KR20230042090A - 항-cd22 단일 도메인 항체 및 치료학적 작제물 - Google Patents

항-cd22 단일 도메인 항체 및 치료학적 작제물 Download PDF

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KR20230042090A
KR20230042090A KR1020237006141A KR20237006141A KR20230042090A KR 20230042090 A KR20230042090 A KR 20230042090A KR 1020237006141 A KR1020237006141 A KR 1020237006141A KR 20237006141 A KR20237006141 A KR 20237006141A KR 20230042090 A KR20230042090 A KR 20230042090A
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seq
amino acid
acid sequence
set forth
cdr2
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스콧 맥콤
리시니 위라트나
메디 아르바비-가라우디
티나 응우옌
쿤레 우
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내션얼 리서치 카운슬 오브 캐나다
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
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    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
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    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
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    • A61K40/421—Immunoglobulin superfamily
    • A61K40/4212—CD22, BL-CAM, siglec-2 or sialic acid binding Ig-related lectin 2
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    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • A—HUMAN NECESSITIES
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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KR1020237006141A 2020-07-29 2021-07-27 항-cd22 단일 도메인 항체 및 치료학적 작제물 Pending KR20230042090A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063058203P 2020-07-29 2020-07-29
US63/058,203 2020-07-29
PCT/CA2021/051046 WO2022020945A1 (en) 2020-07-29 2021-07-27 Anti-cd22 single domain antibodies and therapeutic constructs

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KR20230042090A true KR20230042090A (ko) 2023-03-27

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KR1020237006141A Pending KR20230042090A (ko) 2020-07-29 2021-07-27 항-cd22 단일 도메인 항체 및 치료학적 작제물

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US (1) US12703744B2 (enExample)
EP (1) EP4188952A4 (enExample)
JP (1) JP7869193B2 (enExample)
KR (1) KR20230042090A (enExample)
CN (1) CN116234559A (enExample)
AU (1) AU2021317073A1 (enExample)
BR (1) BR112023001452A2 (enExample)
CA (1) CA3187472A1 (enExample)
IL (1) IL300116A (enExample)
WO (1) WO2022020945A1 (enExample)

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WO2023154533A2 (en) * 2022-02-14 2023-08-17 Twist Bioscience Corporation Combinatorial dna assembly for multispecific antibodies

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Publication number Priority date Publication date Assignee Title
CN104822705B (zh) 2012-10-24 2019-07-12 美国卫生和人力服务部 M971嵌合抗原受体
CN105384825B (zh) 2015-08-11 2018-06-01 南京传奇生物科技有限公司 一种基于单域抗体的双特异性嵌合抗原受体及其应用
JP7377802B2 (ja) * 2017-12-20 2023-11-10 レンティジェン・テクノロジー・インコーポレイテッド 免疫療法を用いてｈｉｖ／ａｉｄｓを処置するための組成物および方法
WO2020053634A1 (en) * 2018-09-16 2020-03-19 Habibi Anbouhi Mahdi Anti-cd22 heavy-chain variable domain antibody
CN109970858B (zh) 2019-04-12 2023-05-09 深圳普瑞金生物药业股份有限公司 Cd22单域抗体、核苷酸序列及试剂盒
CN111217908B (zh) 2019-11-29 2021-07-06 深圳普瑞金生物药业有限公司 Cd22单域抗体、核苷酸序列、试剂盒、car-t病毒载体及car-t细胞

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AU2021317073A1 (en) 2023-02-16
CN116234559A (zh) 2023-06-06
EP4188952A1 (en) 2023-06-07
JP7869193B2 (ja) 2026-06-02
CA3187472A1 (en) 2022-02-03
US12703744B2 (en) 2026-08-11
BR112023001452A2 (pt) 2023-02-14
IL300116A (en) 2023-03-01
JP2023535485A (ja) 2023-08-17
US20230265185A1 (en) 2023-08-24
EP4188952A4 (en) 2025-03-19

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