KR850000246A - 하이드로탈시트상 결정구조를 갖는 화합물의 수열 처리된 생성물의 제조방법 및 이의 조성물 및 이의 이용 - Google Patents

하이드로탈시트상 결정구조를 갖는 화합물의 수열 처리된 생성물의 제조방법 및 이의 조성물 및 이의 이용 Download PDF

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KR850000246A
KR850000246A KR1019840003635A KR840003635A KR850000246A KR 850000246 A KR850000246 A KR 850000246A KR 1019840003635 A KR1019840003635 A KR 1019840003635A KR 840003635 A KR840003635 A KR 840003635A KR 850000246 A KR850000246 A KR 850000246A
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compound
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water
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시게오(외 1) 미야다
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마쓰시마 요시오
교오와 가가꾸 고오교 가부시끼 가이샤
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
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    • C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
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    • C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
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    • C07C59/235—Saturated compounds containing more than one carboxyl group
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    • C07C59/255—Tartaric acid
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    • C01P2006/60—Optical properties, e.g. expressed in CIELAB-values

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Abstract

내용 없음.

Description

하이드로탈시드상 결정구조를 갖는 화합물의 수열 처리된 생성물의 제조방법 및 이의 조성물 및 이의 이용
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
도면은 투약 후 경과한 시간에 대한 세륨철분 수준을 도시한 그래프이다.

Claims (9)

  1. 하기 일반식(Ⅰ)로 표시되는 하이드로탈시트상 결정구조를 갖는 화합물을 수용액 매질중에서 약 100내지 200℃의 온도로 열처리하여 형성된 수열처리 생성물의 헤모글로빈과 세륨철분 수준중의 하나 이상을 증가시키는, 유효량(1)과 약학적으로 허용가능한 희석제 또는 담체(2)로 구성됨을 특징으로 하는 헤모글로빈과 세륨철분 수준중의 하나 이상을 증가시키는 조성물.
  2. 제1항에 있어서, 일반식(Ⅰ)는 화합물이 하기 일반식(Ⅰ)′로 표시됨을 특징으로 하는 조성물.
  3. 제1또는 2항에 있어서, x는 2.5≤x〈8로 표시됨을 특징으로 하는 조성물.
  4. 제1항에 있어서, 화합물(Ⅰ)의 함량이 조성물의 전체 무개에 대해 약 30내지 95％임을 특징으로 하는 조성물.
  5. 하기 일반식(Ⅰ)로 표시되는 하이드로탈시드상 결정구조를 갖는 화합물을 수용액 매질중에서 약100내지 200℃의 온도로 열처리하여 형성된 수열처리 생성물의 헤모글로빈과 세륨철분중의 하나 이상을 증가시키는 유효량을 경구에 투여함을 특징으로 하는 헤모글로빈과 세륨철분 수준의 하나 이상을 증가시키는 방법.
  6. 제5항에 있어서, 일반식(Ⅰ)의 화합물이 하기 일반식(Ⅰ)′로 표시됨을 특징으로 하는 조성물.
  7. 제5 또는 6항에 있어서, 수열처리된 생성물의 이른 1인당 1일 복용량이 약 50내지 2,000㎎임을 특징으로 하는 방법.
  8. 제5 또는 6항에 있어서, 빈혈증 환자를 치료함을 특징으로 하는 방법.
  9. 수용성2가의 철염수용성 또는 수용성 2가의 철염과 수용성 마그네슘 화합물 수용액(a)과 수용성 알루미늄 화합물 수용액 또는 수용성 알루미늄 화합물과 수용성 3가의 철염 수용액(b)을 알카리성 PH 예를 들면, 약 6 이상, 바람직하기로는 약 8내지 12에서,n가의 음이온 An-을 형성할 수 있는 화합물의 존재 또는 부재중에서, 바람직하기로는 산화방지 대기중에서(c) 반응시켜 하기 일반식(Ⅰ)로 표시되는 하이드로탈시트상 결정구조를 갖는 화합물을 형성하고(1), 생성된 일반식(1)의 화합물을 수용액 매질 중에서 약100내지 200℃의 온도로 수열처리(2)함을 특징으로 하는 철분 부족증 치료에 유용한 수열처리 생성물의 제조방법.
    ※ 참고사항 ： 최초출원 내용에 의하여 공개하는 것임.
KR1019840003635A 1983-06-27 1984-06-27 하이드로탈시트상 결정구조를 갖는 화합물의 수열처리된 생성물의 제조방법 KR890000209B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP114,364/83 1983-06-27
JP58114364A JPS606619A (ja) 1983-06-27 1983-06-27 鉄分欠乏症処置剤及びその製法
JP114364/83 1983-06-27

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KR850000246A true KR850000246A (ko) 1985-02-26
KR890000209B1 KR890000209B1 (ko) 1989-03-10

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US (1) US4629626A (ko)
EP (1) EP0134936A1 (ko)
JP (1) JPS606619A (ko)
KR (1) KR890000209B1 (ko)
CA (1) CA1227920A (ko)
ES (1) ES8506189A1 (ko)

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JPS606619A (ja) 1985-01-14
KR890000209B1 (ko) 1989-03-10
EP0134936A1 (en) 1985-03-27
ES533722A0 (es) 1985-07-01
CA1227920A (en) 1987-10-13
JPH0532370B2 (ko) 1993-05-14
ES8506189A1 (es) 1985-07-01
US4629626A (en) 1986-12-16

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