KR20230155616A - 전기천공을 사용하여 지방 조직의 생체내 형질감염을 최소로 침습성으로 하기 위한 방법 및 장치 - Google Patents

전기천공을 사용하여 지방 조직의 생체내 형질감염을 최소로 침습성으로 하기 위한 방법 및 장치 Download PDF

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Publication number
KR20230155616A
KR20230155616A KR1020237037846A KR20237037846A KR20230155616A KR 20230155616 A KR20230155616 A KR 20230155616A KR 1020237037846 A KR1020237037846 A KR 1020237037846A KR 20237037846 A KR20237037846 A KR 20237037846A KR 20230155616 A KR20230155616 A KR 20230155616A
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South Korea
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tissue
electrode
contact surface
layer
applying
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Pending
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KR1020237037846A
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English (en)
Korean (ko)
Inventor
폴 피셔
케이트 브로데릭
제이 맥코이
Original Assignee
이노비오 파마수티컬즈, 인크.
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Publication of KR20230155616A publication Critical patent/KR20230155616A/ko
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • A61N1/0416—Anode and cathode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • A61N1/0416—Anode and cathode
    • A61N1/042—Material of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • A61N1/0416—Anode and cathode
    • A61N1/0424—Shape of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Surgical Instruments (AREA)
  • Electrotherapy Devices (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Prostheses (AREA)
KR1020237037846A 2016-09-23 2017-09-22 전기천공을 사용하여 지방 조직의 생체내 형질감염을 최소로 침습성으로 하기 위한 방법 및 장치 Pending KR20230155616A (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201662398932P 2016-09-23 2016-09-23
US62/398,932 2016-09-23
US201762480180P 2017-03-31 2017-03-31
US62/480,180 2017-03-31
KR1020227024752A KR102599298B1 (ko) 2016-09-23 2017-09-22 전기천공을 사용하여 지방 조직의 생체내 형질감염을 최소로 침습성으로 하기 위한 방법 및 장치
PCT/US2017/052970 WO2018057900A1 (en) 2016-09-23 2017-09-22 Method and device for minimally invasive in vivo transfection of adipose tissue using electroporation

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020227024752A Division KR102599298B1 (ko) 2016-09-23 2017-09-22 전기천공을 사용하여 지방 조직의 생체내 형질감염을 최소로 침습성으로 하기 위한 방법 및 장치

Publications (1)

Publication Number Publication Date
KR20230155616A true KR20230155616A (ko) 2023-11-10

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Family Applications (4)

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KR1020237037846A Pending KR20230155616A (ko) 2016-09-23 2017-09-22 전기천공을 사용하여 지방 조직의 생체내 형질감염을 최소로 침습성으로 하기 위한 방법 및 장치
KR1020197010846A Active KR102313881B1 (ko) 2016-09-23 2017-09-22 전기천공을 사용하여 지방 조직의 생체내 형질감염을 최소로 침습성으로 하기 위한 방법 및 장치
KR1020227024752A Active KR102599298B1 (ko) 2016-09-23 2017-09-22 전기천공을 사용하여 지방 조직의 생체내 형질감염을 최소로 침습성으로 하기 위한 방법 및 장치
KR1020217032742A Active KR102423446B1 (ko) 2016-09-23 2017-09-22 전기천공을 사용하여 지방 조직의 생체내 형질감염을 최소로 침습성으로 하기 위한 방법 및 장치

Family Applications After (3)

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KR1020197010846A Active KR102313881B1 (ko) 2016-09-23 2017-09-22 전기천공을 사용하여 지방 조직의 생체내 형질감염을 최소로 침습성으로 하기 위한 방법 및 장치
KR1020227024752A Active KR102599298B1 (ko) 2016-09-23 2017-09-22 전기천공을 사용하여 지방 조직의 생체내 형질감염을 최소로 침습성으로 하기 위한 방법 및 장치
KR1020217032742A Active KR102423446B1 (ko) 2016-09-23 2017-09-22 전기천공을 사용하여 지방 조직의 생체내 형질감염을 최소로 침습성으로 하기 위한 방법 및 장치

Country Status (10)

Country Link
US (2) US11684777B2 (https=)
EP (2) EP3515549B1 (https=)
JP (3) JP7181186B2 (https=)
KR (4) KR20230155616A (https=)
CN (2) CN117482374A (https=)
AU (4) AU2017331263B2 (https=)
CA (2) CA3037527A1 (https=)
ES (1) ES2970888T3 (https=)
MX (2) MX2019003335A (https=)
WO (1) WO2018057900A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3615660A4 (en) * 2017-04-26 2021-01-13 Ravata Solutions, Inc. MICROELECTRODE PROCESSING FOR ELECTROPORATION
AU2021388154A1 (en) * 2020-11-25 2023-06-22 Flagship Pioneering Innovations Vi, Llc Adipogenic cell compositions and methods

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US6216034B1 (en) * 1997-08-01 2001-04-10 Genetronics, Inc. Method of programming an array of needle electrodes for electroporation therapy of tissue
US6778853B1 (en) * 1997-12-17 2004-08-17 University Of South Florida Electroporation device
JP2000139943A (ja) 1998-09-02 2000-05-23 Olympus Optical Co Ltd 高周波処置具
JP3384750B2 (ja) 1998-09-02 2003-03-10 オリンパス光学工業株式会社 高周波処置具
US6937890B2 (en) 1998-12-17 2005-08-30 University Of South Florida Nonpenetrating electroporation device
DE10032000A1 (de) 1999-07-01 2001-01-25 Medtronic Inc Medizinisches Gerät und Verfahren zur elektrophoretischen in situ Abgabe eines therapheutischen Wirkstoffs
US8251986B2 (en) * 2000-08-17 2012-08-28 Angiodynamics, Inc. Method of destroying tissue cells by eletroporation
US6892099B2 (en) * 2001-02-08 2005-05-10 Minnesota Medical Physics, Llc Apparatus and method for reducing subcutaneous fat deposits, virtual face lift and body sculpturing by electroporation
US6697670B2 (en) 2001-08-17 2004-02-24 Minnesota Medical Physics, Llc Apparatus and method for reducing subcutaneous fat deposits by electroporation with improved comfort of patients
US20040204669A1 (en) * 2001-07-05 2004-10-14 Hofmann Gunter A. Apparatus for electroporation mediated delivery for drugs and genes
JP3895633B2 (ja) 2002-04-19 2007-03-22 株式会社ザナヴィ・インフォマティクス 表示装置、情報処理装置、情報処理システム
JP2006293725A (ja) 2005-04-12 2006-10-26 Matsushita Electric Ind Co Ltd Ｌｓｉシステム向けデバッグ装置
US20060293725A1 (en) 2005-06-24 2006-12-28 Boris Rubinsky Methods and systems for treating fatty tissue sites using electroporation
EP1928540A4 (en) 2005-09-07 2010-03-10 The Foundry Inc DEVICE AND METHOD FOR INTERRUPTING SUBCUTANEOUS STRUCTURES
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JP5098024B2 (ja) 2007-11-07 2012-12-12 有限会社リバー精工 内視鏡用高周波処置具
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Publication number Publication date
KR102423446B1 (ko) 2022-07-21
EP4238607A3 (en) 2023-11-08
ES2970888T3 (es) 2024-05-31
BR112019005740A2 (pt) 2019-06-18
AU2023202108A1 (en) 2023-05-04
US11684777B2 (en) 2023-06-27
CN110022931B (zh) 2023-11-14
JP7181186B2 (ja) 2022-11-30
CN117482374A (zh) 2024-02-02
WO2018057900A1 (en) 2018-03-29
US20200016400A1 (en) 2020-01-16
KR102313881B1 (ko) 2021-10-18
JP7448603B2 (ja) 2024-03-12
US20230248965A1 (en) 2023-08-10
CN110022931A (zh) 2019-07-16
EP3515549A1 (en) 2019-07-31
CA3204936A1 (en) 2018-03-29
MX2024007241A (es) 2024-06-26
KR102599298B1 (ko) 2023-11-07
AU2017331263B2 (en) 2020-07-09
MX2019003335A (es) 2019-12-11
EP3515549A4 (en) 2020-06-10
JP2020500039A (ja) 2020-01-09
JP2022188120A (ja) 2022-12-20
KR20190055155A (ko) 2019-05-22
JP2024054418A (ja) 2024-04-16
KR20210127797A (ko) 2021-10-22
AU2020250317A1 (en) 2020-11-12
AU2017331263A1 (en) 2019-04-18
KR20220104077A (ko) 2022-07-25
AU2020250317B2 (en) 2023-01-05
AU2025213675A1 (en) 2025-08-28
CA3037527A1 (en) 2018-03-29
EP4238607A2 (en) 2023-09-06
EP3515549B1 (en) 2023-11-22

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