KR20240027583A

KR20240027583A - 폐암 치료를 위한 피리미디닐아미노벤젠

폐암 치료를 위한 피리미디닐아미노벤젠 Download PDF

Info

Publication number: KR20240027583A
Authority: KR; South Korea
Prior art keywords: amino; methyl; compound; ethyl; pyrimidin
Prior art date: 2021-04-30
Legal status : Pending

Application number

KR1020237040518A

Other languages

English (en)

Korean (ko)

Inventor

마오셍 두안

슈아이 유안

Original Assignee

수조우 푸허 바이오파마 컴퍼니 리미티드

Priority date

2021-04-30

Filing date

2022-05-02

Publication date

2024-03-04

2022-05-02 Application filed by 수조우 푸허 바이오파마 컴퍼니 리미티드 filed Critical 수조우 푸허 바이오파마 컴퍼니 리미티드

2024-03-04 Publication of KR20240027583A publication Critical patent/KR20240027583A/ko

Status Pending legal-status Critical Current

Links

208000020816 lung neoplasm Diseases 0.000 title claims abstract description 77
206010058467 Lung neoplasm malignant Diseases 0.000 title claims abstract description 76
201000005202 lung cancer Diseases 0.000 title claims abstract description 76
XGXNTJHZPBRBHJ-UHFFFAOYSA-N n-phenylpyrimidin-2-amine Chemical compound N=1C=CC=NC=1NC1=CC=CC=C1 XGXNTJHZPBRBHJ-UHFFFAOYSA-N 0.000 title abstract description 3
238000011282 treatment Methods 0.000 title description 17
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OEFWUILIMFIVSE-UHFFFAOYSA-N N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[4-(8-methylimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide Chemical compound C1=C(C=2N3C(=NC=2)C(=CC=C3)C)N=C(N=C1)NC1=C(C=C(C(=C1)NC(=O)C=C)N(CCN(C)C)C)OC OEFWUILIMFIVSE-UHFFFAOYSA-N 0.000 claims description 103
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HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 claims description 29
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