KR20240171182A - 암 화학요법을 강화시키기 위한 조성물 및 방법 - Google Patents

암 화학요법을 강화시키기 위한 조성물 및 방법 Download PDF

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Publication number
KR20240171182A
KR20240171182A KR1020247039365A KR20247039365A KR20240171182A KR 20240171182 A KR20240171182 A KR 20240171182A KR 1020247039365 A KR1020247039365 A KR 1020247039365A KR 20247039365 A KR20247039365 A KR 20247039365A KR 20240171182 A KR20240171182 A KR 20240171182A
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South Korea
Prior art keywords
nutritional supplement
selenium
fish oil
tumor
tumor cells
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Pending
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KR1020247039365A
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English (en)
Korean (ko)
Inventor
호운 사이먼 샤
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호운 사이먼 샤
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Publication of KR20240171182A publication Critical patent/KR20240171182A/ko
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/282Platinum compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4409Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/04Sulfur, selenium or tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/60Fish, e.g. seahorses; Fish eggs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Epoxy Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
KR1020247039365A 2017-06-13 2018-06-13 암 화학요법을 강화시키기 위한 조성물 및 방법 Pending KR20240171182A (ko)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US201762519093P 2017-06-13 2017-06-13
US201762519096P 2017-06-13 2017-06-13
US62/519,093 2017-06-13
US62/519,096 2017-06-13
US201762595002P 2017-12-05 2017-12-05
US62/595,002 2017-12-05
US201862670275P 2018-05-11 2018-05-11
US62/670,275 2018-05-11
KR1020207000865A KR102736425B1 (ko) 2017-06-13 2018-06-13 암 화학요법을 강화시키기 위한 조성물 및 방법
PCT/US2018/037274 WO2018231943A2 (en) 2017-06-13 2018-06-13 Compositions and methods for enhancing cancer chemotherapy

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020207000865A Division KR102736425B1 (ko) 2017-06-13 2018-06-13 암 화학요법을 강화시키기 위한 조성물 및 방법

Publications (1)

Publication Number Publication Date
KR20240171182A true KR20240171182A (ko) 2024-12-06

Family

ID=64658652

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020247039365A Pending KR20240171182A (ko) 2017-06-13 2018-06-13 암 화학요법을 강화시키기 위한 조성물 및 방법
KR1020207000865A Active KR102736425B1 (ko) 2017-06-13 2018-06-13 암 화학요법을 강화시키기 위한 조성물 및 방법

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020207000865A Active KR102736425B1 (ko) 2017-06-13 2018-06-13 암 화학요법을 강화시키기 위한 조성물 및 방법

Country Status (9)

Country Link
US (2) US10905725B2 (https=)
EP (1) EP3638247A4 (https=)
JP (3) JP7788129B2 (https=)
KR (2) KR20240171182A (https=)
CN (1) CN111556754A (https=)
CA (1) CA3066713A1 (https=)
IL (1) IL271328A (https=)
TW (2) TW202535473A (https=)
WO (1) WO2018231943A2 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL265786B (en) 2016-10-03 2022-09-01 Houn Simon Hsia Materials and methods for increasing radiotherapy against cancer
EP3638269B1 (en) 2017-06-13 2025-12-17 Houn Simon Hsia Nutritional supplement for enhancing cancer radiotherapy
US10905725B2 (en) * 2017-06-13 2021-02-02 Houn Simon Hsia Compositions and methods for enhancing cancer chemotherapy
US12029765B2 (en) 2017-06-13 2024-07-09 Houn Simon Hsia Compositions and methods for treating cancer
IL271327B2 (en) 2017-06-13 2024-11-01 Simon Hsia Houn Compositions for increasing tumor sensitivity to hyperthermia therapy
US20220175850A1 (en) * 2019-04-01 2022-06-09 Houn Simon Hsia Compositions and methods for cancer therapy
AU2021324673B2 (en) * 2020-08-10 2025-07-24 Houn Simon Hsia Compositions and methods for treating viral infection

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4348483A (en) 1981-01-23 1982-09-07 Universal Foods Corporation Method for the production of chromium yeast
US4569836A (en) 1981-08-27 1986-02-11 Gordon Robert T Cancer treatment by intracellular hyperthermia
CA2010511A1 (en) 1989-03-01 1990-09-01 Roberto L. Ceriani Method of enhancing cancer therapy by administration of unsaturated fatty acids
NZ248605A (en) 1993-05-28 1994-12-22 Abbott Lab Enteral nutritional product comprising protein and fat
US20020010144A1 (en) 1994-04-29 2002-01-24 Robert Sobol Enhancing the sensitivity of tumor cells to therapies
US5976548A (en) 1994-11-08 1999-11-02 Viva America Marketing, Inc. Nutritional supplement composition and use
US6077828A (en) * 1996-04-25 2000-06-20 Abbott Laboratories Method for the prevention and treatment of cachexia and anorexia
US6440464B1 (en) 1996-06-10 2002-08-27 Viva Life Science Nutritive composition for cardiovascular health containing fish oil, garlic, rutin, capsaicin, selenium, vitamins and juice concentrates
US6197295B1 (en) * 1996-09-25 2001-03-06 Viva America Marketing Corporation Dietary supplementation with, and methods for administration of yeast-derived selenium product
US5810888A (en) 1997-06-26 1998-09-22 Massachusetts Institute Of Technology Thermodynamic adaptive phased array system for activating thermosensitive liposomes in targeted drug delivery
CA2339473A1 (en) 1998-08-04 2000-02-17 John V. Kosbab Nutrient and therapeutic compositions for the treatment of cancer
US7569551B2 (en) 2000-02-25 2009-08-04 The University Of British Columbia Chemo- and radiation-sensitization of cancer by antisense TRPM-2 oligodeoxynucleotides
US20050080468A1 (en) 2001-03-26 2005-04-14 Lawrence C. Christman Methods and apparatus for treating diseased tissue
EP1438971A4 (en) 2001-10-25 2005-01-12 Ttc Co Ltd IMMUNE AMPLIFIERS IN THERAPEUTIC THERAPY IN CANCER
NZ533737A (en) 2002-01-11 2006-02-24 Matthias Rath A nutrient pharmaceutical formulation comprising polyphenols and use in treatment of cancer
US20040087490A1 (en) 2002-09-20 2004-05-06 Troup John P. Nutritional compositions
AU2002951833A0 (en) 2002-10-02 2002-10-24 Novogen Research Pty Ltd Compositions and therapeutic methods invloving platinum complexes
US7744930B2 (en) 2002-11-22 2010-06-29 Shaklee Corporation Compositions, methods and kits for enhancing weight loss while inhibiting loss of lean body mass
US8663679B2 (en) 2004-04-29 2014-03-04 Abbott Laboratories Compositions for improving breast health in women
US9107864B2 (en) 2004-06-07 2015-08-18 Qu Biologics Inc. Tissue targeted antigenic activation of the immune response to treat cancers
US20060088574A1 (en) 2004-10-25 2006-04-27 Manning Paul B Nutritional supplements
US20070116802A1 (en) 2005-11-23 2007-05-24 Carl Germano High quality caloric composition
US8017147B2 (en) 2008-04-07 2011-09-13 Mazed Mohammad A Nutritional supplement for the prevention of cardiovascular disease, alzheimer's disease, diabetes, and regulation and reduction of blood sugar and insulin resistance
US20090110674A1 (en) 2007-10-24 2009-04-30 Loizou Nicos C Health supplement
WO2009157759A1 (en) 2008-06-23 2009-12-30 N.V. Nutricia Nutritional composition for improving the mammalian immune system
EP3011843A1 (en) 2008-09-19 2016-04-27 Nestec S.A. Nutritional support of the immune system during anti-cancer treatment
US8257694B2 (en) 2009-05-14 2012-09-04 Product Partners, Llc Nutritional compositions for reducing oxidative damage
KR20120065276A (ko) 2009-05-29 2012-06-20 뉴 챕터, 인코포레이티드. 지질 조성을 조정하기 위한 조성물 및 방법
KR101275724B1 (ko) 2009-12-09 2013-06-17 한국전자통신연구원 단일 기판 집적 회로 장치 및 그 제조 방법
WO2011094579A2 (en) 2010-01-29 2011-08-04 New Chapter Inc. Mushroom compositions and methods for making and using
JP5882889B2 (ja) * 2010-03-15 2016-03-09 国立大学法人 岡山大学 抗腫瘍剤
US20120010688A1 (en) 2010-07-09 2012-01-12 Lamb Karl J Implantable conductive element and method of use inhyperthermic treatment
US9669053B2 (en) 2010-07-26 2017-06-06 Chemotherapeutics, Llc Compositions and methods for enhancing the effectiveness of systemic, HIPEC, IP, and related cancer treatments
WO2012122295A2 (en) 2011-03-07 2012-09-13 Ned Biosystems, Inc. Treatment for pancreatic adenocarcinoma and other cancers of epithelial origin
WO2014054884A1 (ko) 2012-10-05 2014-04-10 연세대학교 산학협력단 민감화 물질을 포함하는 온열 치료용 조성물
US9072768B2 (en) 2013-01-22 2015-07-07 Kibow Biotech, Inc. Composition and method for increasing effectiveness of radiation or chemotherapy
US9107947B2 (en) 2013-01-31 2015-08-18 The Penn State Research Foundation Anti-cancer compositions and methods
WO2014159851A2 (en) 2013-03-13 2014-10-02 The Board Of Regents Of The University Of Texas System Novel low density lipoprotein nanocarriers for targeted delevery of omega-3 polyunsaturated fatty acids to cancer
US20140294795A1 (en) * 2013-03-28 2014-10-02 Houn Simon Hsia Nutritional Composition
MX370055B (es) 2013-04-22 2019-11-29 Smartfish As Uso de una composición que comprende aceite de pescado y jugo para el tratamiento y/o postratamiento de cáncer.
SG11201600657RA (en) 2013-07-31 2016-02-26 Meiji Co Ltd Nutritional composition for inhibiting growth of tumor
EP3033091B1 (en) 2013-08-16 2022-09-07 Versitech Limited Probiotic composition and use thereof in the prevention and treatment of hepatocellular carcinoma
US20170246136A1 (en) 2014-09-24 2017-08-31 OliVentures, Inc. Pharmaceutical product, medical food or dietary supplement for preventing cancer and inflammatory diseases
CN105641000A (zh) 2015-06-01 2016-06-08 深圳市康道生物有限公司 一种含灰树花提取物的抗肿瘤组合物及其制备方法
JP7411327B2 (ja) 2015-11-18 2024-01-11 サイバーグ・コンサルティング・リミテッド・ライアビリティ・カンパニー 天然抽出物を含有する組成物、ならびに皮膚および毛髪に対するその使用
CN105617358A (zh) 2015-12-29 2016-06-01 广州市戴菊科技发展有限公司 一种具有抗肿瘤功能的医用食品及其制备方法
JP6376186B2 (ja) 2016-08-04 2018-08-22 トヨタ自動車株式会社 サスペンションメンバ
IL265786B (en) 2016-10-03 2022-09-01 Houn Simon Hsia Materials and methods for increasing radiotherapy against cancer
CN106822560A (zh) 2017-04-07 2017-06-13 湖北工程学院 药物组合物及其制备方法
US10905725B2 (en) * 2017-06-13 2021-02-02 Houn Simon Hsia Compositions and methods for enhancing cancer chemotherapy
EP3638269B1 (en) 2017-06-13 2025-12-17 Houn Simon Hsia Nutritional supplement for enhancing cancer radiotherapy

Also Published As

Publication number Publication date
EP3638247A2 (en) 2020-04-22
IL271328A (en) 2020-01-30
US10905725B2 (en) 2021-02-02
CN111556754A (zh) 2020-08-18
JP7788129B2 (ja) 2025-12-18
TW201906633A (zh) 2019-02-16
TW202535473A (zh) 2025-09-16
KR20200079229A (ko) 2020-07-02
WO2018231943A2 (en) 2018-12-20
CA3066713A1 (en) 2018-12-20
US20190134102A1 (en) 2019-05-09
US12036246B2 (en) 2024-07-16
EP3638247A4 (en) 2021-03-03
JP2026026381A (ja) 2026-02-16
JP2023115357A (ja) 2023-08-18
KR102736425B1 (ko) 2024-11-28
US20210252076A1 (en) 2021-08-19
WO2018231943A3 (en) 2019-02-28
JP2020523370A (ja) 2020-08-06

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