CA3231261A1 - Acetylated sialic acid glycoclusters and their uses for treating infectious diseases - Google Patents

Acetylated sialic acid glycoclusters and their uses for treating infectious diseases Download PDF

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Publication number
CA3231261A1
CA3231261A1 CA3231261A CA3231261A CA3231261A1 CA 3231261 A1 CA3231261 A1 CA 3231261A1 CA 3231261 A CA3231261 A CA 3231261A CA 3231261 A CA3231261 A CA 3231261A CA 3231261 A1 CA3231261 A1 CA 3231261A1
Authority
CA
Canada
Prior art keywords
acetylated
glycocluster
sialic acid
cov
sars
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3231261A
Other languages
English (en)
French (fr)
Inventor
David ALSTEENS
Stephane Vincent
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite Catholique de Louvain UCL
Facultes Universitaires Notre Dame de la Paix
Original Assignee
Universite Catholique de Louvain UCL
Facultes Universitaires Notre Dame de la Paix
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite Catholique de Louvain UCL, Facultes Universitaires Notre Dame de la Paix filed Critical Universite Catholique de Louvain UCL
Publication of CA3231261A1 publication Critical patent/CA3231261A1/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135Compounds containing heavy metals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/545Heterocyclic compounds
    • A61K47/546Porphyrines; Porphyrine with an expanded ring system, e.g. texaphyrine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26Acyclic or carbocyclic radicals, substituted by hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
CA3231261A 2021-09-10 2022-09-09 Acetylated sialic acid glycoclusters and their uses for treating infectious diseases Pending CA3231261A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21195975.4 2021-09-10
EP21195975 2021-09-10
PCT/EP2022/075109 WO2023036932A1 (en) 2021-09-10 2022-09-09 Acetylated sialic acid glycoclusters and their uses for treating infectious diseases

Publications (1)

Publication Number Publication Date
CA3231261A1 true CA3231261A1 (en) 2023-03-16

Family

ID=77710644

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3231261A Pending CA3231261A1 (en) 2021-09-10 2022-09-09 Acetylated sialic acid glycoclusters and their uses for treating infectious diseases

Country Status (7)

Country Link
US (1) US20250134921A1 (https=)
EP (1) EP4398940A1 (https=)
JP (1) JP2024533417A (https=)
KR (1) KR20240109239A (https=)
CN (1) CN118613285A (https=)
CA (1) CA3231261A1 (https=)
WO (1) WO2023036932A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN120192635A (zh) * 2025-05-26 2025-06-24 杭州之江有机硅化工有限公司 一种机械互锁环氧树脂聚合物及其制备方法和应用

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN120192635A (zh) * 2025-05-26 2025-06-24 杭州之江有机硅化工有限公司 一种机械互锁环氧树脂聚合物及其制备方法和应用

Also Published As

Publication number Publication date
JP2024533417A (ja) 2024-09-12
US20250134921A1 (en) 2025-05-01
CN118613285A (zh) 2024-09-06
WO2023036932A1 (en) 2023-03-16
EP4398940A1 (en) 2024-07-17
KR20240109239A (ko) 2024-07-10

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