KR20220128650A - Bcma-유도된 세포 면역요법 조성물 및 방법 - Google Patents

Bcma-유도된 세포 면역요법 조성물 및 방법 Download PDF

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KR20220128650A
KR20220128650A KR1020227028061A KR20227028061A KR20220128650A KR 20220128650 A KR20220128650 A KR 20220128650A KR 1020227028061 A KR1020227028061 A KR 1020227028061A KR 20227028061 A KR20227028061 A KR 20227028061A KR 20220128650 A KR20220128650 A KR 20220128650A
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seq
bcma
domain
chimeric antigen
antigen receptor
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Korean (ko)
Inventor
카냐 락쉬미 라잔감
제임스 바나비 트레이거
루쑤안 구오 버렌
차오 구오
알렉산드라 레이다 리아나 라제틱
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엔카르타, 인크.
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    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • A61K2239/27—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by targeting or presenting multiple antigens
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  • Developmental Biology & Embryology (AREA)
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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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KR1020227028061A 2020-01-13 2021-01-11 Bcma-유도된 세포 면역요법 조성물 및 방법 Pending KR20220128650A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062960285P 2020-01-13 2020-01-13
US62/960,285 2020-01-13
PCT/US2021/012977 WO2021146147A1 (en) 2020-01-13 2021-01-11 Bcma-directed cellular immunotherapy compositions and methods

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KR20220128650A true KR20220128650A (ko) 2022-09-21

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US (1) US20230028399A1 (https=)
EP (1) EP4090337A4 (https=)
JP (1) JP2023512452A (https=)
KR (1) KR20220128650A (https=)
CN (1) CN115279381A (https=)
AU (1) AU2021207795A1 (https=)
CA (1) CA3164666A1 (https=)
IL (1) IL294518A (https=)
MX (1) MX2022008638A (https=)
WO (1) WO2021146147A1 (https=)

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BR112019019917A2 (pt) 2017-03-27 2020-04-22 Nat Univ Singapore receptores quiméricos nkg2d truncados e seus usos em imunoterapia de células exterminadoras naturais
EP3749685A4 (en) 2018-02-09 2021-12-22 National University of Singapore ACTIVATOR CHEMERIC RECEPTORS AND THEIR USES IN NATURAL KILLING CELL IMMUNOTHERAPY
JP7334985B2 (ja) 2018-04-02 2023-08-29 ナショナル ユニヴァーシティー オブ シンガポール 免疫細胞で発現される膜結合抗サイトカイン非シグナル伝達バインダーによるヒトサイトカインの中和
EP3844186A4 (en) 2018-08-29 2022-08-17 National University of Singapore METHOD OF SPECIFIC STIMULATION OF SURVIVAL AND EXPANSION OF GENETICALLY MODIFIED IMMUNE CELLS
EP3773918A4 (en) 2019-03-05 2022-01-05 Nkarta, Inc. CD19 DIRECTED CHIMERIC ANTIGEN RECEPTORS AND THEIR USES IN IMMUNOTHERAPY
US20250034268A1 (en) * 2021-12-07 2025-01-30 Innovent Biologics (Suzhou) Co., Ltd. Antibody binding to bcma and use thereof
WO2025171383A2 (en) 2024-02-09 2025-08-14 Dispatch Biotherapeutics, Inc. Engineered cancer antigens and related methods and uses
WO2025171388A1 (en) 2024-02-09 2025-08-14 Dispatch Biotherapeutics, Inc. Engineered cancer antigens with modified domains and related methods and uses
WO2026006767A1 (en) 2024-06-28 2026-01-02 Dispatch Biotherapeutics, Inc. Tethered il-9/il-9r and related engineered cells and methods

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DK2956175T3 (da) * 2013-02-15 2017-11-27 Univ California Kimærisk antigenreceptor og fremgangsmåder til anvendelse deraf
BR112017001183A2 (pt) * 2014-07-21 2017-11-28 Novartis Ag tratamento de câncer usando receptor de antígeno quimérico anti-bcma humanizado
GB201503742D0 (en) * 2015-03-05 2015-04-22 Ucl Business Plc Chimeric antigen receptor
US11655452B2 (en) * 2015-06-25 2023-05-23 Icell Gene Therapeutics Inc. Chimeric antigen receptors (CARs), compositions and methods of use thereof
BR112019019917A2 (pt) * 2017-03-27 2020-04-22 Nat Univ Singapore receptores quiméricos nkg2d truncados e seus usos em imunoterapia de células exterminadoras naturais
EP3749770B9 (en) * 2018-02-09 2025-12-17 The U.S.A. as represented by the Secretary, Department of Health and Human Services Tethered interleukin-15 and interleukin-21
TWI890660B (zh) * 2018-06-13 2025-07-21 瑞士商諾華公司 Bcma 嵌合抗原受體及其用途
CN109320615B (zh) * 2018-09-25 2023-09-22 上海恒润达生生物科技股份有限公司 靶向新型bcma的嵌合抗原受体及其用途
EP3773918A4 (en) * 2019-03-05 2022-01-05 Nkarta, Inc. CD19 DIRECTED CHIMERIC ANTIGEN RECEPTORS AND THEIR USES IN IMMUNOTHERAPY
AU2020288829A1 (en) * 2019-06-04 2021-12-02 Nkarta, Inc. Combinations of engineered natural killer cells and engineered T cells for immunotherapy

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CN115279381A (zh) 2022-11-01
US20230028399A1 (en) 2023-01-26
WO2021146147A1 (en) 2021-07-22
EP4090337A1 (en) 2022-11-23
AU2021207795A1 (en) 2022-07-28
IL294518A (en) 2022-09-01
JP2023512452A (ja) 2023-03-27
CA3164666A1 (en) 2021-07-22
EP4090337A4 (en) 2024-04-24
MX2022008638A (es) 2022-08-08

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