JP2024533417A - アセチル化シアル酸グリコクラスターおよび感染性疾患を治療するためのその使用 - Google Patents

アセチル化シアル酸グリコクラスターおよび感染性疾患を治療するためのその使用 Download PDF

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JP2024533417A
JP2024533417A JP2024515553A JP2024515553A JP2024533417A JP 2024533417 A JP2024533417 A JP 2024533417A JP 2024515553 A JP2024515553 A JP 2024515553A JP 2024515553 A JP2024515553 A JP 2024515553A JP 2024533417 A JP2024533417 A JP 2024533417A
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Japan
Prior art keywords
glycocluster
sialic acid
acetylated sialic
acetylated
cov
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Pending
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JP2024515553A
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Japanese (ja)
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JP2024533417A5 (https=
Inventor
アルスティーンス，デイビッド
ヴィンセント，ステファン
Original Assignee
ユニヴェルシテ カソリーク デ ルーヴァン
ユニヴェルシテ デ ナミュール
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Publication of JP2024533417A publication Critical patent/JP2024533417A/ja
Publication of JP2024533417A5 publication Critical patent/JP2024533417A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/545—Heterocyclic compounds
    • A61K47/546—Porphyrines; Porphyrine with an expanded ring system, e.g. texaphyrine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
JP2024515553A 2021-09-10 2022-09-09 アセチル化シアル酸グリコクラスターおよび感染性疾患を治療するためのその使用 Pending JP2024533417A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21195975.4 2021-09-10
EP21195975 2021-09-10
PCT/EP2022/075109 WO2023036932A1 (en) 2021-09-10 2022-09-09 Acetylated sialic acid glycoclusters and their uses for treating infectious diseases

Publications (2)

Publication Number Publication Date
JP2024533417A true JP2024533417A (ja) 2024-09-12
JP2024533417A5 JP2024533417A5 (https=) 2025-09-08

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ID=77710644

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024515553A Pending JP2024533417A (ja) 2021-09-10 2022-09-09 アセチル化シアル酸グリコクラスターおよび感染性疾患を治療するためのその使用

Country Status (7)

Country Link
US (1) US20250134921A1 (https=)
EP (1) EP4398940A1 (https=)
JP (1) JP2024533417A (https=)
KR (1) KR20240109239A (https=)
CN (1) CN118613285A (https=)
CA (1) CA3231261A1 (https=)
WO (1) WO2023036932A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN120192635B (zh) * 2025-05-26 2025-08-12 杭州之江有机硅化工有限公司 一种机械互锁环氧树脂聚合物及其制备方法和应用

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Publication number Publication date
CA3231261A1 (en) 2023-03-16
US20250134921A1 (en) 2025-05-01
CN118613285A (zh) 2024-09-06
WO2023036932A1 (en) 2023-03-16
EP4398940A1 (en) 2024-07-17
KR20240109239A (ko) 2024-07-10

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