KR20240045351A - 연골 손상 및 관절염 치료 방법 및 조성물 - Google Patents

연골 손상 및 관절염 치료 방법 및 조성물 Download PDF

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Publication number
KR20240045351A
KR20240045351A KR1020247009753A KR20247009753A KR20240045351A KR 20240045351 A KR20240045351 A KR 20240045351A KR 1020247009753 A KR1020247009753 A KR 1020247009753A KR 20247009753 A KR20247009753 A KR 20247009753A KR 20240045351 A KR20240045351 A KR 20240045351A
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South Korea
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KR1020247009753A
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English (en)
Korean (ko)
Inventor
크리스틴 존슨
요르크 골트한
첼레스테 슈코티
이고어 포스티아어
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노파르티스 아게
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Publication of KR20240045351A publication Critical patent/KR20240045351A/ko
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020247009753A 2016-11-14 2017-11-13 연골 손상 및 관절염 치료 방법 및 조성물 Pending KR20240045351A (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201662421534P 2016-11-14 2016-11-14
US62/421,534 2016-11-14
US201762560301P 2017-09-19 2017-09-19
US62/560,301 2017-09-19
PCT/IB2017/057081 WO2018087727A1 (en) 2016-11-14 2017-11-13 Methods and compositions for treatment of cartilage damage and arthritis
KR1020197016715A KR20190084287A (ko) 2016-11-14 2017-11-13 연골 손상 및 관절염 치료 방법 및 조성물

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020197016715A Division KR20190084287A (ko) 2016-11-14 2017-11-13 연골 손상 및 관절염 치료 방법 및 조성물

Publications (1)

Publication Number Publication Date
KR20240045351A true KR20240045351A (ko) 2024-04-05

Family

ID=60629753

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020247009753A Pending KR20240045351A (ko) 2016-11-14 2017-11-13 연골 손상 및 관절염 치료 방법 및 조성물
KR1020197016715A Ceased KR20190084287A (ko) 2016-11-14 2017-11-13 연골 손상 및 관절염 치료 방법 및 조성물

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020197016715A Ceased KR20190084287A (ko) 2016-11-14 2017-11-13 연골 손상 및 관절염 치료 방법 및 조성물

Country Status (10)

Country Link
US (3) US11351223B2 (cg-RX-API-DMAC7.html)
EP (1) EP3538127A1 (cg-RX-API-DMAC7.html)
JP (2) JP2019535707A (cg-RX-API-DMAC7.html)
KR (2) KR20240045351A (cg-RX-API-DMAC7.html)
CN (2) CN109963579A (cg-RX-API-DMAC7.html)
AU (2) AU2017357785A1 (cg-RX-API-DMAC7.html)
CA (1) CA3043667A1 (cg-RX-API-DMAC7.html)
IL (1) IL266361B2 (cg-RX-API-DMAC7.html)
MX (2) MX2019005621A (cg-RX-API-DMAC7.html)
WO (1) WO2018087727A1 (cg-RX-API-DMAC7.html)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117355323A (zh) 2021-05-24 2024-01-05 诺华股份有限公司 用于治疗骨关节炎的方法
TW202306970A (zh) 2021-05-24 2023-02-16 瑞士商諾華公司 用於治療骨關節炎之方法
WO2023084388A1 (en) * 2021-11-10 2023-05-19 Novartis Ag Methods for determining the biological activity of angptl polypeptides

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2464532T3 (es) 2001-04-19 2014-06-03 The Scripps Research Institute Métodos y composiciones para la producción de pares ortogonales de ARNt-aminoacil-ARNt sintetasa
MXPA05003983A (es) 2002-10-16 2005-06-22 Scripps Research Inst Incorporacion en sitio especifico de cetoaminoacidos en proteinas.
EP1558747B1 (en) 2002-10-16 2009-10-14 The Scripps Research Institute Glycoprotein synthesis
JP5642916B2 (ja) 2003-04-17 2014-12-17 ザ スクリプス リサーチ インスティテュート 真核遺伝コードの拡張
WO2005019415A2 (en) 2003-07-07 2005-03-03 The Scripps Research Institute Compositions of orthogonal lysyl-trna and aminoacyl-trna synthetase pairs and uses thereof
EP1704242A4 (en) 2003-07-07 2008-06-18 Scripps Research Inst COMPOSITIONS WITH PAIRS OF ORTHOGONAL LEUCYL-TRNA AND AMINOACYL-TRNA-SYNTHETASE AND USES THEREOF
WO2005007624A2 (en) 2003-07-07 2005-01-27 The Scripps Research Institute Compositions of orthogonal glutamyl-trna and aminoacyl trna synthetase pairs and uses thereof
MX2007003142A (es) 2004-09-21 2007-07-04 Scripps Research Inst Incorporacion in vivo de alquinil aminoacidos a proteinas en eubacterias.
MX2007004892A (es) 2004-10-27 2007-08-16 Scripps Research Inst Componentes de traduccion ortogonales para la incorporacion in vivo de aminoacidos no naturales.
MX2008011470A (es) 2006-03-09 2008-09-24 Scripps Research Inst Sistemas para la expresion de componentes de traduccion ortogonales en celulas huesped eubacterianas.
EP2118150B1 (en) 2007-02-14 2015-09-23 Biocompatibles UK Limited Derivatisation of biological molecules
CA2746395C (en) * 2008-12-10 2019-07-09 Ablynx N.V. Polypeptides comprising amino acid sequences directed against tie 2 for the treatment of diseases and disorders related to angiogenesis
PE20160507A1 (es) * 2009-07-14 2016-05-20 Scripps Research Inst Diferenciacion de celulas madre mesenquimales
UY32979A (es) * 2009-10-28 2011-02-28 Abbott Lab Inmunoglobulinas con dominio variable dual y usos de las mismas
AU2013204754C1 (en) * 2012-05-16 2018-10-11 Takeda Pharmaceutical Company Limited Nucleophilic Catalysts for Oxime Linkage
US9301971B2 (en) * 2013-03-08 2016-04-05 Novartis Ag Peptides and compositions for treatment of joint damage
UY35368A (es) * 2013-03-08 2014-10-31 Irm Llc Péptidos y composiciones para el tratamiento de daño articular
EP2968330B1 (en) * 2013-03-15 2021-09-29 The Scripps Research Institute Compounds and methods for inducing chondrogenesis
HRP20241236T1 (hr) * 2014-05-13 2024-12-06 Novartis Ag Spojevi i pripravci za induciranje hondrogeneze

Also Published As

Publication number Publication date
MX2022011897A (es) 2022-10-18
CN117860868A (zh) 2024-04-12
AU2017357785A1 (en) 2019-04-11
AU2020281098A1 (en) 2021-01-14
JP2019535707A (ja) 2019-12-12
US20250302915A1 (en) 2025-10-02
RU2019117884A (ru) 2020-12-14
AU2020281098B2 (en) 2024-05-02
MX2019005621A (es) 2019-08-12
US20220331398A1 (en) 2022-10-20
RU2019117884A3 (cg-RX-API-DMAC7.html) 2021-02-05
CA3043667A1 (en) 2018-05-17
US11351223B2 (en) 2022-06-07
CN109963579A (zh) 2019-07-02
WO2018087727A1 (en) 2018-05-17
IL266361B1 (en) 2023-10-01
IL266361A (en) 2019-06-30
US20190269754A1 (en) 2019-09-05
KR20190084287A (ko) 2019-07-16
EP3538127A1 (en) 2019-09-18
JP2023039962A (ja) 2023-03-22
IL266361B2 (en) 2024-02-01
AU2017357785A2 (en) 2019-05-02

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