KR20240040776A - 소아 좌심 형성부전 증후군의 치료에 있어서의 중간엽 줄기 세포의 용도 - Google Patents

소아 좌심 형성부전 증후군의 치료에 있어서의 중간엽 줄기 세포의 용도 Download PDF

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Publication number
KR20240040776A
KR20240040776A KR1020247006241A KR20247006241A KR20240040776A KR 20240040776 A KR20240040776 A KR 20240040776A KR 1020247006241 A KR1020247006241 A KR 1020247006241A KR 20247006241 A KR20247006241 A KR 20247006241A KR 20240040776 A KR20240040776 A KR 20240040776A
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KR
South Korea
Prior art keywords
patient
stem cells
mesenchymal stem
change
administration
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Pending
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KR1020247006241A
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English (en)
Korean (ko)
Inventor
조슈아 엠. 헤어
선제이 코샬
Original Assignee
롱에버론 인코포레이티드
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Publication of KR20240040776A publication Critical patent/KR20240040776A/ko
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/026—Measuring blood flow
    • A61B5/029—Measuring blood output from the heart, e.g. minute volume
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Physiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020247006241A 2021-07-26 2022-07-26 소아 좌심 형성부전 증후군의 치료에 있어서의 중간엽 줄기 세포의 용도 Pending KR20240040776A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163203519P 2021-07-26 2021-07-26
US63/203,519 2021-07-26
PCT/US2022/038370 WO2023009537A1 (en) 2021-07-26 2022-07-26 Use of mesenchymal stem cells in treatment of juvenile hypoplastic left heart syndrome

Publications (1)

Publication Number Publication Date
KR20240040776A true KR20240040776A (ko) 2024-03-28

Family

ID=83049982

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020247006241A Pending KR20240040776A (ko) 2021-07-26 2022-07-26 소아 좌심 형성부전 증후군의 치료에 있어서의 중간엽 줄기 세포의 용도

Country Status (9)

Country Link
US (1) US20240350549A1 (https=)
EP (1) EP4376950A1 (https=)
JP (1) JP2024527034A (https=)
KR (1) KR20240040776A (https=)
CN (1) CN117999082A (https=)
AU (1) AU2022316959A1 (https=)
CA (1) CA3227475A1 (https=)
TW (1) TW202321437A (https=)
WO (1) WO2023009537A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025062365A1 (en) * 2023-09-22 2025-03-27 Mesoblast International Sárl Mesenchymal lineage precursor or stem cells (mlpscs) for use in methods of treating congenital heart disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20180105705A (ko) 2016-02-04 2018-09-28 롱에버론 엘엘씨 백신 보조제로서의 중간엽 줄기 세포 및 그의 사용 방법
JP7276664B2 (ja) 2016-11-11 2023-05-18 ロングエバーオン インコーポレイテッド 細胞性及び体液性免疫を達成するためのヒト間葉系幹細胞を使用する方法
SG11201912209UA (en) 2017-06-19 2020-01-30 Longeveron Llc Treatment of sexual dysfunction and improvement in sexual quality of life
AU2020356193A1 (en) * 2019-09-24 2022-05-19 Children's Hospital Of Philadelphia Methods of improving exercise performance, single ventricular performance, and myocardial performance index (MPI) in single ventricle heart disease, using udenafil compositions

Also Published As

Publication number Publication date
TW202321437A (zh) 2023-06-01
CN117999082A (zh) 2024-05-07
WO2023009537A1 (en) 2023-02-02
AU2022316959A1 (en) 2024-02-29
EP4376950A1 (en) 2024-06-05
CA3227475A1 (en) 2023-02-02
JP2024527034A (ja) 2024-07-19
US20240350549A1 (en) 2024-10-24

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Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20240223

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20250624

Comment text: Request for Examination of Application