KR20220079882A - Kv1.3 칼륨 셰이커 채널 차단제로서의 아릴 헤테로시클릭 화합물 - Google Patents

Kv1.3 칼륨 셰이커 채널 차단제로서의 아릴 헤테로시클릭 화합물 Download PDF

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KR20220079882A
KR20220079882A KR1020227013513A KR20227013513A KR20220079882A KR 20220079882 A KR20220079882 A KR 20220079882A KR 1020227013513 A KR1020227013513 A KR 1020227013513A KR 20227013513 A KR20227013513 A KR 20227013513A KR 20220079882 A KR20220079882 A KR 20220079882A
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cycloalkyl
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파브리지오 지오르다네토
모르텐 외스테르가드 얀센
비쉬와나뜨 요기니
로저 존 스노우
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디.이. 쇼우 리서치, 엘엘씨
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    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
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    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
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    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
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CN113603573A (zh) * 2021-08-09 2021-11-05 苏州求索生物科技有限公司 一种3,5-二氯-2-碘苯甲醚的制备工艺
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