KR20230084163A - 항체-약물 접합체와 parp1 선택적 억제제의 조합 - Google Patents

항체-약물 접합체와 parp1 선택적 억제제의 조합 Download PDF

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KR20230084163A
KR20230084163A KR1020237011575A KR20237011575A KR20230084163A KR 20230084163 A KR20230084163 A KR 20230084163A KR 1020237011575 A KR1020237011575 A KR 1020237011575A KR 20237011575 A KR20237011575 A KR 20237011575A KR 20230084163 A KR20230084163 A KR 20230084163A
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cancer
pharmaceutical product
methyl
antibody
mmol
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Korean (ko)
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2세 제롬 토마스 메테탈
아자데 체라그치 바쉬 아스타네
엘리사베타 레오
얀 발레
Original Assignee
아스트라제네카 유케이 리미티드
다이이찌 산쿄 가부시키가이샤
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Publication of KR20230084163A publication Critical patent/KR20230084163A/ko
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

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KR1020237011575A 2020-10-09 2021-10-08 항체-약물 접합체와 parp1 선택적 억제제의 조합 Pending KR20230084163A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063089859P 2020-10-09 2020-10-09
US63/089,859 2020-10-09
PCT/IB2021/059232 WO2022074617A1 (en) 2020-10-09 2021-10-08 Combination of antibody-drug conjugate and parp1 selective inhibitor

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KR20230084163A true KR20230084163A (ko) 2023-06-12

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KR1020237011575A Pending KR20230084163A (ko) 2020-10-09 2021-10-08 항체-약물 접합체와 parp1 선택적 억제제의 조합

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US (1) US20230372527A1 (https=)
EP (1) EP4225314A1 (https=)
JP (1) JP2023545096A (https=)
KR (1) KR20230084163A (https=)
CN (1) CN116348115A (https=)
AU (1) AU2021356762A1 (https=)
BR (1) BR112023006337A2 (https=)
CA (1) CA3195117A1 (https=)
IL (1) IL301921A (https=)
MX (1) MX2023004047A (https=)
TW (1) TW202222350A (https=)
WO (1) WO2022074617A1 (https=)
ZA (1) ZA202305073B (https=)

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US11591331B2 (en) * 2021-04-19 2023-02-28 Xinthera, Inc. PARP1 inhibitors and uses thereof
CN115702156A (zh) * 2021-04-23 2023-02-14 南京明德新药研发有限公司 吡啶酰胺类化合物
WO2023051716A1 (zh) * 2021-09-30 2023-04-06 海思科医药集团股份有限公司 杂芳基衍生物parp抑制剂及其用途
AU2022392822A1 (en) * 2021-11-18 2024-05-02 Astrazeneca Uk Limited Combination of antibody-drug conjugate and parp1 selective inhibitor
AU2023235233A1 (en) 2022-03-14 2024-09-12 Slap Pharmaceuticals Llc Multicyclic compounds
EP4534537A4 (en) * 2022-05-25 2025-12-10 Xizang Haisco Pharmaceutical Co Ltd BICYCLE-DERIVED PARP INHIBITOR AND ITS USE
WO2024067694A1 (zh) * 2022-09-30 2024-04-04 中国医药研究开发中心有限公司 含氮杂环类化合物及其医药用途
CN120936382A (zh) * 2023-02-16 2025-11-11 阿斯利康(瑞典)有限公司 采用治疗性结合分子治疗癌症的组合疗法
TW202535479A (zh) 2023-12-05 2025-09-16 英商阿斯特捷利康英國股份有限公司 抗體藥物結合物與血腦屏障穿透性ｐａｒｐ１選擇性抑制劑之組合

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