KR20240109239A - 아세틸화 시알산 글리코클러스터 및 감염성 질환을 치료하기 위한 이의 용도 - Google Patents

아세틸화 시알산 글리코클러스터 및 감염성 질환을 치료하기 위한 이의 용도 Download PDF

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Publication number
KR20240109239A
KR20240109239A KR1020247011675A KR20247011675A KR20240109239A KR 20240109239 A KR20240109239 A KR 20240109239A KR 1020247011675 A KR1020247011675 A KR 1020247011675A KR 20247011675 A KR20247011675 A KR 20247011675A KR 20240109239 A KR20240109239 A KR 20240109239A
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KR
South Korea
Prior art keywords
acetylated
glycocluster
sialic acid
formula
cov
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
KR1020247011675A
Other languages
English (en)
Korean (ko)
Inventor
데이비드 알스틴스
스테판 빈센트
Original Assignee
위니베르시트카솔리끄드루뱅
유니베르시테 드 나무르 에이에스비엘
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 위니베르시트카솔리끄드루뱅, 유니베르시테 드 나무르 에이에스비엘 filed Critical 위니베르시트카솔리끄드루뱅
Publication of KR20240109239A publication Critical patent/KR20240109239A/ko
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135Compounds containing heavy metals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/545Heterocyclic compounds
    • A61K47/546Porphyrines; Porphyrine with an expanded ring system, e.g. texaphyrine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26Acyclic or carbocyclic radicals, substituted by hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
KR1020247011675A 2021-09-10 2022-09-09 아세틸화 시알산 글리코클러스터 및 감염성 질환을 치료하기 위한 이의 용도 Pending KR20240109239A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21195975.4 2021-09-10
EP21195975 2021-09-10
PCT/EP2022/075109 WO2023036932A1 (en) 2021-09-10 2022-09-09 Acetylated sialic acid glycoclusters and their uses for treating infectious diseases

Publications (1)

Publication Number Publication Date
KR20240109239A true KR20240109239A (ko) 2024-07-10

Family

ID=77710644

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020247011675A Pending KR20240109239A (ko) 2021-09-10 2022-09-09 아세틸화 시알산 글리코클러스터 및 감염성 질환을 치료하기 위한 이의 용도

Country Status (7)

Country Link
US (1) US20250134921A1 (https=)
EP (1) EP4398940A1 (https=)
JP (1) JP2024533417A (https=)
KR (1) KR20240109239A (https=)
CN (1) CN118613285A (https=)
CA (1) CA3231261A1 (https=)
WO (1) WO2023036932A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN120192635B (zh) * 2025-05-26 2025-08-12 杭州之江有机硅化工有限公司 一种机械互锁环氧树脂聚合物及其制备方法和应用

Also Published As

Publication number Publication date
JP2024533417A (ja) 2024-09-12
CA3231261A1 (en) 2023-03-16
US20250134921A1 (en) 2025-05-01
CN118613285A (zh) 2024-09-06
WO2023036932A1 (en) 2023-03-16
EP4398940A1 (en) 2024-07-17

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