KR20220046693A - 효소학적 rna 캡핑 방법 - Google Patents

효소학적 rna 캡핑 방법 Download PDF

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KR20220046693A
KR20220046693A KR1020227009727A KR20227009727A KR20220046693A KR 20220046693 A KR20220046693 A KR 20220046693A KR 1020227009727 A KR1020227009727 A KR 1020227009727A KR 20227009727 A KR20227009727 A KR 20227009727A KR 20220046693 A KR20220046693 A KR 20220046693A
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ile
leu
lys
rna
asn
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Korean (ko)
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지. 브레트 롭
시우-홍 찬
비조이타 로이
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뉴 잉글랜드 바이오랩스, 인크
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Priority claimed from PCT/US2020/047533 external-priority patent/WO2021041267A1/en
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    • C12N9/10—Transferases (2.)
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    • C12N9/10—Transferases (2.)
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    • C12N9/1077—Pentosyltransferases (2.4.2)
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    • C12P19/28—N-glycosides
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    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • C12Y201/01—Methyltransferases (2.1.1)
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    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/02—Pentosyltransferases (2.4.2)
    • C12Y204/02003—Uridine phosphorylase (2.4.2.3)
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    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07—Nucleotidyltransferases (2.7.7)
    • C12Y207/07045—Guanosine-triphosphate guanylyltransferase (2.7.7.45)

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  • General Chemical & Material Sciences (AREA)
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  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1020227009727A 2019-08-23 2020-08-21 효소학적 rna 캡핑 방법 Pending KR20220046693A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962890821P 2019-08-23 2019-08-23
US62/890,821 2019-08-23
PCT/US2020/047533 WO2021041267A1 (en) 2019-08-23 2020-08-21 Enzymatic rna capping method
PCT/US2020/047521 WO2021041260A1 (en) 2019-08-23 2020-08-21 Enzymatic rna capping method
USPCT/US2020/047521 2020-08-21

Publications (1)

Publication Number Publication Date
KR20220046693A true KR20220046693A (ko) 2022-04-14

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US (5) US12479880B2 (https=)
JP (2) JP7749539B2 (https=)
KR (1) KR20220046693A (https=)
AU (1) AU2020336278A1 (https=)
BR (1) BR112022003517A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230148714A (ko) 2022-04-18 2023-10-25 에스케이바이오사이언스(주) 면역원성 조성물 및 이의 제조방법

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7749539B2 (ja) * 2019-08-23 2025-10-06 ニユー・イングランド・バイオレイブス・インコーポレイテツド 酵素的ｒｎａキャッピング法
WO2025164636A1 (ja) * 2024-01-30 2025-08-07 タカラバイオ株式会社 ファウストウイルスｓ１７株由来のｒｎａキャッピング酵素
WO2025263589A1 (ja) * 2024-06-20 2025-12-26 ヤマサ醤油株式会社 Ｒｎａの５'末端から１番目及び２番目のヌクレオチドにおけるリボースの水酸基をメチル化するためのメチル基転移酵素、メチル化方法、メチル基転移酵素の使用、及びキット

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EP2010659B1 (en) 2006-04-14 2014-06-18 CellScript, Inc. Kits and methods for generating 5' capped RNA
EP2377938A1 (en) 2010-04-16 2011-10-19 Eukarys Capping-prone RNA polymerase enzymes and their applications
AU2012236099A1 (en) 2011-03-31 2013-10-03 Moderna Therapeutics, Inc. Delivery and formulation of engineered nucleic acids
WO2014028429A2 (en) 2012-08-14 2014-02-20 Moderna Therapeutics, Inc. Enzymes and polymerases for the synthesis of rna
KR101422936B1 (ko) 2012-11-30 2014-07-23 삼성전기주식회사 모터 구동 제어 장치, 모터 구동 제어 방법 및 그를 이용한 모터
ES3032935T3 (en) 2013-10-22 2025-07-29 Translate Bio Inc Lipid formulations for delivery of messenger rna
EP3077406B1 (en) 2013-12-05 2019-07-10 New England Biolabs, Inc. Compositions and methods for capping rna
US11479766B2 (en) 2013-12-05 2022-10-25 New England Biolabs, Inc. Methods for labeling a population of RNA molecules
US10428368B2 (en) * 2013-12-05 2019-10-01 New England Biolabs, Inc. Methods for enriching for a population of RNA molecules
BR112016030852A2 (pt) 2014-07-02 2018-01-16 Shire Human Genetic Therapies encapsulação de rna mensageiro
EP3303575B1 (en) * 2015-05-29 2022-03-16 CureVac AG Method for adding cap structures to rna using immobilized enzymes
CN116144626A (zh) 2016-01-13 2023-05-23 新英格兰生物实验室公司 T7 rna聚合酶的热稳定变体
US10034951B1 (en) 2017-06-21 2018-07-31 New England Biolabs, Inc. Use of thermostable RNA polymerases to produce RNAs having reduced immunogenicity
CN111164207A (zh) * 2017-07-27 2020-05-15 优卡瑞斯 新型嵌合酶及其应用
US12398173B2 (en) * 2019-08-23 2025-08-26 New England Biolabs, Inc. Enzymatic RNA capping method
JP7749539B2 (ja) * 2019-08-23 2025-10-06 ニユー・イングランド・バイオレイブス・インコーポレイテツド 酵素的ｒｎａキャッピング法
US11788074B2 (en) 2020-06-23 2023-10-17 New England Biolabs, Inc. Vaccinia capping enzyme compositions and methods

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230148714A (ko) 2022-04-18 2023-10-25 에스케이바이오사이언스(주) 면역원성 조성물 및 이의 제조방법

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JP2026001059A (ja) 2026-01-06
JP2022544712A (ja) 2022-10-20
CA3147797A1 (en) 2021-03-04
US20250388618A1 (en) 2025-12-25
JP7749539B2 (ja) 2025-10-06
US12479880B2 (en) 2025-11-25
US20260062438A1 (en) 2026-03-05
AU2020336278A1 (en) 2022-04-07
US20240383939A1 (en) 2024-11-21
US20260062439A1 (en) 2026-03-05
US20260015379A1 (en) 2026-01-15
BR112022003517A2 (pt) 2022-07-19

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