친수성 유리섬유

Country Status (13)

Country Link
US (1) US4786603A (ko)
EP (1) EP0208218B1 (ko)
JP (1) JPS627650A (ko)
KR (1) KR930006326B1 (ko)
AT (1) ATE50760T1 (ko)
AU (1) AU560350B2 (ko)
CA (1) CA1262220A (ko)
DE (2) DE3523969A1 (ko)
DK (1) DK167918B1 (ko)
ES (1) ES2000311A6 (ko)
NO (1) NO171971C (ko)
PT (1) PT82908B (ko)
ZA (1) ZA864832B (ko)

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DE3516579A1 (de) * 1984-11-19 1986-05-22 Boehringer Mannheim Gmbh, 6800 Mannheim Gerinnungstest auf teststreifen
DE3610429A1 (de) * 1986-03-27 1987-10-01 Boehringer Mannheim Gmbh Gerinnungsneutrale, hydrophile glasfasern
US4749614A (en) * 1986-04-10 1988-06-07 International Business Machines Corporation Process for coating fibers, use thereof, and product
DE3616496A1 (de) * 1986-05-16 1987-11-19 Boehringer Mannheim Gmbh Analyseelement zur bestimmung von gerinnungsparametern
US4849340A (en) * 1987-04-03 1989-07-18 Cardiovascular Diagnostics, Inc. Reaction system element and method for performing prothrombin time assay
US5110727A (en) * 1987-04-03 1992-05-05 Cardiovascular Diagnostics, Inc. Method for performing coagulation assays accurately, rapidly and simply, using dry chemical reagents and paramagnetic particles
US5208147A (en) * 1988-07-21 1993-05-04 Radiometer A/S Means for measuring a characteristic in a sample fluid
US5135716A (en) * 1989-07-12 1992-08-04 Kingston Diagnostics, L.P. Direct measurement of HDL cholesterol via dry chemistry strips
US5360545A (en) * 1989-09-12 1994-11-01 Pall Corporation Filter for obtaining platelets
US5258126A (en) * 1989-09-12 1993-11-02 Pall Corporation Method for obtaining platelets
US5798261A (en) * 1989-10-31 1998-08-25 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Distributed pore chemistry in porous organic polymers
US5141806A (en) * 1989-10-31 1992-08-25 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Microporous structure with layered interstitial surface treatment, and method and apparatus for preparation thereof
US5266219A (en) * 1989-12-28 1993-11-30 Pall Corporation Device and method for separating plasma from blood
US5118428A (en) * 1990-11-13 1992-06-02 Quidel Method to remove red blood cells from whole blood samples
EP0497204B1 (en) * 1991-01-28 2001-04-18 Matsushita Electric Industrial Co., Ltd. Medical member and method of manufacturing the same
DE69225743T2 (de) * 1991-03-14 1998-09-24 Matsushita Electric Ind Co Ltd Oberflächenbehandeltes Material für Bekleidung
US5186843A (en) * 1991-07-22 1993-02-16 Ahlstrom Filtration, Inc. Blood separation media and method for separating plasma from whole blood
US5460974A (en) * 1992-10-13 1995-10-24 Miles Inc. Method of assaying whole blood for HDL cholesterol
US5766552A (en) * 1993-04-20 1998-06-16 Actimed Laboratories, Inc. Apparatus for red blood cell separation
US5660798A (en) * 1993-04-20 1997-08-26 Actimed Laboratories, Inc. Apparatus for red blood cell separation
US5652148A (en) * 1993-04-20 1997-07-29 Actimed Laboratories, Inc. Method and apparatus for red blood cell separation
WO1996003194A1 (en) * 1994-07-28 1996-02-08 Pall Corporation Fibrous web and process of preparing same
US5582907A (en) * 1994-07-28 1996-12-10 Pall Corporation Melt-blown fibrous web
US6238578B1 (en) 1996-12-09 2001-05-29 Sherwood Services Ag Method for dispensing separator gel in a blood collection tube

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CA473440A (en) * 1945-11-13 1951-05-08 Fiberglass Canada Limited Composite bodies of glass fibres and resins
US2683097A (en) * 1951-04-17 1954-07-06 Owens Corning Fiberglass Corp Coating glass fibers with unsaturated polysiloxanolate and article produced thereby
US2946701A (en) * 1957-11-12 1960-07-26 Dow Corning Method of treating glass with epoxysilanes and their epoxy-amine adducts, and the articles made thereby
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JPS608745B2 (ja) * 1978-02-14 1985-03-05 三洋化成工業株式会社 免疫活性物質−つや消しガラス複合体，その製造法及び該複合体を含有してなる測定試薬
US4246107A (en) * 1978-03-06 1981-01-20 Asahi Kasei Kogyo Kabushiki Kaisha Separation of lymphocytes from lymphocyte-containing suspension by filtration
DE3029579C2 (de) * 1980-08-05 1985-12-12 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren und Mittel zur Abtrennung von Plasma oder Serum aus Vollblut
JPS5810056A (ja) * 1981-07-10 1983-01-20 株式会社クラレ 血液浄化装置
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Publication number Publication date
NO171971B (no) 1993-02-15
PT82908B (pt) 1988-05-27
DE3523969A1 (de) 1987-01-08
DK167918B1 (da) 1994-01-03
CA1262220A (en) 1989-10-10
DK313686A (da) 1987-01-05
NO862626L (no) 1987-01-05
JPH0475860B2 (ko) 1992-12-02
ATE50760T1 (de) 1990-03-15
AU560350B2 (en) 1987-04-02
EP0208218A2 (de) 1987-01-14
NO862626D0 (no) 1986-06-30
JPS627650A (ja) 1987-01-14
DE3669308D1 (de) 1990-04-12
PT82908A (de) 1986-08-01
ZA864832B (en) 1987-03-25
EP0208218A3 (en) 1987-09-02
US4786603A (en) 1988-11-22
ES2000311A6 (es) 1988-02-16
NO171971C (no) 1993-05-26
KR930006326B1 (ko) 1993-07-14
DK313686D0 (da) 1986-07-01
EP0208218B1 (de) 1990-03-07
AU5937986A (en) 1987-01-08

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