KR20230057395A - 이중 가닥 파손의 단리 방법 - Google Patents

이중 가닥 파손의 단리 방법 Download PDF

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Publication number
KR20230057395A
KR20230057395A KR1020237009611A KR20237009611A KR20230057395A KR 20230057395 A KR20230057395 A KR 20230057395A KR 1020237009611 A KR1020237009611 A KR 1020237009611A KR 20237009611 A KR20237009611 A KR 20237009611A KR 20230057395 A KR20230057395 A KR 20230057395A
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oligonucleotide
sequence
adapter
binding
pair
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Korean (ko)
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사이먼 리드
펠릭스 돕스
에이크 패트릭 반
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유니버시티 칼리지 카디프 컨설턴츠 리미티드
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=72660690&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR20230057395(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 유니버시티 칼리지 카디프 컨설턴츠 리미티드 filed Critical 유니버시티 칼리지 카디프 컨설턴츠 리미티드
Publication of KR20230057395A publication Critical patent/KR20230057395A/ko
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    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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    • C12Q2521/00—Reaction characterised by the enzymatic activity
    • C12Q2521/30—Phosphoric diester hydrolysing, i.e. nuclease
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    • C12Q2521/00—Reaction characterised by the enzymatic activity
    • C12Q2521/30—Phosphoric diester hydrolysing, i.e. nuclease
    • C12Q2521/307—Single strand endonuclease
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    • C12Q2521/00—Reaction characterised by the enzymatic activity
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    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/155—Modifications characterised by incorporating/generating a new priming site
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    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/186—Modifications characterised by incorporating a non-extendable or blocking moiety
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    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/191—Modifications characterised by incorporating an adaptor
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    • C12Q2535/00—Reactions characterised by the assay type for determining the identity of a nucleotide base or a sequence of oligonucleotides
    • C12Q2535/122—Massive parallel sequencing
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
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  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
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  • Microbiology (AREA)
  • Biophysics (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
KR1020237009611A 2020-08-21 2021-08-20 이중 가닥 파손의 단리 방법 Pending KR20230057395A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB2013141.3 2020-08-21
GBGB2013141.3A GB202013141D0 (en) 2020-08-21 2020-08-21 A screening method for the detection of DNA damage
PCT/EP2021/073203 WO2022038291A1 (en) 2020-08-21 2021-08-20 A method for the isolation of double-strand breaks

Publications (1)

Publication Number Publication Date
KR20230057395A true KR20230057395A (ko) 2023-04-28

Family

ID=72660690

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KR1020237009611A Pending KR20230057395A (ko) 2020-08-21 2021-08-20 이중 가닥 파손의 단리 방법

Country Status (13)

Country Link
US (3) US20240011095A1 (https=)
EP (2) EP4368725B1 (https=)
JP (1) JP2023539169A (https=)
KR (1) KR20230057395A (https=)
CN (1) CN116472356A (https=)
AU (1) AU2021328724A1 (https=)
CA (1) CA3188635A1 (https=)
DK (1) DK4200443T3 (https=)
ES (1) ES2984253T3 (https=)
FI (1) FI4200443T3 (https=)
GB (1) GB202013141D0 (https=)
IL (1) IL300674A (https=)
WO (1) WO2022038291A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202013141D0 (en) 2020-08-21 2020-10-07 Univ College Cardiff Consultants Ltd A screening method for the detection of DNA damage
GB202209189D0 (en) 2022-06-22 2022-08-10 Broken String Biosciences Ltd Methods and compositions for nucleic acid sequencing
EP4569135A1 (en) 2022-08-09 2025-06-18 Institute of Molecular Biology gGmbH (IMB) Method of parallel, rapid and sensitive detection of dna double strand breaks
EP4321630A1 (en) * 2022-08-09 2024-02-14 Institute of Molecular Biology gGmbH (IMB) Method of parallel, rapid and sensitive detection of dna double strand breaks
GB202319988D0 (en) 2023-12-22 2024-02-07 Broken String Biosciences Ltd Methods of detecting dsbs and mutations

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EP3722409A1 (en) 2006-03-31 2020-10-14 Illumina, Inc. Systems and devices for sequence by synthesis analysis
CN104195227B (zh) 2008-11-07 2017-04-12 适应生物技术公司 通过序列分析监测状况的方法
WO2011086118A1 (en) 2010-01-14 2011-07-21 Deutsches Krebsforschungszentrum In vivo determination of the lokalization of dna double-stand breaks and application thereof
US8951781B2 (en) 2011-01-10 2015-02-10 Illumina, Inc. Systems, methods, and apparatuses to image a sample for biological or chemical analysis
WO2013006745A2 (en) 2011-07-07 2013-01-10 Immune Disease Institute, Inc. High throughput genome-wide translocation sequencing
RU2694686C2 (ru) 2013-03-12 2019-07-16 Е.И.Дюпон Де Немур Энд Компани Способы идентификации вариантных сайтов распознавания для редкощепящих сконструированных средств для индукции двунитевого разрыва, и композиции с ними, и их применения
DK2969479T3 (da) 2013-03-13 2021-08-02 Illumina Inc Væskeanordninger i flere lag og fremgangsmåder til deres fremstilling
US10208338B2 (en) * 2014-03-03 2019-02-19 Swift Biosciences, Inc. Enhanced adaptor ligation
EP3919621A1 (en) * 2014-06-23 2021-12-08 The General Hospital Corporation Genomewide unbiased identification of dsbs evaluated by sequencing (guide-seq)
WO2016081798A1 (en) 2014-11-20 2016-05-26 Children's Medical Center Corporation Methods relating to the detection of recurrent and non-specific double strand breaks in the genome
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WO2016138080A1 (en) 2015-02-24 2016-09-01 Trustees Of Boston University Protection of barcodes during dna amplification using molecular hairpins
JP2018530536A (ja) * 2015-09-11 2018-10-18 ザ ジェネラル ホスピタル コーポレイション ヌクレアーゼＤＳＢの完全照合およびシーケンシング（ＦＩＮＤ−ｓｅｑ）
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GB202013141D0 (en) 2020-08-21 2020-10-07 Univ College Cardiff Consultants Ltd A screening method for the detection of DNA damage

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Publication number Publication date
EP4368725A2 (en) 2024-05-15
EP4200443B1 (en) 2024-04-10
FI4200443T3 (fi) 2024-07-11
CN116472356A (zh) 2023-07-21
EP4368725A3 (en) 2024-05-29
IL300674A (en) 2023-04-01
AU2021328724A9 (en) 2023-04-27
EP4200443A1 (en) 2023-06-28
US20240309454A1 (en) 2024-09-19
US20240309455A1 (en) 2024-09-19
JP2023539169A (ja) 2023-09-13
US20240011095A1 (en) 2024-01-11
ES2984253T3 (es) 2024-10-29
WO2022038291A1 (en) 2022-02-24
CA3188635A1 (en) 2022-02-24
DK4200443T3 (da) 2024-07-22
EP4368725B1 (en) 2026-03-04
AU2021328724A1 (en) 2023-03-30
US12428683B2 (en) 2025-09-30
US12421554B2 (en) 2025-09-23
GB202013141D0 (en) 2020-10-07

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