KR20220027941A - 리포솜 아나마이신의 재구성 방법 - Google Patents

리포솜 아나마이신의 재구성 방법 Download PDF

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Publication number
KR20220027941A
KR20220027941A KR1020227000486A KR20227000486A KR20220027941A KR 20220027941 A KR20220027941 A KR 20220027941A KR 1020227000486 A KR1020227000486 A KR 1020227000486A KR 20227000486 A KR20227000486 A KR 20227000486A KR 20220027941 A KR20220027941 A KR 20220027941A
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South Korea
Prior art keywords
anamycin
liposomal
bag
vial
physiological saline
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Pending
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KR1020227000486A
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English (en)
Korean (ko)
Inventor
도날드 픽커
발데마르 프리에베
Original Assignee
더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템
몰컬린 바이오테크 인코포레이티드
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Application filed by 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템, 몰컬린 바이오테크 인코포레이티드 filed Critical 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템
Publication of KR20220027941A publication Critical patent/KR20220027941A/ko
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
KR1020227000486A 2019-06-28 2020-06-25 리포솜 아나마이신의 재구성 방법 Pending KR20220027941A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962868190P 2019-06-28 2019-06-28
US62/868,190 2019-06-28
PCT/US2020/039621 WO2020264161A1 (en) 2019-06-28 2020-06-25 Method of reconstituting liposomal annamycin

Publications (1)

Publication Number Publication Date
KR20220027941A true KR20220027941A (ko) 2022-03-08

Family

ID=74061076

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020227000486A Pending KR20220027941A (ko) 2019-06-28 2020-06-25 리포솜 아나마이신의 재구성 방법

Country Status (15)

Country Link
US (2) US12257262B2 (https=)
EP (1) EP3990041B1 (https=)
JP (1) JP7830131B2 (https=)
KR (1) KR20220027941A (https=)
CN (2) CN114728101B (https=)
AU (2) AU2020302784A1 (https=)
BR (1) BR112021026480A2 (https=)
CA (1) CA3144443A1 (https=)
ES (1) ES3049663T3 (https=)
IL (1) IL289433B1 (https=)
MX (1) MX2021015667A (https=)
PL (1) PL3990041T3 (https=)
SG (1) SG11202113005SA (https=)
TW (2) TW202500161A (https=)
WO (1) WO2020264161A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES3049663T3 (en) 2019-06-28 2025-12-17 Univ Texas Method of reconstituting liposomal annamycin
KR20220027969A (ko) 2019-06-28 2022-03-08 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 프리리포솜 아나마이신 동결건조물의 제조
KR20220103992A (ko) * 2019-11-21 2022-07-25 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 리포솜 아나마이신에 의한 폐 표적화 항암 요법

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4927571A (en) * 1987-05-18 1990-05-22 Liposome Technology, Inc. Preparation of injectable doxorubicin/liposome suspension
US4863739A (en) 1987-05-19 1989-09-05 Board Of Regents, The University Of Texas System Liposome compositions of anthracycline derivatives
IS1685B (is) * 1990-12-11 1998-02-24 Bracco International B.V. Aðferð við að búa til fitukúlur (liposomes) sem eru gæddar auknum hæfileika til að draga í sig og halda í sér aðskotaefnum
US5902604A (en) * 1995-06-06 1999-05-11 Board Of Regents, The University Of Texas System Submicron liposome suspensions obtained from preliposome lyophilizates
WO2001032145A1 (en) * 1999-10-29 2001-05-10 Board Of Regents, The University Of Texas System Method of cancer treatment
EP2314285B2 (en) * 2003-02-14 2019-09-18 Children's Hospital & Research Center at Oakland Lipophilic drug delivery vehicle and methods of use thereof
PL2544537T3 (pl) * 2010-03-10 2017-10-31 Cempra Pharmaceuticals Inc Pozajelitowe preparaty antybiotyków makrolidowych
WO2013055874A2 (en) * 2011-10-14 2013-04-18 Genentech, Inc. Uses for and article of manufacture including her2 dimerization inhibitor pertuzumab
EP3572071A1 (en) * 2011-10-21 2019-11-27 Jazz Pharmaceuticals Research LLC Lyophilized liposomes
US8926994B2 (en) 2011-12-07 2015-01-06 The Methodist Hospital Research Institute Mesoporous silicon particles for the presentation of tumor antigens and adjuvant for anti-cancer immunity
ES2771926T3 (es) 2014-09-13 2020-07-07 Novartis Ag Terapias de combinación
AU2015327868A1 (en) 2014-10-03 2017-04-20 Novartis Ag Combination therapies
CN107569508A (zh) * 2016-07-05 2018-01-12 江苏竞诺择生物医药科技有限公司 一种治疗造血系统增殖性疾病的药用组合物
WO2018048752A1 (en) 2016-09-09 2018-03-15 Irisys, Inc. Lipsomal anticancer compositions
WO2019023873A1 (zh) * 2017-07-31 2019-02-07 江苏竞诺择生物医药科技有限公司 一种用于治疗造血系统增殖性疾病的纳米脂质微粒组合物及药用组合物
MA53565A (fr) 2018-09-04 2021-07-14 Minerva Neurosciences Inc Procédés d'utilisation d'un composé phénoxypropylamine pour le traitement de la douleur
ES3049663T3 (en) 2019-06-28 2025-12-17 Univ Texas Method of reconstituting liposomal annamycin
KR20220027969A (ko) 2019-06-28 2022-03-08 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 프리리포솜 아나마이신 동결건조물의 제조
KR20220103992A (ko) 2019-11-21 2022-07-25 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 리포솜 아나마이신에 의한 폐 표적화 항암 요법

Also Published As

Publication number Publication date
EP3990041A1 (en) 2022-05-04
TW202500161A (zh) 2025-01-01
EP3990041B1 (en) 2025-08-06
CN114728101B (zh) 2023-07-14
CN114728101A (zh) 2022-07-08
PL3990041T3 (pl) 2026-02-23
US12257262B2 (en) 2025-03-25
AU2020302784A1 (en) 2022-01-20
IL289433A (en) 2022-02-01
US11980634B2 (en) 2024-05-14
JP2023523872A (ja) 2023-06-08
CA3144443A1 (en) 2020-12-30
WO2020264161A1 (en) 2020-12-30
JP7830131B2 (ja) 2026-03-16
SG11202113005SA (en) 2021-12-30
TW202114704A (zh) 2021-04-16
BR112021026480A2 (pt) 2022-02-08
EP3990041A4 (en) 2023-07-12
US20240024345A1 (en) 2024-01-25
MX2021015667A (es) 2022-04-18
CN116785242A (zh) 2023-09-22
US20220105116A1 (en) 2022-04-07
TWI857086B (zh) 2024-10-01
IL289433B1 (en) 2026-01-01
AU2024203593B2 (en) 2025-08-14
ES3049663T3 (en) 2025-12-17
AU2024203593A1 (en) 2024-07-11

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