KR860002185B1 - A-21978c 사이클릭 펩티드 유도체의 제조방법 - Google Patents

A-21978c 사이클릭 펩티드 유도체의 제조방법 Download PDF

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Publication number
KR860002185B1
KR860002185B1 KR1019830002222A KR830002222A KR860002185B1 KR 860002185 B1 KR860002185 B1 KR 860002185B1 KR 1019830002222 A KR1019830002222 A KR 1019830002222A KR 830002222 A KR830002222 A KR 830002222A KR 860002185 B1 KR860002185 B1 KR 860002185B1
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KR
South Korea
Prior art keywords
acid
formula
nuclei
amino
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
KR1019830002222A
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English (en)
Korean (ko)
Other versions
KR840005076A (ko
Inventor
데보노 마누엘
Original Assignee
일라이 릴리 앤드 캄파니
아더 알. 웨일
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 일라이 릴리 앤드 캄파니, 아더 알. 웨일 filed Critical 일라이 릴리 앤드 캄파니
Publication of KR840005076A publication Critical patent/KR840005076A/ko
Application granted granted Critical
Publication of KR860002185B1 publication Critical patent/KR860002185B1/ko
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/045—Actinoplanes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/62—Streptosporangium
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/19—Antibiotic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1019830002222A 1982-05-21 1983-05-19 A-21978c 사이클릭 펩티드 유도체의 제조방법 Expired KR860002185B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US380498 1982-05-21
US06/380,498 US4399067A (en) 1982-05-21 1982-05-21 Derivatives of A-21978C cyclic peptides
US380.498 1982-05-21

Publications (2)

Publication Number Publication Date
KR840005076A KR840005076A (ko) 1984-11-03
KR860002185B1 true KR860002185B1 (ko) 1986-12-24

Family

ID=23501401

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019830002222A Expired KR860002185B1 (ko) 1982-05-21 1983-05-19 A-21978c 사이클릭 펩티드 유도체의 제조방법

Country Status (15)

Country Link
US (1) US4399067A (enExample)
KR (1) KR860002185B1 (enExample)
AT (1) AT380022B (enExample)
CA (1) CA1215043A (enExample)
DD (1) DD209810A5 (enExample)
DK (1) DK220983A (enExample)
EG (1) EG16042A (enExample)
ES (1) ES522561A0 (enExample)
FI (1) FI831746L (enExample)
GR (1) GR79259B (enExample)
HU (1) HU192955B (enExample)
PH (1) PH21382A (enExample)
PL (1) PL242096A1 (enExample)
PT (1) PT76701B (enExample)
RO (1) RO86721B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA883887B (en) * 1987-06-10 1990-02-28 Lilly Co Eli Chromatographic purification process
US4977083A (en) * 1988-04-11 1990-12-11 Eli Lilly And Company Processes for preparing A54145 compounds
US5140101A (en) * 1990-11-21 1992-08-18 Bristol-Myers Squibb Company Antiviral antibiotic BU-4344V
US5256548A (en) * 1990-11-21 1993-10-26 Bristol-Myers Squibb Company Antiviral antibiotic BU-4344V
WO2001044271A2 (en) * 1999-12-15 2001-06-21 Cubist Pharmaceuticals, Inc. Daptomycin analogs and their use as antibacterial agents
KR20020063228A (ko) * 1999-12-15 2002-08-01 큐비스트 파마슈티컬즈 인코포레이티드 항균제로서 리포펩티드
US6911525B2 (en) * 1999-12-15 2005-06-28 Cubist Pharmaceuticals, Inc. Lipopeptides as antibacterial agents
EP1423137B1 (en) * 2001-08-06 2009-04-29 Cubist Pharmaceuticals, Inc. Lipopeptide stereoisomers, methods for preparing same, and useful intermediates
EP1932853A1 (en) 2001-08-06 2008-06-18 Cubist Pharmaceutical Inc. Novel depsipeptides and process for preparing same
US20060004185A1 (en) * 2004-07-01 2006-01-05 Leese Richard A Peptide antibiotics and peptide intermediates for their prepartion
RU2512396C2 (ru) * 2008-12-22 2014-04-10 Кьюбист Фармасьютикалз, Инк. Новые противобактериальные средства для лечения грамположительных инфекций
AR074874A1 (es) * 2008-12-23 2011-02-16 Biosource Pharm Inc Composiciones antibioticas para el tratamiento de infecciones gram negativas. metodo. uso. compuesto.
US8415307B1 (en) 2010-06-23 2013-04-09 Biosource Pharm, Inc. Antibiotic compositions for the treatment of gram negative infections
US11174288B2 (en) 2016-12-06 2021-11-16 Northeastern University Heparin-binding cationic peptide self-assembling peptide amphiphiles useful against drug-resistant bacteria

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3150059A (en) * 1962-12-26 1964-09-22 Lilly Co Eli Penicillin deacylation via actinoplanaceae fermentation
US4208403A (en) * 1978-10-16 1980-06-17 Eli Lilly And Company A-21978 Antibiotics and process for their production
US4297277A (en) * 1979-12-13 1981-10-27 Eli Lilly And Company Derivatives of A-30912B nucleus
US4293486A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of S31794/F-1 nucleus
US4293489A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912A nucleus
US4293482A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company A-30912A Nucleus
US4289692A (en) * 1979-12-13 1981-09-15 Eli Lilly And Company Derivatives of A-30912D nucleus
US4293484A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912H nucleus

Also Published As

Publication number Publication date
ES8407012A1 (es) 1984-09-01
DK220983A (da) 1983-11-22
ES522561A0 (es) 1984-09-01
PT76701B (en) 1986-03-27
ATA178383A (de) 1985-08-15
CA1215043A (en) 1986-12-09
FI831746A7 (fi) 1983-11-22
RO86721A (ro) 1985-04-17
HU192955B (en) 1987-08-28
EG16042A (en) 1986-12-30
US4399067A (en) 1983-08-16
DD209810A5 (de) 1984-05-23
PT76701A (en) 1983-06-01
PH21382A (en) 1987-10-15
AT380022B (de) 1986-03-25
GR79259B (enExample) 1984-10-22
RO86721B (ro) 1985-05-01
KR840005076A (ko) 1984-11-03
FI831746L (fi) 1983-11-22
FI831746A0 (fi) 1983-05-18
PL242096A1 (en) 1984-07-02
DK220983D0 (da) 1983-05-18

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US6573084B1 (en) Process for the deacylation of cyclic lipopeptides
KR860002185B1 (ko) A-21978c 사이클릭 펩티드 유도체의 제조방법
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Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19830519

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Patent event date: 19860725

Patent event code: PE09021S01D

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Comment text: Decision on Publication of Application

Patent event code: PG16051S01I

Patent event date: 19861121

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

Patent event code: PE07011S01D

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Patent event date: 19870305