KR20240011714A - 치료용 항체를 발현하는 비바이러스성 dna 벡터 및 이의 용도 - Google Patents

치료용 항체를 발현하는 비바이러스성 dna 벡터 및 이의 용도 Download PDF

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KR20240011714A
KR20240011714A KR1020237040614A KR20237040614A KR20240011714A KR 20240011714 A KR20240011714 A KR 20240011714A KR 1020237040614 A KR1020237040614 A KR 1020237040614A KR 20237040614 A KR20237040614 A KR 20237040614A KR 20240011714 A KR20240011714 A KR 20240011714A
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cedna
cedna vector
itr
itrs
nucleic acid
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Korean (ko)
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나다니엘 실버
더글라스 앤서니 커
필립 사마요아
싯다르트 진달
라파엘 가네
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제너레이션 바이오 컴퍼니
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    • A—HUMAN NECESSITIES
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
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    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
    • A61K48/0016—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the nucleic acid is delivered as a 'naked' nucleic acid, i.e. not combined with an entity such as a cationic lipid
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
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    • C07K16/10—RNA viruses
    • C07K16/102—Coronaviridae (F)
    • C07K16/104—Severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2]
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    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
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    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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    • C12N2710/00011—Details
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    • C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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KR1020237040614A 2021-04-27 2022-04-27 치료용 항체를 발현하는 비바이러스성 dna 벡터 및 이의 용도 Pending KR20240011714A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163180382P 2021-04-27 2021-04-27
US63/180,382 2021-04-27
PCT/US2022/026560 WO2022232289A1 (en) 2021-04-27 2022-04-27 Non-viral dna vectors expressing therapeutic antibodies and uses thereof

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KR20240011714A true KR20240011714A (ko) 2024-01-26

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KR1020237040614A Pending KR20240011714A (ko) 2021-04-27 2022-04-27 치료용 항체를 발현하는 비바이러스성 dna 벡터 및 이의 용도

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US (1) US20240226324A1 (https=)
EP (1) EP4329885A1 (https=)
JP (1) JP2024515788A (https=)
KR (1) KR20240011714A (https=)
CN (1) CN117881786A (https=)
AU (1) AU2022264509A1 (https=)
CA (1) CA3216585A1 (https=)
IL (1) IL308404A (https=)
MX (1) MX2023012643A (https=)
WO (1) WO2022232289A1 (https=)

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