KR20230017799A - 세포 및 유전자 요법을 위한 안정한 바이러스 벡터 생산자 세포를 생산하기 위한 조성물 및 방법 - Google Patents

세포 및 유전자 요법을 위한 안정한 바이러스 벡터 생산자 세포를 생산하기 위한 조성물 및 방법 Download PDF

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KR20230017799A
KR20230017799A KR1020227043618A KR20227043618A KR20230017799A KR 20230017799 A KR20230017799 A KR 20230017799A KR 1020227043618 A KR1020227043618 A KR 1020227043618A KR 20227043618 A KR20227043618 A KR 20227043618A KR 20230017799 A KR20230017799 A KR 20230017799A
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viral
viral vector
cell line
proteins
vector
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마이클 그린
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아이벡스솔, 아이엔씨.
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N2740/16041—Use of virus, viral particle or viral elements as a vector
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    • C12N2740/00—Reverse transcribing RNA viruses
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    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16051—Methods of production or purification of viral material
    • C12N2740/16052—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
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    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14151—Methods of production or purification of viral material
    • C12N2750/14152—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

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  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020227043618A 2020-05-15 2021-05-14 세포 및 유전자 요법을 위한 안정한 바이러스 벡터 생산자 세포를 생산하기 위한 조성물 및 방법 Pending KR20230017799A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063025812P 2020-05-15 2020-05-15
US63/025,812 2020-05-15
PCT/US2021/032479 WO2021231884A1 (en) 2020-05-15 2021-05-14 Compositions and methods for producing stable viral vector producer cells for cell and gene therapy

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KR20230017799A true KR20230017799A (ko) 2023-02-06

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US (1) US20220154215A1 (enExample)
EP (1) EP4150097A1 (enExample)
JP (1) JP2023526348A (enExample)
KR (1) KR20230017799A (enExample)
CA (1) CA3183599A1 (enExample)
WO (1) WO2021231884A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12357704B2 (en) 2019-05-06 2025-07-15 Thomas Malcolm Tailored hypoimmune nanovesicular delivery systems for cancer tumors
US12054738B2 (en) 2020-07-30 2024-08-06 Shape Therapeutics Inc. Stable cell lines for inducible production of rAAV virions
JP2024537896A (ja) 2021-10-18 2024-10-16 リジェネロン・ファーマシューティカルズ・インコーポレイテッド アデノウイルス随伴ウイルスポリヌクレオチドを含む真核細胞
AR127674A1 (es) 2021-10-18 2024-02-21 Regeneron Pharma Células de mamífero que comprenden genes cas9 integrados para producir sitios de integración estables, y células de mamífero que comprenden sitios de integración estables y otros sitios
WO2023230230A1 (en) * 2022-05-25 2023-11-30 Malcolm Thomas Tailored hypoimmunogenic biomimetic nanovesicle delivery system for viral infection

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981276A (en) 1990-06-20 1999-11-09 Dana-Farber Cancer Institute Vectors containing HIV packaging sequences, packaging defective HIV vectors, and uses thereof
CA2344208A1 (en) * 2001-04-30 2002-10-30 Oxford Biomedica (Uk) Limited Method
WO2013076309A1 (en) * 2011-11-24 2013-05-30 Genethon Scalable lentiviral vector production system compatible with industrial pharmaceutical applications
DK3294893T5 (da) * 2015-05-13 2024-10-07 Csl Behring Gene Therapy Inc Bioproduktion af lentivirale vektorer
FR3044016A1 (fr) * 2015-11-24 2017-05-26 Glaxosmithkline Ip Dev Ltd Lignees cellulaires stables pour la production retrovirale
GB201706121D0 (en) * 2017-04-18 2017-05-31 Glaxosmithkline Ip Dev Ltd Stable cell lines for retroviral production
JP7470119B2 (ja) * 2018-08-24 2024-04-17 シーエスエル ベーリング ジーン セラピー インコーポレイテッド 無血清培地におけるベクター産生

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CA3183599A1 (en) 2021-11-18
JP2023526348A (ja) 2023-06-21
US20220154215A1 (en) 2022-05-19
EP4150097A1 (en) 2023-03-22
WO2021231884A1 (en) 2021-11-18

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