KR20210136044A - 4-하이드록시메틸푸르푸랄 및 그 유도체의 생체 내 합성 방법 - Google Patents
4-하이드록시메틸푸르푸랄 및 그 유도체의 생체 내 합성 방법 Download PDFInfo
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- KR20210136044A KR20210136044A KR1020217030955A KR20217030955A KR20210136044A KR 20210136044 A KR20210136044 A KR 20210136044A KR 1020217030955 A KR1020217030955 A KR 1020217030955A KR 20217030955 A KR20217030955 A KR 20217030955A KR 20210136044 A KR20210136044 A KR 20210136044A
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- formylfuran
- dehydrogenase
- oxidase
- carboxylate
- clostridium
- Prior art date
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- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0065—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
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- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
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- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/03—Oxidoreductases acting on the CH-OH group of donors (1.1) with a oxygen as acceptor (1.1.3)
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- C12Y—ENZYMES
- C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
- C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
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- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/03—Phosphoric monoester hydrolases (3.1.3)
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- C12Y—ENZYMES
- C12Y402/00—Carbon-oxygen lyases (4.2)
- C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01001—Alcohol dehydrogenase (1.1.1.1)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
- C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
- C12Y102/01003—Aldehyde dehydrogenase (NAD+) (1.2.1.3)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
- C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
- C12Y102/01004—Aldehyde dehydrogenase (NADP+) (1.2.1.4)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
- C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
- C12Y102/01005—Aldehyde dehydrogenase [NAD(P)+] (1.2.1.5)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962812904P | 2019-03-01 | 2019-03-01 | |
US62/812,904 | 2019-03-01 | ||
PCT/BR2020/050064 WO2020176958A1 (fr) | 2019-03-01 | 2020-03-02 | Procédé de synthèse in vivo de 4-hydroxyméthylfurfural et de ses dérivés |
Publications (1)
Publication Number | Publication Date |
---|---|
KR20210136044A true KR20210136044A (ko) | 2021-11-16 |
Family
ID=70189623
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020217030955A KR20210136044A (ko) | 2019-03-01 | 2020-03-02 | 4-하이드록시메틸푸르푸랄 및 그 유도체의 생체 내 합성 방법 |
Country Status (9)
Country | Link |
---|---|
US (5) | US11339414B2 (fr) |
EP (1) | EP3921435A1 (fr) |
JP (1) | JP2022523540A (fr) |
KR (1) | KR20210136044A (fr) |
CN (1) | CN113748211A (fr) |
BR (1) | BR112021016818A2 (fr) |
CA (1) | CA3132051A1 (fr) |
MX (1) | MX2021010457A (fr) |
WO (1) | WO2020176958A1 (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
MX2022014991A (es) * | 2020-05-29 | 2023-04-19 | Braskem Sa | Produccion y uso de plastificadores basados en 2,4-isomero de diesteres de acido furandicarboxilico. |
WO2022047559A1 (fr) | 2020-09-01 | 2022-03-10 | Braskem S.A. | Production par fermentation anaérobie de furandiméthanol et production enzymatique d'acide furandicarboxylique |
US11692210B2 (en) | 2020-09-01 | 2023-07-04 | Braskem S.A. | Anaerobic fermentative production of furandicarboxylic acid |
EP4284855A1 (fr) | 2021-01-29 | 2023-12-06 | Braskem, S.A. | Co-polyesters de 2,4-fdca à plus grande commande de cristallisation |
US20230002363A1 (en) | 2021-06-16 | 2023-01-05 | Braskem S.A. | Furanic diglycidyl ethers and esters and use thereof |
CN113913448B (zh) * | 2021-07-23 | 2023-10-20 | 中国人民解放军军事科学院军事医学研究院 | 一种提高甲基营养菌吡咯喹啉醌产量的方法及应用 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6740506B2 (en) | 1995-12-07 | 2004-05-25 | Diversa Corporation | End selection in directed evolution |
US6033861A (en) | 1997-11-19 | 2000-03-07 | Incyte Genetics, Inc. | Methods for obtaining nucleic acid containing a mutation |
US8460726B2 (en) | 2006-12-18 | 2013-06-11 | Advanced Bionutrition Corporation | Dry food product containing live probiotic |
EP2495239B1 (fr) | 2009-07-09 | 2016-11-16 | University of Science and Technology of China | Procédé pour la préparation de 4-hydroxyméthylfurfural |
NL2006359C2 (en) * | 2011-03-08 | 2012-04-24 | Bird Engineering B V | Genetically modified cell and process for use of said cell. |
EP4234696A3 (fr) | 2012-12-12 | 2023-09-06 | The Broad Institute Inc. | Systèmes de composants crispr-cas, procédés et compositions pour la manipulation de séquence |
US9937207B2 (en) | 2013-03-21 | 2018-04-10 | Sangamo Therapeutics, Inc. | Targeted disruption of T cell receptor genes using talens |
NL2011027C2 (en) * | 2013-06-24 | 2014-12-29 | Univ Delft Tech | Process for the preparation of 2,5-furandicarboxylic acid. |
DK3259349T3 (da) * | 2015-02-17 | 2020-08-10 | Purac Biochem Bv | Dehydrogenase-katalyseret fremstilling af FDCA |
EP3378931A1 (fr) * | 2017-03-21 | 2018-09-26 | Purac Biochem B.V. | Cellules hôtes déficientes en monooxygenase à décarboxylation de fdca pour la production de fdca |
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2020
- 2020-03-02 JP JP2021551764A patent/JP2022523540A/ja active Pending
- 2020-03-02 MX MX2021010457A patent/MX2021010457A/es unknown
- 2020-03-02 WO PCT/BR2020/050064 patent/WO2020176958A1/fr unknown
- 2020-03-02 EP EP20717077.0A patent/EP3921435A1/fr active Pending
- 2020-03-02 CN CN202080032050.1A patent/CN113748211A/zh active Pending
- 2020-03-02 KR KR1020217030955A patent/KR20210136044A/ko unknown
- 2020-03-02 BR BR112021016818A patent/BR112021016818A2/pt unknown
- 2020-03-02 CA CA3132051A patent/CA3132051A1/fr active Pending
- 2020-03-02 US US16/806,728 patent/US11339414B2/en active Active
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2021
- 2021-02-01 US US17/163,838 patent/US11566269B2/en active Active
- 2021-03-31 US US17/219,792 patent/US11566270B2/en active Active
- 2021-12-08 US US17/545,616 patent/US20220090153A1/en active Pending
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2022
- 2022-05-20 US US17/750,293 patent/US20220298535A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US20210222217A1 (en) | 2021-07-22 |
CA3132051A1 (fr) | 2020-09-10 |
BR112021016818A2 (pt) | 2021-11-16 |
US11566269B2 (en) | 2023-01-31 |
US20210238639A1 (en) | 2021-08-05 |
US20220298535A1 (en) | 2022-09-22 |
MX2021010457A (es) | 2021-12-10 |
US11566270B2 (en) | 2023-01-31 |
US20200277639A1 (en) | 2020-09-03 |
US20220090153A1 (en) | 2022-03-24 |
EP3921435A1 (fr) | 2021-12-15 |
US11339414B2 (en) | 2022-05-24 |
WO2020176958A1 (fr) | 2020-09-10 |
CN113748211A (zh) | 2021-12-03 |
JP2022523540A (ja) | 2022-04-25 |
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