JP7787501B2 - 脂質ペプチドの製造方法 - Google Patents

脂質ペプチドの製造方法

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Publication number
JP7787501B2
JP7787501B2 JP2022571707A JP2022571707A JP7787501B2 JP 7787501 B2 JP7787501 B2 JP 7787501B2 JP 2022571707 A JP2022571707 A JP 2022571707A JP 2022571707 A JP2022571707 A JP 2022571707A JP 7787501 B2 JP7787501 B2 JP 7787501B2
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JP
Japan
Prior art keywords
group
formula
carbon atoms
gly
compound represented
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2022571707A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2022138953A1 (https=
Inventor
武明 庄子
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nissan Chemical Corp
Original Assignee
Nissan Chemical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Corp filed Critical Nissan Chemical Corp
Publication of JPWO2022138953A1 publication Critical patent/JPWO2022138953A1/ja
Application granted granted Critical
Publication of JP7787501B2 publication Critical patent/JP7787501B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06043—Leu-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06052—Val-amino acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2022571707A 2020-12-25 2021-12-24 脂質ペプチドの製造方法 Active JP7787501B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020217730 2020-12-25
JP2020217730 2020-12-25
PCT/JP2021/048365 WO2022138953A1 (ja) 2020-12-25 2021-12-24 脂質ペプチドの製造方法

Publications (2)

Publication Number Publication Date
JPWO2022138953A1 JPWO2022138953A1 (https=) 2022-06-30
JP7787501B2 true JP7787501B2 (ja) 2025-12-17

Family

ID=82158264

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022571707A Active JP7787501B2 (ja) 2020-12-25 2021-12-24 脂質ペプチドの製造方法

Country Status (7)

Country Link
US (1) US20240067675A1 (https=)
EP (1) EP4265629A4 (https=)
JP (1) JP7787501B2 (https=)
KR (1) KR20230124616A (https=)
CN (1) CN116648455A (https=)
TW (1) TW202241920A (https=)
WO (1) WO2022138953A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202241919A (zh) * 2020-12-25 2022-11-01 日商日產化學股份有限公司 脂質胜肽之製造方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3265682A (en) 1961-06-01 1966-08-09 Hoffmann La Roche Peptide compounds
JP2008115127A (ja) 2006-11-07 2008-05-22 Permachem Asia Ltd ペリンドプリルの前駆体の製造方法、及びペリンドプリルの前駆体、並びにペリンドプリルエルブミンの製造方法と精製方法
WO2011027897A1 (ja) 2009-09-07 2011-03-10 日産化学工業株式会社 脂質ペプチド化合物の製造方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5500071B2 (ja) 2008-08-01 2014-05-21 日産化学工業株式会社 新規脂質ジペプチド並びにゲル

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3265682A (en) 1961-06-01 1966-08-09 Hoffmann La Roche Peptide compounds
JP2008115127A (ja) 2006-11-07 2008-05-22 Permachem Asia Ltd ペリンドプリルの前駆体の製造方法、及びペリンドプリルの前駆体、並びにペリンドプリルエルブミンの製造方法と精製方法
WO2011027897A1 (ja) 2009-09-07 2011-03-10 日産化学工業株式会社 脂質ペプチド化合物の製造方法

Also Published As

Publication number Publication date
TW202241920A (zh) 2022-11-01
CN116648455A (zh) 2023-08-25
KR20230124616A (ko) 2023-08-25
EP4265629A1 (en) 2023-10-25
JPWO2022138953A1 (https=) 2022-06-30
US20240067675A1 (en) 2024-02-29
EP4265629A4 (en) 2024-11-27
WO2022138953A1 (ja) 2022-06-30

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