KR20220022828A - 조합 치료 - Google Patents
조합 치료 Download PDFInfo
- Publication number
- KR20220022828A KR20220022828A KR1020200150157A KR20200150157A KR20220022828A KR 20220022828 A KR20220022828 A KR 20220022828A KR 1020200150157 A KR1020200150157 A KR 1020200150157A KR 20200150157 A KR20200150157 A KR 20200150157A KR 20220022828 A KR20220022828 A KR 20220022828A
- Authority
- KR
- South Korea
- Prior art keywords
- inhibitor
- protein
- recombinant
- apyrase
- patient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- C12Y306/00—Hydrolases acting on acid anhydrides (3.6)
- C12Y306/01—Hydrolases acting on acid anhydrides (3.6) in phosphorus-containing anhydrides (3.6.1)
- C12Y306/01005—Apyrase (3.6.1.5), i.e. ATP diphosphohydrolase
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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| WO2024089196A1 (en) | 2022-10-28 | 2024-05-02 | Astrazeneca Ab | Recombinant apyrase protein for use in the treatment of an ischemic event at a dose of 40-240 mg |
| WO2025104274A1 (en) * | 2023-11-16 | 2025-05-22 | Hyloris Developments Sa | Ticagrelor iv for use in the prevention of thromboembolic events |
| WO2025104277A1 (en) * | 2023-11-16 | 2025-05-22 | Hyloris Developments Sa | Ticagrelor iv for use in the treatment, reduction or prevention of an ischemic event in a patient undergoing a percutaneous coronary intervention (pci) |
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| US7247300B1 (en) | 2002-11-07 | 2007-07-24 | Apt Therapeutics, Inc. | Therapeutic use of soluble CD39L3 |
| EP1733045A4 (en) | 2004-02-27 | 2008-08-13 | Apt Therapeutics Inc | DESIGN AND THERAPEUTIC USE OF ADPASE-ENHANCED APYRASES |
| TWI482772B (zh) | 2006-08-21 | 2015-05-01 | Astrazeneca Ab | 適合口服且包含三唑并[4,5-d]嘧啶衍生物之組合物 |
| WO2011088231A1 (en) * | 2010-01-13 | 2011-07-21 | Apt Therapeutics, Inc. | Apyrase therapy for bleeding conditions |
| AU2011205248A1 (en) | 2010-01-13 | 2012-08-02 | Apt Therapeutics, Inc. | Therapeutic apyrase constructs, apyrase agents, and production methods |
| CN107595789B (zh) | 2016-04-21 | 2021-01-15 | 阿斯利康(瑞典)有限公司 | 口腔崩解片 |
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| JP2022035920A (ja) | 2022-03-04 |
| TW202207937A (zh) | 2022-03-01 |
| AU2020267165B2 (en) | 2024-01-04 |
| CN116096874A (zh) | 2023-05-09 |
| AU2020267165A1 (en) | 2022-03-10 |
| US20220073888A1 (en) | 2022-03-10 |
| JP7657041B2 (ja) | 2025-04-04 |
| CA3098818A1 (en) | 2022-02-19 |
| EP4199955A1 (en) | 2023-06-28 |
| US20240026318A1 (en) | 2024-01-25 |
| WO2022038191A1 (en) | 2022-02-24 |
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