KR20230133285A - 약제학적 제형 - Google Patents

약제학적 제형 Download PDF

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Publication number
KR20230133285A
KR20230133285A KR1020237023066A KR20237023066A KR20230133285A KR 20230133285 A KR20230133285 A KR 20230133285A KR 1020237023066 A KR1020237023066 A KR 1020237023066A KR 20237023066 A KR20237023066 A KR 20237023066A KR 20230133285 A KR20230133285 A KR 20230133285A
Authority
KR
South Korea
Prior art keywords
semi
compound
pharmaceutical formulation
solid
amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
KR1020237023066A
Other languages
English (en)
Korean (ko)
Inventor
리처드 아머
마르셀 데 마타스
Original Assignee
레드엑스 파마 피엘씨
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 레드엑스 파마 피엘씨 filed Critical 레드엑스 파마 피엘씨
Publication of KR20230133285A publication Critical patent/KR20230133285A/ko
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • A61K31/497Non-condensed pyrazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material
    • A61K9/4825Proteins, e.g. gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833Encapsulating processes; Filling of capsules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020237023066A 2021-01-15 2022-01-14 약제학적 제형 Pending KR20230133285A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB2100526.9A GB202100526D0 (en) 2021-01-15 2021-01-15 Pharmaceutical formulation
GB2100526.9 2021-01-15
PCT/GB2022/050083 WO2022153062A1 (en) 2021-01-15 2022-01-14 Pharmaceutical formulation

Publications (1)

Publication Number Publication Date
KR20230133285A true KR20230133285A (ko) 2023-09-19

Family

ID=74678956

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020237023066A Pending KR20230133285A (ko) 2021-01-15 2022-01-14 약제학적 제형

Country Status (10)

Country Link
US (1) US20240082244A1 (https=)
EP (1) EP4277606A1 (https=)
JP (1) JP2024505630A (https=)
KR (1) KR20230133285A (https=)
CN (1) CN116710077A (https=)
AU (1) AU2022208241A1 (https=)
CA (1) CA3202029A1 (https=)
GB (1) GB202100526D0 (https=)
MX (1) MX2023008406A (https=)
WO (1) WO2022153062A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220023266A1 (en) 2018-12-07 2022-01-27 Neurocrine Biosciences, Inc. Crf1 receptor antagonist, pharmaceutical formulations and solid forms thereof for the treatment of congenital adrenal hyperplasia
JP7623365B2 (ja) 2019-09-27 2025-01-28 ニューロクライン バイオサイエンシーズ,インコーポレイテッド Crf受容体アンタゴニストおよび使用方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA845180B (en) * 1983-07-07 1986-02-26 American Home Prod Pharmaceutical composition containing a liquid lubricant
US9783550B2 (en) * 2013-05-14 2017-10-10 The Board Of Regents Of The University Of Texas System Highly potent inhibitors of porcupine
KR102525131B1 (ko) * 2014-10-08 2023-04-24 레드엑스 파마 피엘씨 Wnt 신호 경로의 억제제로서의 N-피리디닐 아세트아미드 유도체
CN111971063A (zh) * 2018-04-06 2020-11-20 4阵营疗法公司 通过靶向调节基因信号传导网络治疗疾病

Also Published As

Publication number Publication date
AU2022208241A9 (en) 2025-01-09
JP2024505630A (ja) 2024-02-07
GB202100526D0 (en) 2021-03-03
MX2023008406A (es) 2023-08-03
EP4277606A1 (en) 2023-11-22
AU2022208241A1 (en) 2023-07-06
US20240082244A1 (en) 2024-03-14
CN116710077A (zh) 2023-09-05
CA3202029A1 (en) 2022-07-21
WO2022153062A1 (en) 2022-07-21

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Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20230706

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20241118

Comment text: Request for Examination of Application