KR20220076508A - 올리고뉴클레오티드 조성물 및 이의 사용 방법 - Google Patents

올리고뉴클레오티드 조성물 및 이의 사용 방법 Download PDF

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KR20220076508A
KR20220076508A KR1020227015085A KR20227015085A KR20220076508A KR 20220076508 A KR20220076508 A KR 20220076508A KR 1020227015085 A KR1020227015085 A KR 1020227015085A KR 20227015085 A KR20227015085 A KR 20227015085A KR 20220076508 A KR20220076508 A KR 20220076508A
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oligonucleotide
oligonucleotides
target
composition
nucleic acid
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Korean (ko)
Inventor
프라샨트 모니안
칙두 샥티 쉬바릴라
수브라마니안 마라판
찬드라 바기스
파차무투 칸다사미
젠리앙 루
휘 유
데이빗 찰스 도넬 버틀러
루치아노 헨리께 아포니
마모루 시미즈
스테퍼니 미셸 스탠들리
데이빗 존 불레이
앤드류 귀자이어 호쓰
지가르 데자이
잭 데이빗 갓프리
하이린 양
나오키 이와모토
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웨이브 라이프 사이언시스 리미티드
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Publication of KR20220076508A publication Critical patent/KR20220076508A/ko
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    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/31—Chemical structure of the backbone
    • C12N2310/314—Phosphoramidates
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/32—Chemical structure of the sugar
    • C12N2310/321—2'-O-R Modification
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/35—Nature of the modification
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/35—Nature of the modification
    • C12N2310/353—Nature of the modification linked to the nucleic acid via an atom other than carbon
    • C12N2310/3533—Halogen

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  • Wood Science & Technology (AREA)
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  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020227015085A 2019-10-06 2020-10-06 올리고뉴클레오티드 조성물 및 이의 사용 방법 Pending KR20220076508A (ko)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201962911334P 2019-10-06 2019-10-06
US62/911,334 2019-10-06
US202062959917P 2020-01-11 2020-01-11
US62/959,917 2020-01-11
US202063022559P 2020-05-10 2020-05-10
US63/022,559 2020-05-10
US202063069696P 2020-08-24 2020-08-24
US63/069,696 2020-08-24
PCT/US2020/054436 WO2021071858A1 (en) 2019-10-06 2020-10-06 Oligonucleotide compositions and methods of use thereof

Publications (1)

Publication Number Publication Date
KR20220076508A true KR20220076508A (ko) 2022-06-08

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KR1020227015085A Pending KR20220076508A (ko) 2019-10-06 2020-10-06 올리고뉴클레오티드 조성물 및 이의 사용 방법

Country Status (11)

Country Link
US (1) US20230220384A1 (https=)
EP (1) EP4022059A4 (https=)
JP (2) JP7766589B2 (https=)
KR (1) KR20220076508A (https=)
CN (1) CN114585737A (https=)
AU (1) AU2020363391A1 (https=)
BR (1) BR112022006205A2 (https=)
CA (1) CA3154768A1 (https=)
IL (1) IL291933A (https=)
MX (1) MX2022004101A (https=)
WO (1) WO2021071858A1 (https=)

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MX2022004101A (es) 2022-04-26
IL291933A (en) 2022-06-01
AU2020363391A1 (en) 2022-03-24
US20230220384A1 (en) 2023-07-13
WO2021071858A1 (en) 2021-04-15
CN114585737A (zh) 2022-06-03
EP4022059A1 (en) 2022-07-06
JP2022551124A (ja) 2022-12-07
CA3154768A1 (en) 2021-04-15
EP4022059A4 (en) 2023-11-01
JP2025165976A (ja) 2025-11-05
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JP7766589B2 (ja) 2025-11-10

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