KR20220061253A - 탄성 폴리머-약물 매트릭스 시스템을 포함하는 방광내 약물 전달 장치 및 방법 - Google Patents

탄성 폴리머-약물 매트릭스 시스템을 포함하는 방광내 약물 전달 장치 및 방법 Download PDF

Info

Publication number
KR20220061253A
KR20220061253A KR1020227013798A KR20227013798A KR20220061253A KR 20220061253 A KR20220061253 A KR 20220061253A KR 1020227013798 A KR1020227013798 A KR 1020227013798A KR 20227013798 A KR20227013798 A KR 20227013798A KR 20220061253 A KR20220061253 A KR 20220061253A
Authority
KR
South Korea
Prior art keywords
lumen
drug
silicone
bladder
matrix system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020227013798A
Other languages
English (en)
Korean (ko)
Inventor
이희진
카렌 다니엘
Original Assignee
타리스 바이오메디컬 엘엘씨
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 타리스 바이오메디컬 엘엘씨 filed Critical 타리스 바이오메디컬 엘엘씨
Priority to KR1020237033481A priority Critical patent/KR20230142816A/ko
Publication of KR20220061253A publication Critical patent/KR20220061253A/ko
Ceased legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0009Making of catheters or other medical or surgical tubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/02General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0216Materials providing elastic properties, e.g. for facilitating deformation and avoid breaking
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2207/00Methods of manufacture, assembly or production
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/10Trunk
    • A61M2210/1078Urinary tract
    • A61M2210/1085Bladder

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
KR1020227013798A 2014-06-26 2015-06-26 탄성 폴리머-약물 매트릭스 시스템을 포함하는 방광내 약물 전달 장치 및 방법 Ceased KR20220061253A (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020237033481A KR20230142816A (ko) 2014-06-26 2015-06-26 탄성 폴리머-약물 매트릭스 시스템을 포함하는 방광내 약물 전달 장치 및 방법

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201462017775P 2014-06-26 2014-06-26
US62/017,775 2014-06-26
KR1020177000765A KR102391761B1 (ko) 2014-06-26 2015-06-26 탄성 폴리머-약물 매트릭스 시스템을 포함하는 방광내 약물 전달 장치 및 방법
PCT/US2015/037887 WO2015200752A1 (en) 2014-06-26 2015-06-26 Intravesical drug delivery devices and methods including elastic polymer-drug matrix systems

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020177000765A Division KR102391761B1 (ko) 2014-06-26 2015-06-26 탄성 폴리머-약물 매트릭스 시스템을 포함하는 방광내 약물 전달 장치 및 방법

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020237033481A Division KR20230142816A (ko) 2014-06-26 2015-06-26 탄성 폴리머-약물 매트릭스 시스템을 포함하는 방광내 약물 전달 장치 및 방법

Publications (1)

Publication Number Publication Date
KR20220061253A true KR20220061253A (ko) 2022-05-12

Family

ID=53524992

Family Applications (4)

Application Number Title Priority Date Filing Date
KR1020227013798A Ceased KR20220061253A (ko) 2014-06-26 2015-06-26 탄성 폴리머-약물 매트릭스 시스템을 포함하는 방광내 약물 전달 장치 및 방법
KR1020227013799A Active KR102486216B1 (ko) 2014-06-26 2015-06-26 탄성 폴리머-약물 매트릭스 시스템을 포함하는 방광내 약물 전달 장치 및 방법
KR1020237033481A Pending KR20230142816A (ko) 2014-06-26 2015-06-26 탄성 폴리머-약물 매트릭스 시스템을 포함하는 방광내 약물 전달 장치 및 방법
KR1020177000765A Active KR102391761B1 (ko) 2014-06-26 2015-06-26 탄성 폴리머-약물 매트릭스 시스템을 포함하는 방광내 약물 전달 장치 및 방법

Family Applications After (3)

Application Number Title Priority Date Filing Date
KR1020227013799A Active KR102486216B1 (ko) 2014-06-26 2015-06-26 탄성 폴리머-약물 매트릭스 시스템을 포함하는 방광내 약물 전달 장치 및 방법
KR1020237033481A Pending KR20230142816A (ko) 2014-06-26 2015-06-26 탄성 폴리머-약물 매트릭스 시스템을 포함하는 방광내 약물 전달 장치 및 방법
KR1020177000765A Active KR102391761B1 (ko) 2014-06-26 2015-06-26 탄성 폴리머-약물 매트릭스 시스템을 포함하는 방광내 약물 전달 장치 및 방법

Country Status (9)

Country Link
US (3) US10737078B2 (enExample)
EP (3) EP4173615A3 (enExample)
JP (3) JP6856380B2 (enExample)
KR (4) KR20220061253A (enExample)
CN (2) CN106456951B (enExample)
AU (4) AU2015279674B2 (enExample)
DK (1) DK3160442T3 (enExample)
ES (2) ES2940478T3 (enExample)
WO (1) WO2015200752A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016176444A1 (en) * 2015-04-29 2016-11-03 Northwestern University 3d printing of biomedical implants
WO2017132372A1 (en) 2016-01-26 2017-08-03 Taris Biomedical Llc Multi-lumen drug delivery devices
NZ748252A (en) 2016-05-06 2025-10-31 Taris Biomedical Llc Method of treating lower tract urothelial cancer
SG10201913998YA (en) 2017-07-25 2020-03-30 Taris Biomedical Llc Methods of treating tumor metastasis
MX2020004771A (es) 2017-11-08 2020-10-19 Taris Biomedical Llc Metodos de tratamiento y terapia de mantenimiento para el cancer de vejiga con gemcitabina.
US20190365645A1 (en) 2018-05-31 2019-12-05 Massachusetts Institute Of Technology Drug delivery articles for gram-level dosing
CN112839653A (zh) 2018-08-01 2021-05-25 塔里斯生物医药公司 使用曲司氯铵治疗膀胱过度活动症的方法
SG11202103505YA (en) * 2018-11-09 2021-05-28 Taris Biomedical Llc Drug delivery devices and systems for local drug delivery to the upper urinary tract
US20240016731A1 (en) * 2020-09-28 2024-01-18 The Regents Of The University Of California Drug Implants Containing Apalutamide and Methods of Use Thereof
TW202339815A (zh) 2021-12-21 2023-10-16 美商塔里斯生物醫學有限責任公司 用於膀胱內裝置的泌尿置放導管
CN115120854B (zh) * 2022-07-04 2023-10-13 奥格生物技术(六安)有限公司 前列腺自然直接给药装置
US20240033249A1 (en) * 2022-07-20 2024-02-01 The Regents Of The University Of California Drug Implants Containing Darolutamide and Methods of Use Thereof
WO2024092159A1 (en) 2022-10-28 2024-05-02 Taris Biomedical Llc Methods of treating bladder cancer with gemcitabine
AU2024249710A1 (en) 2023-04-10 2025-11-20 Taris Biomedical Llc Gemcitabine for use in methods of treating high-risk non-muscle invasive bladder cancer unresponsive to bacillus calmette-guerin therapy
WO2025076007A1 (en) 2023-10-02 2025-04-10 Taris Biomedical Llc Methods of treating high-risk non-muscle invasive bladder cancer unresponsive to bacillus calmette-guérin therapy

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3854480A (en) * 1969-04-01 1974-12-17 Alza Corp Drug-delivery system
US3967618A (en) * 1969-04-01 1976-07-06 Alza Corporation Drug delivery device
US4871542A (en) 1987-04-30 1989-10-03 Ferring Service Center, N.V. Method and apparatus useful for delivering medicinal compositions into the bladder and urinary tract
NZ228382A (en) * 1989-03-17 1992-08-26 Carter Holt Harvey Plastic Pro Drug administering coil-like device for insertion in body cavity of animal
FI95768C (fi) * 1993-06-17 1996-03-25 Leiras Oy Emättimensisäinen antosysteemi
US20060025726A1 (en) * 1996-06-04 2006-02-02 Vance Products Incorporated, D/B/A Cook Urological Incorporated Implantable medical device with pharmacologically active layer
US20060052757A1 (en) * 1996-06-04 2006-03-09 Vance Products Incorporated, D/B/A Cook Urological Incorporated Implantable medical device with analgesic or anesthetic
US20070161968A1 (en) * 1996-06-04 2007-07-12 Vance Products Inc., Dba Cood Urological Inc. Implantable medical device with pharmacologically active ingredient
KR20010006027A (ko) 1997-04-03 2001-01-15 포인트 바이오메디칼 코퍼레이션 방광내 약물 송달 시스템
US6183461B1 (en) 1998-03-11 2001-02-06 Situs Corporation Method for delivering a medication
US7077859B2 (en) 2000-12-22 2006-07-18 Avantec Vascular Corporation Apparatus and methods for variably controlled substance delivery from implanted prostheses
US6752829B2 (en) 2001-01-30 2004-06-22 Scimed Life Systems, Inc. Stent with channel(s) for containing and delivering a biologically active material and method for manufacturing the same
MX2013000002A (es) * 2001-07-27 2013-04-29 Teva Womens Health Inc Metodos de tratamiento de condiciones patologicas asociadas con vejiga hiperactiva.
US8685427B2 (en) * 2002-07-31 2014-04-01 Boston Scientific Scimed, Inc. Controlled drug delivery
US7166133B2 (en) * 2002-06-13 2007-01-23 Kensey Nash Corporation Devices and methods for treating defects in the tissue of a living being
DE10247689A1 (de) 2002-10-12 2004-04-22 Martin Rahe Implantat in der Harnblase
US6926735B2 (en) 2002-12-23 2005-08-09 Scimed Life Systems, Inc. Multi-lumen vascular grafts having improved self-sealing properties
US7288084B2 (en) * 2003-04-28 2007-10-30 Boston Scientific Scimed, Inc. Drug-loaded medical device
DK1933810T3 (da) 2005-08-11 2013-01-28 Childrens Medical Center Intravesikal lægemiddelafgivelsesindretning og fremgangsmåde
US20080311172A1 (en) * 2007-04-25 2008-12-18 Schapira Jay N Programmed-release, nanostructured biological construct
DK2231254T3 (da) * 2007-12-11 2014-07-21 Massachusetts Inst Technology Implanterbar lægemiddelafgivelsesindretning
CA2733468C (en) 2008-08-09 2017-12-05 Massachusetts Institute Of Technology Implantable drug delivery device and methods of treating male genitourinary and surrounding tissues
FI121000B (fi) * 2008-11-19 2010-06-15 Bayer Schering Pharma Oy Intravaginaalinen antojärjestelmä ja menetelmä sen valmistamiseksi
EA023156B1 (ru) * 2009-06-26 2016-04-29 ТАРИС Биомедикал ЛЛК Устройство для доставки лекарств
US9017312B2 (en) * 2009-09-10 2015-04-28 Taris Biomedical Llc Implantable device for controlled drug delivery
DK2512581T3 (da) * 2009-12-17 2021-03-29 Taris Biomedical Llc Implanterbar indretning med intravesikal tolerance
EP2600800B1 (en) 2010-08-05 2020-09-30 TARIS Biomedical LLC Ureteral stent drug delivery device and kit
HUE051942T2 (hu) 2010-08-05 2021-03-29 Taris Biomedical Llc Implantálható gyógyszerszállító készülékek genitourinális szervekhez
JP5945544B2 (ja) * 2010-10-06 2016-07-05 タリス バイオメディカル エルエルシー 時間選択的に生体吸収可能または崩壊可能な薬剤送達システムおよび方法
WO2012048104A1 (en) * 2010-10-06 2012-04-12 Taris Biomedical, Inc. Implantable drug delivery device with bladden retention feature
BR112013019410A2 (pt) 2011-02-04 2019-09-24 Taris Biomedical Inc dispositivo implantável para liberação controlada de fármaco de solubilidade baixa
EP2734262B1 (en) 2011-07-20 2018-02-28 Patrick F. Kiser Intravaginal rings for drug delivery
WO2013170069A1 (en) 2012-05-09 2013-11-14 Massachusetts Institute Of Technology Medicament, method, and drug delivery device for treatment of ovarian cancer
MX370368B (es) * 2012-05-19 2019-12-11 Taris Biomedical Llc Dispositivo urologico implantable con caracteristica de extraccion mejorada.
PT2968880T (pt) 2013-03-15 2025-07-07 Taris Biomedical Llc Dispositivos de aplicação de fármaco com componente permeável a fármaco
AU2014227914B2 (en) 2013-03-15 2018-05-10 Taris Biomedical Llc Drug delivery devices and methods for drug delivery
KR102503010B1 (ko) 2013-08-19 2023-02-24 타리스 바이오메디컬 엘엘씨 다중 유닛 약물 전달 장치 및 방법
EP3142740B1 (en) 2014-05-12 2020-12-02 TARIS Biomedical LLC Drug delivery devices
JP7425534B2 (ja) 2015-04-23 2024-01-31 タリス バイオメディカル エルエルシー 薬物透過性構成要素を有する薬物送達デバイス及び方法

Also Published As

Publication number Publication date
CN114306899A (zh) 2022-04-12
US20200368508A1 (en) 2020-11-26
JP7005668B2 (ja) 2022-01-21
AU2015279674A1 (en) 2017-01-12
KR102486216B1 (ko) 2023-01-09
EP3517099A1 (en) 2019-07-31
ES2940478T3 (es) 2023-05-08
WO2015200752A8 (en) 2016-08-11
WO2015200752A1 (en) 2015-12-30
AU2022204523A1 (en) 2022-07-21
KR20220061254A (ko) 2022-05-12
AU2020250209B2 (en) 2022-07-14
EP4173615A2 (en) 2023-05-03
KR20170026465A (ko) 2017-03-08
CN106456951A (zh) 2017-02-22
US20200368509A1 (en) 2020-11-26
JP6856380B2 (ja) 2021-04-07
US10737078B2 (en) 2020-08-11
JP2022022292A (ja) 2022-02-03
US11904123B2 (en) 2024-02-20
EP3160442B1 (en) 2019-03-06
EP3517099B1 (en) 2022-12-28
JP2017524421A (ja) 2017-08-31
JP2020110615A (ja) 2020-07-27
AU2015279674B2 (en) 2020-07-23
AU2022204523B2 (en) 2024-05-16
EP4173615A3 (en) 2023-07-19
ES2728504T3 (es) 2019-10-25
DK3160442T3 (da) 2019-06-11
AU2020250209A1 (en) 2020-11-05
KR102391761B1 (ko) 2022-04-27
US12239807B2 (en) 2025-03-04
AU2024204468A1 (en) 2024-07-18
KR20230142816A (ko) 2023-10-11
CN106456951B (zh) 2021-11-05
US20170165460A1 (en) 2017-06-15
EP3160442A1 (en) 2017-05-03

Similar Documents

Publication Publication Date Title
AU2022204523B2 (en) Intravesical drug delivery devices and methods including elastic polymer-drug matrix systems
US12409304B2 (en) Drug delivery devices with drug-permeable component and methods
JP2024028930A (ja) 薬物透過性構成要素を有する薬物送達デバイス及び方法
US20180140748A1 (en) Drug delivery devices and methods
HK40092575A (en) Intravesical drug delivery devices and methods including elastic polymer-drug matrix systems
US20170246437A1 (en) pH-MODULATING DRUG DELIVERY DEVICES AND METHODS
HK40072987A (en) Intravesical drug delivery devices and methods including elastic polymer-drug matrix systems

Legal Events

Date Code Title Description
A107 Divisional application of patent
PA0104 Divisional application for international application

Comment text: Divisional Application for International Patent

Patent event code: PA01041R01D

Patent event date: 20220425

Application number text: 1020177000765

Filing date: 20170110

PA0201 Request for examination
PG1501 Laying open of application
E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20221226

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20230628

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20221226

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I

J201 Request for trial against refusal decision
PJ0201 Trial against decision of rejection

Patent event date: 20230927

Comment text: Request for Trial against Decision on Refusal

Patent event code: PJ02012R01D

Patent event date: 20230628

Comment text: Decision to Refuse Application

Patent event code: PJ02011S01I

Appeal kind category: Appeal against decision to decline refusal

Appeal identifier: 2023101002080

Request date: 20230927

J301 Trial decision

Free format text: TRIAL NUMBER: 2023101002080; TRIAL DECISION FOR APPEAL AGAINST DECISION TO DECLINE REFUSAL REQUESTED 20230927

Effective date: 20250327

PJ1301 Trial decision

Patent event code: PJ13011S01D

Patent event date: 20250327

Comment text: Trial Decision on Objection to Decision on Refusal

Appeal kind category: Appeal against decision to decline refusal

Request date: 20230927

Decision date: 20250327

Appeal identifier: 2023101002080