KR840002046B1 - 세팔로스포린의 제조방법 - Google Patents

세팔로스포린의 제조방법 Download PDF

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Publication number
KR840002046B1
KR840002046B1 KR1019810002403A KR810002403A KR840002046B1 KR 840002046 B1 KR840002046 B1 KR 840002046B1 KR 1019810002403 A KR1019810002403 A KR 1019810002403A KR 810002403 A KR810002403 A KR 810002403A KR 840002046 B1 KR840002046 B1 KR 840002046B1
Authority
KR
South Korea
Prior art keywords
acid
formula
compound
salts
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
KR1019810002403A
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English (en)
Korean (ko)
Other versions
KR830006310A (ko
Inventor
앨런 버지즈 데이빗
로렌스 던 죠오지
Original Assignee
스미스 클라인 코포레이션
리차드 도미니크 포기오
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 스미스 클라인 코포레이션, 리차드 도미니크 포기오 filed Critical 스미스 클라인 코포레이션
Publication of KR830006310A publication Critical patent/KR830006310A/ko
Application granted granted Critical
Publication of KR840002046B1 publication Critical patent/KR840002046B1/ko
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1019810002403A 1980-07-03 1981-07-02 세팔로스포린의 제조방법 Expired KR840002046B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/165,822 US4308267A (en) 1980-07-03 1980-07-03 7-[2-Alkoxyimino-2-(amino-thiazole)acetamido]-3-[1-(sulfaminoalkly)tetrazolthiomethyl]cephalosporins
US165822 1980-07-03

Publications (2)

Publication Number Publication Date
KR830006310A KR830006310A (ko) 1983-09-20
KR840002046B1 true KR840002046B1 (ko) 1984-11-06

Family

ID=22600626

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019810002403A Expired KR840002046B1 (ko) 1980-07-03 1981-07-02 세팔로스포린의 제조방법

Country Status (23)

Country Link
US (1) US4308267A (enExample)
EP (1) EP0043713B1 (enExample)
JP (1) JPS5745189A (enExample)
KR (1) KR840002046B1 (enExample)
AR (1) AR228606A1 (enExample)
AT (1) ATE9585T1 (enExample)
AU (1) AU547942B2 (enExample)
CA (1) CA1151150A (enExample)
DE (1) DE3166321D1 (enExample)
DK (1) DK286981A (enExample)
ES (1) ES503622A0 (enExample)
FI (1) FI66876C (enExample)
GR (1) GR74363B (enExample)
HU (1) HU185934B (enExample)
IE (1) IE51365B1 (enExample)
IL (1) IL63206A (enExample)
NO (1) NO812268L (enExample)
NZ (1) NZ197573A (enExample)
PH (1) PH17670A (enExample)
PT (1) PT73292B (enExample)
YU (1) YU162481A (enExample)
ZA (1) ZA814484B (enExample)
ZW (1) ZW15181A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4526977A (en) * 1981-10-07 1985-07-02 American Home Products Corporation 2-(3-Amino-5-isoxazolyl)-2-oxyimino-acetic acids

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4171362A (en) * 1975-10-30 1979-10-16 Smithkline Corporation 7-Acylamino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporins antibacterial compositions containing them and methods of treating bacterial infections with them
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
JPS52125188A (en) 1976-04-14 1977-10-20 Takeda Chem Ind Ltd Cephalosporin derivatives and their preparation
US4066762A (en) * 1976-07-12 1978-01-03 Smithkline Corporation Derivatives of 7-(2-substituted-2-hydroxyiminoacetamido)-3-(1-substituted tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
MC1259A1 (fr) 1978-05-30 1980-01-14 Hoffmann La Roche Derives acyles
US4220761A (en) * 1978-09-12 1980-09-02 Fujisawa Pharmaceutical Co., Ltd. 7-[Substituted oximinoacetamido]-3-[hydroxy alkyltetrazolo]cephalosporin derivatives

Also Published As

Publication number Publication date
AR228606A1 (es) 1983-03-30
YU162481A (en) 1983-06-30
NO812268L (no) 1982-01-04
GR74363B (enExample) 1984-06-28
FI66876B (fi) 1984-08-31
DK286981A (da) 1982-01-04
AU7234381A (en) 1982-01-07
IE51365B1 (en) 1986-12-10
EP0043713A1 (en) 1982-01-13
IE811481L (en) 1982-01-03
PT73292B (en) 1982-07-22
HU185934B (en) 1985-04-28
AU547942B2 (en) 1985-11-14
EP0043713B1 (en) 1984-09-26
ZA814484B (en) 1982-07-28
ATE9585T1 (de) 1984-10-15
IL63206A (en) 1986-09-30
FI812046L (fi) 1982-01-04
KR830006310A (ko) 1983-09-20
PT73292A (en) 1981-07-01
ZW15181A1 (en) 1981-09-29
ES8203908A1 (es) 1982-04-01
PH17670A (en) 1984-11-02
DE3166321D1 (en) 1984-10-31
ES503622A0 (es) 1982-04-01
IL63206A0 (en) 1981-09-13
FI66876C (fi) 1984-12-10
JPS5745189A (en) 1982-03-13
CA1151150A (en) 1983-08-02
NZ197573A (en) 1984-09-28
US4308267A (en) 1981-12-29

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