CN117999082A - 间充质干细胞在治疗青少年左心发育不良综合征中的用途 - Google Patents

间充质干细胞在治疗青少年左心发育不良综合征中的用途 Download PDF

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Publication number
CN117999082A
CN117999082A CN202280062443.6A CN202280062443A CN117999082A CN 117999082 A CN117999082 A CN 117999082A CN 202280062443 A CN202280062443 A CN 202280062443A CN 117999082 A CN117999082 A CN 117999082A
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China
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patient
stem cells
mesenchymal stem
change
administration
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Pending
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CN202280062443.6A
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English (en)
Chinese (zh)
Inventor
约书亚·M·哈尔
S·考沙尔
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Meishang Life Sciences Co ltd
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Meishang Life Sciences Co ltd
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Publication of CN117999082A publication Critical patent/CN117999082A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/026—Measuring blood flow
    • A61B5/029—Measuring blood output from the heart, e.g. minute volume
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Physiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN202280062443.6A 2021-07-26 2022-07-26 间充质干细胞在治疗青少年左心发育不良综合征中的用途 Pending CN117999082A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163203519P 2021-07-26 2021-07-26
US63/203,519 2021-07-26
PCT/US2022/038370 WO2023009537A1 (en) 2021-07-26 2022-07-26 Use of mesenchymal stem cells in treatment of juvenile hypoplastic left heart syndrome

Publications (1)

Publication Number Publication Date
CN117999082A true CN117999082A (zh) 2024-05-07

Family

ID=83049982

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202280062443.6A Pending CN117999082A (zh) 2021-07-26 2022-07-26 间充质干细胞在治疗青少年左心发育不良综合征中的用途

Country Status (9)

Country Link
US (1) US20240350549A1 (https=)
EP (1) EP4376950A1 (https=)
JP (1) JP2024527034A (https=)
KR (1) KR20240040776A (https=)
CN (1) CN117999082A (https=)
AU (1) AU2022316959A1 (https=)
CA (1) CA3227475A1 (https=)
TW (1) TW202321437A (https=)
WO (1) WO2023009537A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025062365A1 (en) * 2023-09-22 2025-03-27 Mesoblast International Sárl Mesenchymal lineage precursor or stem cells (mlpscs) for use in methods of treating congenital heart disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20180105705A (ko) 2016-02-04 2018-09-28 롱에버론 엘엘씨 백신 보조제로서의 중간엽 줄기 세포 및 그의 사용 방법
JP7276664B2 (ja) 2016-11-11 2023-05-18 ロングエバーオン インコーポレイテッド 細胞性及び体液性免疫を達成するためのヒト間葉系幹細胞を使用する方法
SG11201912209UA (en) 2017-06-19 2020-01-30 Longeveron Llc Treatment of sexual dysfunction and improvement in sexual quality of life
AU2020356193A1 (en) * 2019-09-24 2022-05-19 Children's Hospital Of Philadelphia Methods of improving exercise performance, single ventricular performance, and myocardial performance index (MPI) in single ventricle heart disease, using udenafil compositions

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Publication number Publication date
TW202321437A (zh) 2023-06-01
KR20240040776A (ko) 2024-03-28
WO2023009537A1 (en) 2023-02-02
AU2022316959A1 (en) 2024-02-29
EP4376950A1 (en) 2024-06-05
CA3227475A1 (en) 2023-02-02
JP2024527034A (ja) 2024-07-19
US20240350549A1 (en) 2024-10-24

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