KR20220115313A - Antibacterial and deodorant cosmetic composition containing Pinus thunbergii extract as an active ingredient - Google Patents

Antibacterial and deodorant cosmetic composition containing Pinus thunbergii extract as an active ingredient Download PDF

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KR20220115313A
KR20220115313A KR1020210019163A KR20210019163A KR20220115313A KR 20220115313 A KR20220115313 A KR 20220115313A KR 1020210019163 A KR1020210019163 A KR 1020210019163A KR 20210019163 A KR20210019163 A KR 20210019163A KR 20220115313 A KR20220115313 A KR 20220115313A
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cosmetic composition
deodorant
antibacterial
extract
active ingredient
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김종만
홍혜진
현홍준
김대웅
오화정
김대진
신소영
부경흥
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엠제이 주식회사
(주) 우수컨버팅
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9755Gymnosperms [Coniferophyta]
    • A61K8/9767Pinaceae [Pine family], e.g. pine or cedar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00Anti-perspirants or body deodorants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations

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Abstract

The present invention relates to a deodorant and antibacterial cosmetic composition containing a Pinus thunbergii extract as an active ingredient, which suppresses body odor and inhibits the growth of harmful bacteria on the skin that causes odor. The deodorant and antibacterial cosmetic composition of the present invention is safe for the skin and suppresses the body odor caused by the action of germs due to sweat to effectively deodorize unpleasant body odor. In addition, the deodorant and antibacterial cosmetic composition inhibits the proliferation of the harmful bacteria on the skin that can cause the skin odor to have an excellent antibacterial effect in removing odors generated from the skin.

Description

곰솔추출물을 유효성분으로 함유하는 소취 및 항균성 화장료 조성물{Antibacterial and deodorant cosmetic composition containing Pinus thunbergii extract as an active ingredient}Antibacterial and deodorant cosmetic composition containing Pinus thunbergii extract as an active ingredient}

본 발명은 곰솔추출물을 유효성분으로 함유하는 소취 및 항균성 화장료 조성물에 관한 것이며, 구체적으로는 체취를 억제하고, 냄새를 유발하는 피부 상재 유해균의 증식을 억제하는 곰솔추출물을 유효성분으로 함유하는 소취 및 항균성 화장료 조성물에 관한 것이다.The present invention relates to a deodorizing and antibacterial cosmetic composition containing a gomsol extract as an active ingredient, and more specifically, to a deodorant and It relates to an antibacterial cosmetic composition.

일반적으로 체취는 몸 전체에 분포하는 에크린 땀샘(eccrine sweat gland)과 겨드랑이 등 체모가 많은 부분에 분포하는 아포크린 땀샘(apocrine sweat gland) 등에서 분비되는 땀에 포함되어 있는 지방과 단백질, 피지, 오염물 등이 피부에 상재하고 있는 미생물이나 세균 등에 의해 분해되는 과정에서 발생하며, 신체 부위에 따라 냄새 및 유발원인이 상이한 특성이 있으며, 아이, 남성, 여성, 노인 등 성별 및 나이에 따라 각기 다른 특이취를 나타내고 있다.In general, body odor comes from fat, protein, sebum, and pollutants contained in sweat secreted from eccrine sweat glands distributed throughout the body and apocrine sweat glands distributed in areas with a lot of body hair such as armpits. It occurs in the process of being decomposed by microorganisms or bacteria residing on the skin, and has different odors and triggers depending on the body part. is indicating

특히, 격렬한 운동이나 스트레스로 인한 과도한 땀과 피지 분비, 느끼하고 기름진 음식 섭취에 따른 단백질과 지방이 땀과 함께 분비 등이 심한 체취의 원인이 되며, 향취가 강한 양파, 마늘, 카레와 같은 식품이나 카페인이 많이 포함된 커피, 초콜렛, 콜라, 몸 속에 단백질과 지방을 늘려주는 음주와 그 자체가 쾌쾌한 냄새를 몸에 배게 하는 흡연 등도 불쾌감을 주는 체취의 원인이 된다.In particular, excessive sweat and sebum secretion due to strenuous exercise or stress, and protein and fat secretion along with sweat from eating greasy and oily food are the causes of severe body odor. Caffeine-rich coffee, chocolate, cola, alcohol that increases protein and fat in the body, and smoking, which in itself has a pleasant smell, can also cause unpleasant body odors.

체취를 제어하는 방법으로 흡착성분에 의한 탈취발명, 향을 이용하여 체취를 차단하는 마스킹 방법, 소취제를 체취성분과 반응시켜 소취를 제거는 방법 등 다양한 방법이 시용되고 있으나 상기 각각의 소취방법은 서로 다른 장단점이 있다.As a method of controlling body odor, various methods are being used, such as the invention of deodorization by an adsorption component, a masking method that blocks body odor using fragrance, and a method of removing deodorization by reacting a deodorant with a body odor component. There are other advantages.

그리고 천연재료를 사용하여 소취하는 기술과 관련하여 선행기술로 예를 들면, 특허문헌 1에 회향을 메탄올과 물 또는 에탄올과 물로 추출한 회향 추출물을 유효성분으로 함유하는 소취제를 개시하고 있으며, 특허문헌 2에 압력 200 ~ 300bar 및 온도 45 ~ 55℃ 추출조건의 초임계 이산화탄소 추출물로서의 쥐방울덩굴과의 민족두리풀 또는 족두리풀의 세신 추출물과, 마 또는 참마의 수추출물을 포함하며; 세신 추출물이 메틸유제놀을 138.00 ~ 178.93mg/g 추출오일의 양으로 포함하는 세신 및 마 추출물을 함유하는 소취, 보습, 항산화 및, 항균 화장료 조성물을 개시하고 있다.And in relation to the technology of deodorizing using natural materials, as a prior art, for example, Patent Document 1 discloses a deodorant containing fennel extract obtained by extracting fennel with methanol and water or ethanol and water as an active ingredient, Patent Document 2 At a pressure of 200 ~ 300bar and a temperature of 45 ~ 55 ℃ as a supercritical carbon dioxide extract under the extraction conditions, including the extract of the sessin extract and the extract of the yam or yam of the genus oleracea of the family Grapevine family; Disclosed is a deodorizing, moisturizing, antioxidant and antibacterial cosmetic composition containing sesin and hemp extracts, wherein the sesin extract contains methyleugenol in an amount of 138.00 to 178.93 mg/g extracted oil.

또 특허문헌 3에는 당귀 1 ~ 3중량%, 녹차 1 ~ 3중량%, 탄산수소나트륨 1 ~ 3중량%, 감국 10.5 ~ 15중량%, 계피 1 ~ 10.5중량%, 팔각회향 0.1 ~ 0.5중량%, 정제수 56 ~ 69.5중량%, 로즈마리하이드로졸 1 ~ 10중량%, 페파민트오일은 0.1 ~ 0.3중량%, 폴리소르베이트20은 0.11 ~ 0.3중량%로 마련되는 것을 특징으로 하는 폴리페놀 성분을 이용한 천연 소취제 조성물을 개시하고 있다.In addition, in Patent Document 3, Angelica 1-3% by weight, green tea 1-3% by weight, sodium bicarbonate 1-3% by weight, chrysanthemum 10.5-15% by weight, cinnamon 1-10.5% by weight, octagonal fennel 0.1-0.5% by weight, A natural deodorant composition using a polyphenol component, characterized in that 56 to 69.5% by weight of purified water, 1 to 10% by weight of rosemary hydrosol, 0.1 to 0.3% by weight of peppermint oil, and 0.11 to 0.3% by weight of polysorbate 20 is starting.

본 발명의 발명자는 곰솔의 추출물이 소취성분으로 유효한 활성을 갖는 것을 확인하고 본 발명을 완성하였다.The inventor of the present invention confirmed that the extract of gomsol has an effective activity as a deodorizing component and completed the present invention.

KRUS 10-012248810-0122488 B1B1 KRUS 10-182444910-1824449 B1B1 KRUS 10-212083510-2120835 B1B1

본 발명에서 해결하고자 하는 과제는 체취를 억제하고, 냄새를 유발하는 피부 상재 유해균의 증식을 저해하는 곰솔추출물을 유효성분으로 함유하는 소취 및 항균성 화장료 조성물에 관한 것이다.The problem to be solved by the present invention relates to a deodorizing and antibacterial cosmetic composition containing as an active ingredient a gomsol extract, which suppresses body odor and inhibits the growth of harmful bacteria on the skin that causes odor.

본 발명에서 과제의 해결수단으로 곰솔추출물을 유효성분으로 함유하는 소취 및 항균성 화장료 조성물은 화장료 성분 총중량에 대하여 유효성분으로 곰솔추출물을 1 ~ 6중량% 함유하는 것으로 이루어진다.As a means of solving the problem in the present invention, the deodorizing and antibacterial cosmetic composition containing gomsol extract as an active ingredient consists of containing 1 to 6% by weight of gomsol extract as an active ingredient with respect to the total weight of the cosmetic ingredients.

상기 본 발명에 따른 곰솔추출물을 유효성분으로 함유하는 소취 및 항균성 화장료 조성물은 체취억제용, 땀 억제용, 각질 제거용, 또는 피부 보습용 화장료에 적용될 수 있다.The deodorant and antibacterial cosmetic composition containing the Gomsol extract according to the present invention as an active ingredient may be applied to a cosmetic for body odor control, sweat suppression, exfoliation, or skin moisturizing.

또 화장료 제조의 통상의 방법에 따라 제조되는 것으로 이루어지며, 예를 들면 약학적, 화장학적 또는 피부학적으로 허용 가능한 부형제와 함께 유연화장수, 영양화장수, 영양크림, 마사지크림, 에센스, 앰플, 젤, 아이크림, 클렌징크림, 클렌징폼, 클렌징워터, 팩, 스프레이 및 파우더로 이루어진 군에서 선택된 하나 이상으로 제형 등에 적용되는 것으로 이루어진다.In addition, it consists of being manufactured according to a conventional method for manufacturing cosmetics, and for example, softening lotion, nutrient lotion, nourishing cream, massage cream, essence, ampoules, gel, One or more selected from the group consisting of eye cream, cleansing cream, cleansing foam, cleansing water, pack, spray, and powder, and the like is applied to the formulation.

본 발명의 화장료 조성물은 땀으로 인해 균이 작용하여 발생하는 체취를 억제함으로써 체취에 대한 불쾌한 체취를 효과적으로 소취하면서 피부 냄새를 유발할 수 있는 피부 상재 유해균의 증식을 저해함으로써 피부에 발생되는 악취를 제거하는데 우수한 항균효과가 있다.The cosmetic composition of the present invention effectively deodorizes unpleasant body odors by suppressing body odors caused by the action of bacteria due to sweat, while inhibiting the proliferation of harmful bacteria that can cause skin odors, thereby removing odors generated on the skin. It has excellent antibacterial effect.

도 1은 본 발명에 따른 실험예 1에서 곰솔추출물의 가스검지관법에 따른 소취 정도 결과를 나타낸 도표1 is a table showing the results of the degree of deodorization according to the gas detection tube method of Gomsol extract in Experimental Example 1 according to the present invention;

이하에서는 발명을 실시하기 위한 구체적인 내용, 실시예 및 시험예를 통하여 본 발명을 구체적으로 설명하지만 실시예의 기재에 의해 본 발명이 한정되는 것은 아니다.Hereinafter, the present invention will be described in detail through specific contents, examples, and test examples for carrying out the invention, but the present invention is not limited by the description of the examples.

본 발명의 곰솔추출물을 유효성분으로 함유하는 소취 및 항균성 화장료 조성물은 화장료 성분 총중량에 대하여 유효성분으로 곰솔추출물을 1 ~ 6중량% 함유하는 것으로 이루어진다.The deodorant and antibacterial cosmetic composition containing the Gomsol extract of the present invention as an active ingredient consists of containing 1 to 6% by weight of the Gomsol extract as an active ingredient based on the total weight of the cosmetic ingredients.

본 발명에서 선택하는 곰솔(학명:Pinus thunbergii)은 해송(海松)·흑송(黑松)·검솔·숫솔·완솔이라고도 칭하고 있으며, 줄기와 가지가 검은 빛을 띠는 소나무속의 종이며, 일본과 한반도 중부 이남 해변이나 해안 산지에서 잘 자라고, 늘푸른·바늘잎·큰키나무이다.The gom pine (scientific name: Pinus thunbergii ) selected in the present invention is also called sea pine, black pine, sword pine, bristle, and pine pine, and is a species of the genus of pine with black stems and branches, and is a species of the genus of pine trees in Japan and the Korean Peninsula. It grows well on the beaches south of the central part or in the coastal mountains, and it is an evergreen, needleleaf, and tall tree.

상기 곰솔에 함유된 성분으로 잎에는 아스크로빈산, 카르티노이드, 피토스테린, 세틸알콜, 유니페르산을 주성분으로한 에스톨리드형랍, 헥사데칸2디올, 두어 데칸12디올, 트리아콘탄올 정유가 있으며, 정유는 -피넨, β-피넨, 캄펜, 디펜텐, 보르네올, 보르닐아세테이트, 세스쿠이테르펜, 세스쿠이테르펜알콜, 티데르펜동이 있고, 뿌리에는 피넨을 주성분으로 하고 디펜텐, 캄펜등으로 이루어진 정유가 있으며, 목부에는 피노실빈, 피노실빈-모노메칠에스테르, 피노쨈브린, 피노반크신 등이 있고, 껍질에서 딴 송진이는 정유, 수지가 있다, 수지는 레보피마르산, 덱스트로피마르산, 아비엔틴산, 네오아비에틴산, 이소덱스트로피마르산이 존재하며, 류마치스, 좌골신경통, 방광염 그리고 각종염의 치료제로 사용되고 있다.As the ingredients contained in Gomsol, the leaves contain ascrobic acid, carotenoids, phytosterin, cetyl alcohol, and estolide wax containing uniperic acid as main ingredients, hexadecane 2diol, dua decane 12diol, triacontanol essential oil Essential oils include -pinene, β-pinene, campene, dipentene, borneol, bornyl acetate, sescuiterpene, sesquiterpene alcohol, and tiderpene copper. There are essential oils consisting of, etc., and in the throat there are pinosylvin, pinosylvin-monomethyl ester, pinojambrin, and pinovankcin. Tropic acid, abientic acid, neoabietic acid, and isodextropimaric acid exist, and are used as a treatment for rheumatism, sciatica, cystitis, and various inflammations.

본 발명에 따른 상기 곰솔은 나무, 잎, 가지, 줄기껍질 및 뿌리를 모두 포함하며, 건조된 잎과 줄기를 선택하는 것이 바람직하다.The gom brush according to the present invention includes all of a tree, a leaf, a branch, a stem bark, and a root, and it is preferable to select dried leaves and stems.

상기 곰솔추출물은 건조된 잎과 줄기의 분쇄물을 물 또는 C1 ~ C4의 저급알코올 및 이들의 혼합물을 추출용매로 하여 추출하고, 농축 및 건조하는 것으로 이루어지며 추출용매는 에탄올이 바람직하다.The Gomsol extract consists of extracting, concentrating and drying the dried leaves and stems using water or C 1 to C 4 lower alcohol and a mixture thereof as an extraction solvent, and the extraction solvent is ethanol.

상기 곰솔추출물의 추출과정을 보다 구체적으로 설명하면, 건조된 곰솔의 잎과 줄기의 분쇄물을 추출용매로 20 ~ 100℃, 10 ~ 48시간 추출하며, 바람직하게는 20 ~ 40℃, 15 ~ 30시간 추출하여 농축 및 건조하는 것으로 이루어지며 상기 추출과정은 1 ~ 5회반복하여 추출하는 것이 바람작하다.When explaining the extraction process of the Gomsol extract in more detail, the dried leaves and stems of the dried Gomsol extract are extracted with an extraction solvent at 20 to 100° C. for 10 to 48 hours, preferably at 20 to 40° C., 15 to 30 It consists of time extraction, concentration and drying, and the extraction process is preferably repeated 1 to 5 times for extraction.

상기 농축방법은 진공감압농축기를 이용한 감압농축 또는 진공회전증발기를 이용하여 농축하는 것이 바람직하나 이에 한정하지 않으며 또한 상기 건조방법은 감압건조, 진공건조, 비등건조, 분무건조 또는 동결건조 등이이 바람직하지만 이에 한정하지 않는다.The concentration method is preferably reduced pressure concentration using a vacuum concentrator or concentration using a vacuum rotary evaporator, but is not limited thereto, and the drying method is preferably reduced pressure drying, vacuum drying, boiling drying, spray drying or freeze drying, etc. It is not limited to this.

그리고 상기 본 발명에 따른 곰솔추출물을 유효성분으로 함유하는 소취 및 항균성 화장료 조성물은 체취억제용, 땀 억제용, 각질 제거용, 또는 피부 보습용 화장료에 적용된다.And the deodorant and antibacterial cosmetic composition containing the Gomsol extract according to the present invention as an active ingredient is applied to a cosmetic for body odor control, sweat suppression, exfoliation, or skin moisturizing.

또 화장료 제조의 통상의 방법에 따라 제조되는 것으로 이루어지며, 예를 들면 약학적, 화장학적 또는 피부학적으로 허용 가능한 부형제와 함께 유연화장수, 영양화장수, 영양크림, 마사지크림, 에센스, 앰플, 젤, 아이크림, 클렌징크림, 클렌징폼, 클렌징워터, 팩, 스프레이 및 파우더로 이루어진 군에서 선택된 하나 이상으로 제형 등에 적용되는 것으로 이루어진다.In addition, it consists of being manufactured according to a conventional method for manufacturing cosmetics, and for example, softening lotion, nutrient lotion, nourishing cream, massage cream, essence, ampoules, gel, One or more selected from the group consisting of eye cream, cleansing cream, cleansing foam, cleansing water, pack, spray, and powder, and the like is applied to the formulation.

이하에서는 <실시예> 및 <시험예>를 통하여 본 발명을 보다 구체적으로 설명하기로 한다.Hereinafter, the present invention will be described in more detail through <Examples> and <Test Examples>.

<실시예 1><Example 1>

건조된 곰솔을 분쇄기로 미세하게 분세한 분말을 준비된 추출기에 투입하고, 70중량% 농도의 에탄올을 원료대비 3배 정도의 량으로 투입하여 24시간 교반하면서 침지시켜 침출한 후 여과하여 추출물을 얻었다.The dried gomsol powder was finely divided by a grinder, and then, 70% by weight of ethanol was added in an amount about three times that of the raw material, immersed while stirring for 24 hours, leached, and filtered to obtain an extract.

상기 추출물을 농축기(R-100, BUCHI)를 이용하여 40℃에서 감압 농축하여 곰솔추출물을 제조하였다.The extract was concentrated under reduced pressure at 40° C. using a concentrator (R-100, BUCHI) to prepare a Gomsol extract.

<시험예 1> 소취효능 평가 <Test Example 1> Deodorization efficacy evaluation

가스검지관법을 이용하여 실내온도 22℃, 상대습도 45%의 조건에서 상기 <실시예 1>에서 제조한 곰솔추출물을 시료로 하여 악취성분에 대한 제거(소취) 능력을 아래와 같이 시험하였다.The ability to remove (deodorize) odor components was tested as follows using the Gomsol extract prepared in <Example 1> as a sample at a room temperature of 22° C. and a relative humidity of 45% using the gas detector tube method.

3ℓ 테들러백 내부로 암모니아를 주입하여 내부의 농도가 100㎍/㎖가 되도록 가스검지기로 측정하여 이를 초기농도로 하고, 초기농도를 맞춘 테들러백 내부로 곰솔추출물 시료 1㎖를 주입한 후 밀봉하였다.Ammonia is injected into the 3ℓ Tedler bag and measured with a gas detector so that the inner concentration becomes 100 μg/ml, and this is used as the initial concentration. did.

초기, 0.5시간, 1시간, 1.5시간, 2시간 경과 시점의 가스농도를 가스검지기로 정확히 측정하였다. 곰솔추출물 시료를 주입하지 않고, 동일하게 시험하여 바탕시험(Blank test)으로 하였으며, 시험결과를 아래 [표 1] 및 [도 1]로 나타내었다.The gas concentration at the initial, 0.5 hour, 1 hour, 1.5 hour, and 2 hours elapsed time was accurately measured with a gas detector. Without injecting the Gomsol extract sample, the same test was used as a blank test, and the test results are shown in [Table 1] and [Fig. 1] below.

구분division 소취율(%): 가스검지관법Deodorization rate (%): gas detection tube method 30분 경과30 minutes passed 60분경과 60 minutes elapsed 90분경과90 minutes passed 120분경과120 minutes elapsed 실시예 1Example 1 99초과more than 99 99초과more than 99 99초과more than 99 99초과more than 99

상기 [표 1] 및 첨부한 [도 1]에 나타낸 바와 같이 곰솔추출물이 0.5시간 경과 후부터 높은 가스 제거능력을 보였으며, 이로부터 곰솔추출물의 소취효능이 우수한 것을 확인할 수 있다.As shown in [Table 1] and the attached [Fig. 1], the Gomsol extract showed high gas removal ability after 0.5 hours, and from this, it can be confirmed that the Gomsol extract has excellent deodorizing effect.

<시험예 2> 항균활성 평가<Test Example 2> Antimicrobial activity evaluation

2배 희석법(two fold-dilution method)을 이용하여 피부 상재균에 대한 최소저해농도(MIC, Minimum inhibitory concentration)를 측정하여 항균력을 평가하였다.Antimicrobial activity was evaluated by measuring the minimum inhibitory concentration (MIC) against the skin flora using the two fold-dilution method.

시험균주로는 스테필로코커스 아우레우스(Staphylococcus aureus; ATCC 6538), 스테필로코커스 에피더미디스(Staphylococcus epidermidis; ATCC 12228)를 대상으로 실험에 사용하였다.As the test strain, Staphylococcus aureus (ATCC 6538) and Staphylococcus epidermidis (ATCC 12228) were used for the test.

상기 MIC 측정방법에서는 시료의 농도는 1,000ppm으로 진행하였으며, 두 배씩 묽히면서 시료를 포함하는 배지를 100㎕ 넣어준 후, 균 현탁액의 농도를 조절하여 100㎕ 씩 넣어준다. 37℃에서 24시간 배양 후, 균의 증식이 나타나지 않는 최소농도를 확인하고 그 결과를 아래 [표 2]에 나타내었다.In the MIC measurement method, the concentration of the sample was 1,000 ppm, and 100 μl of the medium containing the sample was added while diluting twice, and then, the concentration of the bacterial suspension was adjusted and 100 μl was added. After culturing at 37° C. for 24 hours, the minimum concentration at which the growth of bacteria does not appear was confirmed, and the results are shown in [Table 2] below.

구분division 시료의 농도: %(v/v)Concentration of sample: % (v/v) S. aureus(황색포도상구균) S. aureus (Staphylococcus aureus) S.epidermidis(표피포도상구균) S. epidermidis (Staphylococcus epidermidis) 실시예 1Example 1 0.7810.781 1.5621.562

상기 [표 2]에 나타낸 바와 같이 곰솔추출물은 황색포도상구균에서 0.781%, 표피포도상구균에서 1.562%에서 항균효과가 있는 것을 알 수 있으며, 이로부터 본 발명에 따른 곰솔추출물을 포함하는 화장료 조성물이 땀에 의해 발생하는 특유의 채취를 효과적으로 억제할 수 있는 예측할 수가 있다.As shown in [Table 2], it can be seen that the Gomsol extract has an antibacterial effect at 0.781% in Staphylococcus aureus and 1.562% in Staphylococcus epidermis, and from this, the cosmetic composition containing the Gomsol extract according to the present invention is sweaty. It can be predicted that can effectively suppress the specific sampling caused by

<실시예 2> <Example 2>

상기 <실시예 1>에서 제조된 곰솔추출물을 유효성분으로 하여 아래 [표 3]에 나타낸 조성성분 및 비율에 따라 유연화장수 타입의 화장품을 제조하였다.Using the Gomsol extract prepared in <Example 1> as an active ingredient, a softening lotion type cosmetic was prepared according to the composition ingredients and ratios shown in [Table 3] below.

조성성분composition 조성비(중량%) Composition ratio (wt%) 곰솔추출물Gomsol Extract 66 에탄올ethanol 66 폴리옥시에틸렌경화피마자유Polyoxyethylene hydrogenated castor oil 1.01.0 파라옥시안식향산메칠methyl paraoxybenzoate 22 글리세린glycerin 5.05.0 1,3-부틸렌글리콜1,3-butylene glycol 6.06.0 향료Spices 적량appropriate amount 정제수Purified water To 100To 100

<시험예 3> <Test Example 3>

상기 <실시예 2>의 유연화장수 타입의 화장품에 대하여 피부자극성 정도를 평가하기 위해 아래와 같이 인체에 대한 첩포시험(patch test)을 실시하였다.In order to evaluate the degree of skin irritation for the softening lotion type cosmetics of <Example 2>, a patch test was performed on the human body as follows.

건강한 성인 남녀 30명을 대상으로 등부위에 각각의 시료를 25㎕씩 첩포하고 24시간 후 핀챔버를 제거한 후 30분, 24시간, 48시간 경과한 다음 육안으로 피부상태를 확인하고, 아래 나타낸 [표 4]의 국제접촉피부염연구회(International Contact Dermatitis Research Group:ICDRG)의 판정기준에 따라 판단하고 그 결과를 아래 [표 5]에 나타내었다. Apply 25 μl of each sample to the back of 30 healthy adult males and females, remove the pin chamber after 24 hours, and check the skin condition visually after 30 minutes, 24 hours, and 48 hours have elapsed. 4], and the results are shown in [Table 5] below.

기호sign 판정기준Criteria -- Negativenegative 무자극non-irritant ±± Doubtful or slight and erythemaDoubtful or slight and erythema 미자극unstimulated ++ Erythena + indurationErythena + induration 경자극mild stimulation ++++ Erythema + induration + vesicleErythema + induration + vesicle 중자극central stimulus ++++++ Erythema + induration + bullaeErythema + induration + bullae 강자극strong stimulus

시료sample 첩포 30분 후
판독
30 minutes after application
reading
첩포 24시간 후
판독
24 hours after application
reading
첩포 48시간 후
판독
48 hours after application
reading
평균Average 판정Judgment
-- ±± -- ±± -- ±± 실시예2Example 2 30명30 people -- 30명30 people -- 30명30 people -- 0.000.00 무자극non-irritant

상기 [표 5]에 나타낸 바와 같이, 본 발명의 곰솔추출물을 유효성분으로 함유하는 화장료는 피부자극도가 매우 낮은 것으로 확인할 수가 있었다.As shown in [Table 5], it was confirmed that the cosmetic containing the Gomsol extract of the present invention as an active ingredient had very low skin irritation.

Claims (5)

곰솔추출물을 유효성분으로 함유하는 것을 특징으로 하는 소취 및 항균성 화장료 조성물.A deodorant and antibacterial cosmetic composition comprising Gomsol extract as an active ingredient. 청구항 1에 있어서, 유효성분이 화장료 총중량에 대하여 1 ~ 6중량% 함유하는 것을 특징으로 하는 소취 및 항균성 화장료 조성물.The deodorant and antibacterial cosmetic composition according to claim 1, wherein the active ingredient is contained in an amount of 1 to 6% by weight based on the total weight of the cosmetic. 청구항 2에 있어서, 곰솔추출물은 나무, 잎, 가지, 줄기껍질 및 뿌리를 모두 포함하는 곰솔을 물 또는 C1 ~ C4의 저급알코올 및 이들의 혼합물을 추출용매로 하여 20 ~ 100℃, 10 ~ 48시간 추출하고 농축 및 건조한 것을 특징으로 하는 소취 및 항균성 화장료 조성물.The method according to claim 2, Gom pine extract is 20 ~ 100 ℃, 10 ~ by using Gom pine including all trees, leaves, branches, stem bark and roots with water or C 1 ~ C 4 lower alcohol and a mixture thereof as an extraction solvent A deodorant and antibacterial cosmetic composition, characterized in that it is extracted for 48 hours, concentrated and dried. 청구항 3에 있어서, 화장료 조성물이 체취억제용, 땀 억제용, 각질 제거용, 또는 피부 보습용에 적용되는 것을 특징으로 하는 소취 및 항균성 화장료 조성물.The deodorant and antibacterial cosmetic composition according to claim 3, wherein the cosmetic composition is applied for body odor suppression, sweat suppression, exfoliation, or skin moisturizing. 청구항 4에 있어서, 화장료 조성물이 유연화장수, 영양화장수, 영양크림, 마사지크림, 에센스, 앰플, 젤, 아이크림, 클렌징크림, 클렌징폼, 클렌징워터, 팩, 스프레이 및 파우더 중에서 선택된 어느 하나의 제형인 것을 특징으로 하는 소취 및 항균성 화장료 조성물.The method according to claim 4, wherein the cosmetic composition is a formulation selected from softening lotion, nutrient lotion, nourishing cream, massage cream, essence, ampoule, gel, eye cream, cleansing cream, cleansing foam, cleansing water, pack, spray and powder. Deodorizing and antibacterial cosmetic composition, characterized in that.
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20100122488A (en) 2008-02-29 2010-11-22 에이제토 엘렉토로닉 마티리알즈 가부시키가이샤 Method for formation of siliceous film and siliceous film formed by the method
KR101824449B1 (en) 2015-07-27 2018-02-02 주식회사 에코마인 Cosmetic composition comprising extracts of asarum and chinese dioscorea having deodorizing, moisturizing, antioxidative, and antibacterial effect
KR102120835B1 (en) 2018-12-24 2020-06-09 재단법인 경남한방항노화연구원 Natural deodorant composition using polyphenol

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20100122488A (en) 2008-02-29 2010-11-22 에이제토 엘렉토로닉 마티리알즈 가부시키가이샤 Method for formation of siliceous film and siliceous film formed by the method
KR101824449B1 (en) 2015-07-27 2018-02-02 주식회사 에코마인 Cosmetic composition comprising extracts of asarum and chinese dioscorea having deodorizing, moisturizing, antioxidative, and antibacterial effect
KR102120835B1 (en) 2018-12-24 2020-06-09 재단법인 경남한방항노화연구원 Natural deodorant composition using polyphenol

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