KR20250012203A - 인간 도메인을 갖는 항-b 세포 성숙화 항원 키메라성 항원 수용체 - Google Patents

인간 도메인을 갖는 항-b 세포 성숙화 항원 키메라성 항원 수용체 Download PDF

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KR20250012203A
KR20250012203A KR1020257001390A KR20257001390A KR20250012203A KR 20250012203 A KR20250012203 A KR 20250012203A KR 1020257001390 A KR1020257001390 A KR 1020257001390A KR 20257001390 A KR20257001390 A KR 20257001390A KR 20250012203 A KR20250012203 A KR 20250012203A
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leu
gly
heavy chain
ala
human
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Korean (ko)
Inventor
제임스 엔 코첸더퍼
노리스 램
네이선 트린클라인
캐서린 이 해리스
쉘리 포스 알드레드
스호턴 빔 판
Original Assignee
더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈
테네오바이오, 인코포레이티드
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Application filed by 더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈, 테네오바이오, 인코포레이티드 filed Critical 더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈
Publication of KR20250012203A publication Critical patent/KR20250012203A/ko
Pending legal-status Critical Current

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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/48—Blood cells, e.g. leukemia or lymphoma
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    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
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    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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KR1020257001390A 2017-06-30 2018-06-28 인간 도메인을 갖는 항-b 세포 성숙화 항원 키메라성 항원 수용체 Pending KR20250012203A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201762527556P 2017-06-30 2017-06-30
US62/527,556 2017-06-30
PCT/US2018/039917 WO2019006072A1 (en) 2017-06-30 2018-06-28 CHIMERIC ANTIGENIC RECEPTORS TO ANTIGEN OF MATURATION OF LYMPHOCYTES B WITH HUMAN DOMAINS
KR1020207002752A KR102757010B1 (ko) 2017-06-30 2018-06-28 인간 도메인을 갖는 항-b 세포 성숙화 항원 키메라성 항원 수용체

Related Parent Applications (1)

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KR1020207002752A Division KR102757010B1 (ko) 2017-06-30 2018-06-28 인간 도메인을 갖는 항-b 세포 성숙화 항원 키메라성 항원 수용체

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KR20250012203A true KR20250012203A (ko) 2025-01-23

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KR1020207002752A Active KR102757010B1 (ko) 2017-06-30 2018-06-28 인간 도메인을 갖는 항-b 세포 성숙화 항원 키메라성 항원 수용체
KR1020257001390A Pending KR20250012203A (ko) 2017-06-30 2018-06-28 인간 도메인을 갖는 항-b 세포 성숙화 항원 키메라성 항원 수용체

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US (2) US20200138865A1 (enExample)
EP (2) EP3645568B1 (enExample)
JP (4) JP7288405B2 (enExample)
KR (2) KR102757010B1 (enExample)
CN (1) CN111094345B (enExample)
AU (2) AU2018291128B2 (enExample)
ES (1) ES2928296T3 (enExample)
IL (1) IL271597B2 (enExample)
SG (1) SG11201913175TA (enExample)
WO (1) WO2019006072A1 (enExample)

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