KR20230124616A - 지질 펩티드의 제조방법 - Google Patents

지질 펩티드의 제조방법 Download PDF

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Publication number
KR20230124616A
KR20230124616A KR1020237023450A KR20237023450A KR20230124616A KR 20230124616 A KR20230124616 A KR 20230124616A KR 1020237023450 A KR1020237023450 A KR 1020237023450A KR 20237023450 A KR20237023450 A KR 20237023450A KR 20230124616 A KR20230124616 A KR 20230124616A
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KR
South Korea
Prior art keywords
group
formula
carbon atoms
compound represented
gly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
KR1020237023450A
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English (en)
Korean (ko)
Inventor
타케아키 쇼지
Original Assignee
닛산 가가쿠 가부시키가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 닛산 가가쿠 가부시키가이샤 filed Critical 닛산 가가쿠 가부시키가이샤
Publication of KR20230124616A publication Critical patent/KR20230124616A/ko
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06043—Leu-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06052—Val-amino acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1020237023450A 2020-12-25 2021-12-24 지질 펩티드의 제조방법 Pending KR20230124616A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020217730 2020-12-25
JPJP-P-2020-217730 2020-12-25
PCT/JP2021/048365 WO2022138953A1 (ja) 2020-12-25 2021-12-24 脂質ペプチドの製造方法

Publications (1)

Publication Number Publication Date
KR20230124616A true KR20230124616A (ko) 2023-08-25

Family

ID=82158264

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020237023450A Pending KR20230124616A (ko) 2020-12-25 2021-12-24 지질 펩티드의 제조방법

Country Status (7)

Country Link
US (1) US20240067675A1 (https=)
EP (1) EP4265629A4 (https=)
JP (1) JP7787501B2 (https=)
KR (1) KR20230124616A (https=)
CN (1) CN116648455A (https=)
TW (1) TW202241920A (https=)
WO (1) WO2022138953A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202241919A (zh) * 2020-12-25 2022-11-01 日商日產化學股份有限公司 脂質胜肽之製造方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010013555A1 (ja) 2008-08-01 2010-02-04 日産化学工業株式会社 新規脂質ジペプチド並びにゲル
WO2011027897A1 (ja) 2009-09-07 2011-03-10 日産化学工業株式会社 脂質ペプチド化合物の製造方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1184770C2 (de) * 1961-06-01 1965-09-02 Hoffmann La Roche Verfahren zur Herstellung von antibacteriell wirksamen Peptiden
JP5183907B2 (ja) 2006-11-07 2013-04-17 株式会社パーマケム・アジア ペリンドプリルの前駆体の製造方法、及び、ペリンドプリルエルブミンの製造方法と精製方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010013555A1 (ja) 2008-08-01 2010-02-04 日産化学工業株式会社 新規脂質ジペプチド並びにゲル
WO2011027897A1 (ja) 2009-09-07 2011-03-10 日産化学工業株式会社 脂質ペプチド化合物の製造方法

Also Published As

Publication number Publication date
TW202241920A (zh) 2022-11-01
CN116648455A (zh) 2023-08-25
JP7787501B2 (ja) 2025-12-17
EP4265629A1 (en) 2023-10-25
JPWO2022138953A1 (https=) 2022-06-30
US20240067675A1 (en) 2024-02-29
EP4265629A4 (en) 2024-11-27
WO2022138953A1 (ja) 2022-06-30

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PA0105 International application

Patent event date: 20230711

Patent event code: PA01051R01D

Comment text: International Patent Application

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A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20241127

Comment text: Request for Examination of Application