KR830006425A - 매크로리드의 제조방법 - Google Patents

매크로리드의 제조방법 Download PDF

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Publication number
KR830006425A
KR830006425A KR1019810002384A KR810002384A KR830006425A KR 830006425 A KR830006425 A KR 830006425A KR 1019810002384 A KR1019810002384 A KR 1019810002384A KR 810002384 A KR810002384 A KR 810002384A KR 830006425 A KR830006425 A KR 830006425A
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KR
South Korea
Prior art keywords
manufacturing
tylactone
nitrogen
carbon
inorganic salts
Prior art date
Application number
KR1019810002384A
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English (en)
Other versions
KR840001954B1 (ko
Inventor
헨리 발쯔 리챠드
토마스 세노 유겐
Original Assignee
아더 알. 웨일
일라이 릴리 앤드 캄파니
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 아더 알. 웨일, 일라이 릴리 앤드 캄파니 filed Critical 아더 알. 웨일
Publication of KR830006425A publication Critical patent/KR830006425A/ko
Application granted granted Critical
Publication of KR840001954B1 publication Critical patent/KR840001954B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/08—Oxygen as only ring hetero atoms containing a hetero ring of at least seven ring members, e.g. zearalenone, macrolide aglycons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • C12R2001/54—Streptomyces fradiae
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces
    • Y10S435/896—Streptomyces fradiae

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

내용 없음

Description

매크로리드의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 클로로포름 중에서의 타이락톤의 적외선 흡수 스펙트럼.

Claims (2)

  1. 스트렙토마이세스 프라디아에(Streptomyces fradiae) NRRL 12188 또는 이의 타이락톤 생산변이체 또는 재결합체를 액침 호기성 발효조건하에 탄소, 질소 및 무기염의 동화원이 함유된 배지내에서 배양하여 타이락톤을 생산한 다음 이어서 임의로 에스테르화함을 특징으로 하여 타이락톤 또는 이의 에스테르유도체의 제조 방법.
  2. 스트렙토마이세스 프라디아에 NRRL 12188 및 탄소, 질소 및 무기염의 동화원을 함유함을 특징으로 하는 배양배지.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019810002384A 1980-07-02 1981-07-01 매크로리드의 제조방법 KR840001954B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US162977 1980-07-02
US06/162,977 US4366247A (en) 1980-07-02 1980-07-02 Process for preparing tylactone

Publications (2)

Publication Number Publication Date
KR830006425A true KR830006425A (ko) 1983-09-24
KR840001954B1 KR840001954B1 (ko) 1984-10-26

Family

ID=22587920

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019810002384A KR840001954B1 (ko) 1980-07-02 1981-07-01 매크로리드의 제조방법

Country Status (24)

Country Link
US (1) US4366247A (ko)
EP (1) EP0043280B1 (ko)
JP (1) JPS5743692A (ko)
KR (1) KR840001954B1 (ko)
AU (1) AU7238581A (ko)
BG (1) BG35749A3 (ko)
CA (1) CA1171009A (ko)
CS (1) CS221839B2 (ko)
DD (1) DD202047A5 (ko)
DE (1) DE3162648D1 (ko)
DK (1) DK292681A (ko)
ES (1) ES8205018A1 (ko)
FI (1) FI812065L (ko)
GB (1) GB2079279B (ko)
GR (1) GR74938B (ko)
HU (1) HU189515B (ko)
IE (1) IE51361B1 (ko)
IL (1) IL63221A (ko)
NZ (1) NZ197585A (ko)
PL (1) PL231943A1 (ko)
PT (1) PT73288B (ko)
SU (1) SU1069631A3 (ko)
YU (1) YU162181A (ko)
ZA (1) ZA814463B (ko)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4423148A (en) * 1982-07-02 1983-12-27 Eli Lilly And Company Process for producing 20-dihydro-20-deoxy-23-de(mycinosyloxy)tylosin
JPS59181294A (ja) * 1983-03-30 1984-10-15 Satoshi Omura 抗生物質ｐｔｌ−４４８とその誘導体およびそれらの製造方法
US5284757A (en) * 1989-01-12 1994-02-08 Ajinomoto Company, Inc. Process for producing l-arginine by fermentation with brevibacterium or corynebacterium
US5698420A (en) * 1995-12-05 1997-12-16 Pfizer Inc. Preparation of 4-deoxy-O-mycaminosyltylonolide
CA2197524A1 (en) * 1996-02-22 1997-08-22 Bradley Stuart Dehoff Polyketide synthase genes
KR100914251B1 (ko) 2007-06-27 2009-08-26 이화여자대학교 산학협력단 신규한 올리보실 틸락톤 및 그 제조 방법
MD1180Z (ro) * 2017-03-02 2018-03-31 Институт Физиологии И Санокреатологии Академии Наук Молдовы Procedeu de stimulare a formării reflexelor condiţionate în perioada diminuării funcţiilor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3178341A (en) * 1960-06-27 1965-04-13 Lilly Co Eli Antibiotics tylosin and desmycosin and derivatives thereof
US3326759A (en) * 1962-07-19 1967-06-20 Lilly Co Eli Antibiotics macrocin and lactenocin
US3344024A (en) * 1963-04-17 1967-09-26 American Cyanamid Co Antibiotic am-684 and method of production
BE667952A (ko) * 1964-08-05
US4161523A (en) * 1972-11-15 1979-07-17 Schering Corporation Rosamicin esters, acid addition salts and methods for production thereof
GB1587685A (en) * 1977-03-09 1981-04-08 Microbial Chem Res Found Macrolactone derivatives and their production

Also Published As

Publication number Publication date
EP0043280B1 (en) 1984-03-14
YU162181A (en) 1983-09-30
PT73288A (en) 1981-07-01
CA1171009A (en) 1984-07-17
AU7238581A (en) 1982-01-07
EP0043280A1 (en) 1982-01-06
GB2079279A (en) 1982-01-20
NZ197585A (en) 1983-11-30
ES503565A0 (es) 1982-05-16
IL63221A0 (en) 1981-10-30
ES8205018A1 (es) 1982-05-16
US4366247A (en) 1982-12-28
FI812065L (fi) 1982-01-03
DD202047A5 (de) 1983-08-24
KR840001954B1 (ko) 1984-10-26
IE51361B1 (en) 1986-12-10
DK292681A (da) 1982-01-03
PL231943A1 (ko) 1982-10-11
GB2079279B (en) 1984-08-22
ZA814463B (en) 1983-02-23
GR74938B (ko) 1984-07-12
JPS5743692A (en) 1982-03-11
SU1069631A3 (ru) 1984-01-23
DE3162648D1 (en) 1984-04-19
CS221839B2 (en) 1983-04-29
PT73288B (en) 1982-07-22
IE811462L (en) 1982-01-02
HU189515B (en) 1986-07-28
IL63221A (en) 1985-03-31
BG35749A3 (en) 1984-06-15

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