KR830010067A - 진통작용을 가진 가용성 화합물의 제조방법 - Google Patents
진통작용을 가진 가용성 화합물의 제조방법 Download PDFInfo
- Publication number
- KR830010067A KR830010067A KR1019820002319A KR820002319A KR830010067A KR 830010067 A KR830010067 A KR 830010067A KR 1019820002319 A KR1019820002319 A KR 1019820002319A KR 820002319 A KR820002319 A KR 820002319A KR 830010067 A KR830010067 A KR 830010067A
- Authority
- KR
- South Korea
- Prior art keywords
- analgesic action
- soluble compounds
- lysine
- surgery
- water
- Prior art date
Links
- 230000000202 analgesic effect Effects 0.000 title claims 2
- 150000001875 compounds Chemical class 0.000 title claims 2
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 claims 3
- KDXKERNSBIXSRK-UHFFFAOYSA-N lysine Chemical compound NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 2
- 238000001356 surgical procedure Methods 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 1
- 206010019233 Headaches Diseases 0.000 claims 1
- 235000019766 L-Lysine Nutrition 0.000 claims 1
- 239000004472 Lysine Substances 0.000 claims 1
- 208000002193 Pain Diseases 0.000 claims 1
- 208000005298 acute pain Diseases 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 238000001816 cooling Methods 0.000 claims 1
- 238000002682 general surgery Methods 0.000 claims 1
- 231100000869 headache Toxicity 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 230000000399 orthopedic effect Effects 0.000 claims 1
- 201000008482 osteoarthritis Diseases 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
- G01S3/00—Direction-finders for determining the direction from which infrasonic, sonic, ultrasonic, or electromagnetic waves, or particle emission, not having a directional significance, are being received
- G01S3/78—Direction-finders for determining the direction from which infrasonic, sonic, ultrasonic, or electromagnetic waves, or particle emission, not having a directional significance, are being received using electromagnetic waves other than radio waves
- G01S3/782—Systems for determining direction or deviation from predetermined direction
- G01S3/783—Systems for determining direction or deviation from predetermined direction using amplitude comparison of signals derived from static detectors or detector systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Electromagnetism (AREA)
- Remote Sensing (AREA)
- Radar, Positioning & Navigation (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Photometry And Measurement Of Optical Pulse Characteristics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (2)
- 같은 분자량의 L-라이신(Ⅱ)(또는 DL-라이신)과 5-(파리-클로로벤조일)-1,4-디메틸-피롤-2-초산(Ⅰ)을 물 또는 물과 알코올의 혼합물존재하에서, 0°-100℃온도 범위내에서 반응시켜 생성되는 염을 농축 또는 용액을 냉각시켜서 혹은 그것을 비용매 처리시켜서, 분리함을 특징으로 하는 구조식(A)화합물의 제조방법.
- 진통작용을 가졌으며, 악성종양, 일반외과수술, 구강수술, 정형외과수술, 골관절염에서 생긴 급만성 통증 또는 각종 원인에서 오는 두통을 치료하는데 적당한 약제학적인 조성물.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56-69781 | 1981-05-09 | ||
IT21949A/81 | 1981-05-26 | ||
IT21949/81A IT1137229B (it) | 1981-05-26 | 1981-05-26 | Composto solubile ad attivita' analgesica |
JP56-99993 | 1981-06-26 | ||
JP57-17237 | 1982-02-05 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR830010067A true KR830010067A (ko) | 1983-12-26 |
KR860000292B1 KR860000292B1 (ko) | 1986-03-26 |
Family
ID=11189271
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR828202319A KR860000292B1 (ko) | 1981-05-09 | 1982-05-26 | 태양광 방향센서 |
Country Status (10)
Country | Link |
---|---|
JP (1) | JPS57200359A (ko) |
KR (1) | KR860000292B1 (ko) |
BE (1) | BE893039A (ko) |
CA (1) | CA1171421A (ko) |
DE (1) | DE3219605A1 (ko) |
ES (1) | ES512510A0 (ko) |
FR (1) | FR2506766A1 (ko) |
GB (1) | GB2098989B (ko) |
IT (1) | IT1137229B (ko) |
PT (1) | PT74949B (ko) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1210673B (it) * | 1982-02-26 | 1989-09-20 | Medosan Ind Biochimi | Antinfiammatoria amidi pirrolacetiche ad attivita' |
IT1197688B (it) * | 1983-07-29 | 1988-12-06 | Medosan Ind Biochimi | Attivita' antiflogistica,analgesica,antipiretica ed antiaggregante piastrinica di 1-metil-5-metilbenzoilpirrol-2-acetamido acetanilidi |
DE3328401A1 (de) * | 1983-08-05 | 1985-02-21 | Merckle GmbH, 7902 Blaubeuren | Injizierbare loesung zur behandlung von entzuendungen |
US4873340A (en) * | 1986-05-29 | 1989-10-10 | Syntex (U.S.A.) Inc. | Process for preparing 5-aroyl-1,2-dihydro-3H-pyrrolo[1,2-A]pyrrole-1,1-dicarboxylates |
US4988822A (en) * | 1986-05-29 | 1991-01-29 | Syntex (U.S.A.) Inc. | Intermediates for preparing 5-aroyl-1,2-dihydro-3H-pyrrolo(1,2-A)pyrrole-1,1-dicarboxylates |
GB8819569D0 (en) * | 1988-08-17 | 1988-09-21 | Dow Corning Ltd | Emulsions for treating fibrous materials |
KR100898501B1 (ko) * | 2007-09-03 | 2009-05-21 | 윤주평 | Cds소자를 이용한 태양광 추적장치 |
KR101091936B1 (ko) * | 2009-08-31 | 2011-12-08 | 에스디엔 주식회사 | 일사량 센서를 이용한 태양광 입사각 검출장치 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4213905A (en) * | 1979-06-25 | 1980-07-22 | Mcneilab, Inc. | Preparation of 5-aroyl-1-loweralkylpyrrole-2-acetic acid salts |
-
1981
- 1981-05-26 IT IT21949/81A patent/IT1137229B/it active
-
1982
- 1982-04-30 BE BE0/207975A patent/BE893039A/fr not_active IP Right Cessation
- 1982-05-19 GB GB8214547A patent/GB2098989B/en not_active Expired
- 1982-05-24 PT PT74949A patent/PT74949B/pt unknown
- 1982-05-25 CA CA000403645A patent/CA1171421A/en not_active Expired
- 1982-05-25 ES ES512510A patent/ES512510A0/es active Granted
- 1982-05-25 FR FR8209026A patent/FR2506766A1/fr active Pending
- 1982-05-25 DE DE19823219605 patent/DE3219605A1/de not_active Withdrawn
- 1982-05-26 JP JP57089594A patent/JPS57200359A/ja active Pending
- 1982-05-26 KR KR828202319A patent/KR860000292B1/ko active
Also Published As
Publication number | Publication date |
---|---|
KR860000292B1 (ko) | 1986-03-26 |
IT1137229B (it) | 1986-09-03 |
IT8121949A0 (it) | 1981-05-26 |
PT74949B (en) | 1983-12-23 |
CA1171421A (en) | 1984-07-24 |
BE893039A (fr) | 1982-08-16 |
DE3219605A1 (de) | 1982-12-23 |
JPS57200359A (en) | 1982-12-08 |
PT74949A (en) | 1982-06-01 |
ES8302653A1 (es) | 1983-02-01 |
GB2098989B (en) | 1984-10-10 |
GB2098989A (en) | 1982-12-01 |
ES512510A0 (es) | 1983-02-01 |
FR2506766A1 (fr) | 1982-12-03 |
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