KR20210066568A - Composition of anti bacterial containing Zophobas morio oil - Google Patents

Abstract

The present invention relates to an antibacterial composition including super mealworm larva oil and soap including the same. The soap of the present invention provides antibacterial soap that is harmless to the skin during washing by containing super mealworm oil, is eco-friendly, and has excellent antibacterial action, thereby alleviating inflammatory skin diseases and skin troubles caused by various bacteria.

Description

Antibacterial composition containing American mealworm oil {Composition of anti bacterial containing Zophobas morio oil}

The present invention relates to an antibacterial composition comprising American mealworm oil, and a soap comprising the same.

In recent years, the interest and demand for health and skin beauty is increasing regardless of gender and age, and the most basic product used for skin care is soap.

As a normal soap maximizes the function of its cleansing power, it removes more than necessary sebum components accumulated in the skin epithelial tissue during the washing process, for example, in sensitive skin and dry skin, by leaching essential oils and moisture components excessively, the skin becomes rough as much as possible. There is a problem of fading and drying out. In addition, there is a problem that causes various side effects such as irritation and rash on the skin of people with sensitive skin or dry skin when using the soap.

In order to solve the problems of conventional soaps prepared with such chemical components, soaps containing natural ingredients have been recently developed. Among them, soaps with antibacterial function have been developed for the prevention and treatment of inflammatory skin diseases, such as atopic dermatitis, acne, and psoriasis, which are caused by direct contact with external stimuli, various pathogens, or strong influence from the body. have.

The American mealworm ( Zophobas morio , Z. morio ) is an insect belonging to the Insectoptera Coleoptera family Melluridae and is mostly used as feed, food and medicine, and environmental insects, and grows up to 5 cm tall. Z. morio has been called a super worm or king worm because it has the largest body size in Korea compared to mealworm, which is the larva of brown mealworm most used for animal feed, and small animals (arthropods). It is widely used as a major protein supply source for animals, birds, amphibians, and small mammals). In Korea, research and development are in progress on natural cosmetics that contain brown mealworm larvae, and in 2017, natural whitening cosmetics using brown mealworm larvae were developed.

Republic of Korea Patent Registration No. 10-0971269

One object of the present invention is to provide an antibacterial composition comprising the oil of American mealworm ( Zophobas morio ) larvae.

Another object of the present invention is to provide an antibacterial cosmetic composition comprising the oil of the American mealworm ( Zophobas morio ) larvae.

Another object of the present invention is to provide an antibacterial soap containing the oil of the American mealworm ( Zophobas morio ) larvae.

In order to solve the above object, the present invention provides an antibacterial composition comprising the oil of the American mealworm (Zophobas morio) larvae.

The antibacterial composition of the present invention contains the oil of the larvae of the American mealworm (Zophobas morio).

In the present invention, "American mealworm ( Zophobas morio )" is an insect belonging to the family Insectaceae Coleoptera.

The "oil of the larvae of the American worm" of the present invention is an oil component extracted from the larvae (larvae) of the larvae of the larvae of the larvae of the American larvae, and may specifically be an n-hexane extract.

In an Example of the present invention, American mealworm larvae hatched from eggs 3 or 4 months old were freeze-dried, extracted and concentrated at 25° C. for 4 hours to prepare Melancholy oil. It was confirmed that the number of months of larvae did not significantly affect the yield of oil. Next, as a result of analyzing the antibacterial effect on Staphylococcus aureus , Pseudomonas aeruginosa , and Propionibacterium acnes strains, the oils extracted from 3-month-old and 4-month-old larvae were all Staphylococcus ( Staphylococcus). aureus ), Pseudomonas aeruginosa ), and Propionibacterium acnes were confirmed to have antibacterial activity, and it was confirmed that the oil extracted from 3-month-old larvae had better antibacterial activity, specifically in 3-month-old larvae. It was confirmed that the extracted oil had the best antibacterial activity against Staphylococcus aureus.

The antibacterial composition of the present invention has an antibacterial effect against at least one strain selected from the group consisting of Staphylococcus aureus , Pseudomonas aeruginosa , and Propionibacterium acnes.

It was confirmed that the antibacterial effect of the oil extracted from the 3-month-old larva was superior to the oil extracted from the 4-month-old larva in the above-described embodiment, and the American mealworm larvae may be larvae 2.5 to 3.5 months after hatching from eggs, specifically It may be a larva 3 months after hatching from an egg.

In the present invention, the antibacterial composition is one selected from the group consisting of cosmetics, skin cleaners, hair cleaners, vaginal cleaners, bathroom cleaners, mouthwashes, kitchen cleaners, cosmetic preservatives, food preservatives, pharmaceutical preservatives, food additives and feed additives. can be used for the purpose of

In another aspect of the present invention, there is provided an antibacterial cosmetic composition comprising the oil of the American mealworm ( Zophobas morio ) larvae.

The antibacterial cosmetic composition of the present invention contains the oil of the American mealworm ( Zophobas morio ) larvae.

In the above-described embodiment, the oil of the larvae of the American larvae Staphylococcus aureus ), Pseudomonas aeruginosa ) and Propionibacterium acnes It was confirmed that it has an antibacterial effect against, the cosmetic of the present invention The composition has an antibacterial effect, specifically Staphylococcus aureus ), Pseudomonas aeruginosa ) and Propionibacterium acnes . It may have an antibacterial effect against one or more strains selected from the group consisting of .

The antibacterial cosmetic composition of the present invention may contain 0.001 to 100% by weight of the larvae of American larvae based on the total weight of the composition, and specifically 0.01 to 50% by weight of the oil of larvae of the larvae of American larvae. And, more specifically, it may include 0.1 to 5% by weight of oil of the larvae of the American mongoose larvae, but is not limited thereto.

In addition, the cosmetic composition of the present invention may include, without limitation, commonly acceptable ingredients in addition to the above active ingredients, for example, conventional adjuvants such as antioxidants, stabilizers, solubilizers, vitamins, pigments and fragrances, and carriers. can do.

The cosmetic composition according to the present invention includes solutions, external ointments, creams, foams, nourishing lotions, softening lotions, packs, makeup bases, essences, liquid detergents, bathing agents, sunscreen creams, sun oils, suspensions, emulsions, pastes, gels, It can be prepared in one or more formulations selected from the group consisting of lotions, powders, soaps, surfactant-containing cleansing, oils, powder foundations, emulsion foundations, wax foundations, patches and sprays.

In addition, the cosmetic composition of the present invention may further include one or more cosmetically acceptable carriers to be formulated in general skin cosmetics, and conventional ingredients include, for example, oil, water, surfactant, humectant, lower alcohol, A thickener, a chelating agent, a colorant, a preservative, a fragrance, etc. may be appropriately mixed, but is not limited thereto.

The cosmetically acceptable carrier included in the cosmetic composition of the present invention varies depending on the formulation.

When the formulation of the present invention is an ointment, paste, cream or gel, animal oil, vegetable oil, wax, paraffin, starch, tracanth, cellulose derivative, polyethylene glycol, silicone, bentonite, silica, talc, zinc oxide or Mixtures thereof may be used.

When the formulation of the present invention is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate, polyamide powder or a mixture thereof may be used as a carrier component, and in particular, in the case of a spray, additional chloro propellants such as fluorohydrocarbons, propane/butane or dimethyl ether.

When the formulation of the present invention is a solution or emulsion, a solvent, solubilizer or emulsifier is used as a carrier component, such as water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene glycol, 1,3-butylglycol oil may be used, and in particular, cottonseed oil, peanut oil, corn germ oil, olive oil, castor oil and sesame oil, glycerol fatty ester, fatty acid ester of polyethylene glycol or sorbitan may be used. have.

When the formulation of the present invention is a suspension, as a carrier component a liquid diluent such as water, ethanol or propylene glycol, a suspending agent such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol esters and polyoxyethylene sorbitan esters; Crystalline cellulose, aluminum metahydroxide, bentonite, agar or tracanth may be used.

When the formulation of the present invention is soap, alkali metal salts of fatty acids, fatty acid hemiester salts, fatty acid protein hydrolyzates, isethionate, lanolin derivatives, aliphatic alcohols, vegetable oils, glycerol, sugar, etc. may be used as carrier components. can

When the formulation of the present invention is a surfactant-containing cleansing agent, aliphatic alcohol sulfate, aliphatic alcohol ether sulfate, sulfosuccinic acid monoester, isethionate, imidazolinium derivative, methyltaurate, sarcositate, fatty acid amide as carrier components Ether sulfates, alkylamidobetaines, fatty alcohols, fatty acid glycerides, fatty acid diethanolamides, vegetable oils, lanolin derivatives or ethoxylated glycerol fatty acid esters can be used.

In another aspect of the present invention, there is provided an antibacterial soap containing the oil of the American mealworm ( Zophobas morio ) larvae.

The antibacterial soap of the present invention contains the oil of the American mealworm ( Zophobas morio ) larvae.

In the above-described embodiment, the oil of the larvae of the American larvae Staphylococcus aureus ), Pseudomonas aeruginosa ) and Propionibacterium acnes It was confirmed that it has an antibacterial effect against, the soap of the present invention has an antibacterial effect, specifically Staphylococcus aureus ), Pseudomonas aeruginosa ) and Propionibacterium acnes It may have an antibacterial effect against one or more strains selected from the group consisting of.

In the present invention, the description of the oil of the American mealworm larvae is the same as described above.

In an embodiment of the present invention, 36 to 57% by weight of a sodium salt of palm oil or palm oil fatty acid, 4 to 8% by weight of sodium lauryl sulfate, 25 to 30% by weight of glycerin, 5 to 9% by weight of sucrose, 0.5 to 1% by weight of shea butter %, 0.5 to 1% by weight of camellia oil, 0.1% by weight of titanium dioxide, 0.1 to 0.2% by weight of Centella asiatica extract and 0.6% by weight of vitamin E and other functional additives (see Tables 2 to 4) are mixed and 1% by weight of American king Meal meal oil was mixed to make soap.

In the example of the present invention, it was confirmed that when 1 wt% was added, there was no insect peculiar smell and the soap material was mixed well. Therefore, the soap of the present invention may contain 0.1 to 5% by weight of the total composition, specifically, 1% by weight of the oil of the American mealworm larvae.

In addition, the soap contains 36 to 57% by weight of a sodium salt of palm oil or palm oil fatty acid, 4 to 8% by weight of sodium lauryl sulfate, 25 to 30% by weight of glycerin, 5 to 9% by weight of sucrose, 0.5 to 1% by weight of shea butter , 0.5 to 1% by weight of camellia oil, 0.1% by weight of titanium dioxide, 0.1 to 0.2% by weight of Centella asiatica extract and 0.6% by weight of vitamin E may be further included.

The present invention relates to an antibacterial composition comprising Mechloe larvae oil and a soap comprising the same. The soap of the present invention contains Mechworm oil, so it is harmless to the skin when washing, and is eco-friendly and has excellent antibacterial action to reduce inflammation. It provides antibacterial soap that improves skin troubles caused by various bacteria, including skin diseases.

1 is an extraction process of American mealworm oil.
2 is a manufacturing process of American mealworm oil.

Hereinafter, the configuration and effects of the present invention will be described in more detail through examples. These examples are only for illustrating the present invention, and the scope of the present invention is not limited by these examples.

Example 1: Extraction of Mealworm Oil

The larvae of 3 months and 4 months after hatching from the American king mealworm were used. Larvae were used after quenching and freeze-drying. After adding n-hexane solvent to the freeze-dried larvae, extraction was performed at 25° C. for 4 hours, after which the extract was concentrated, and American mealworm oil and skim larvae were separated.

Example 2: American Mealworm Oil Recovery Rate and Antibacterial Activity Analysis

As a result of analyzing the recovery rate of the extracted oil, it was confirmed that there was no significant difference in the extraction rate, with 30.2% for 3-month-old larvae and 30.54% for 4-month-old larvae.

Next, Staphylococcus aureus , Pseudomonas aeruginosa , and Propionibacterium acne of the 3 month and 4 month larvae extract oil were measured for growth inhibition and the antibacterial activity was analyzed.

As a result of the analysis, Mealworm oil extracted from 3-month-old larvae showed greater antibacterial activity against Staphylococcus aureus , Pseudomonas aeruginosa , and Propionibacterium acne than Mealworm oil extracted from 4-month-old larvae. It was confirmed that the superiority was confirmed, and specifically, Staphylococcus aureus had the largest difference in the growth inhibition ring size, and Staphylococcus aureus antibacterial activity of the 3-month larval extract oil was confirmed to be the best (Table 1 ).

division Oil recovery rate
(%) Growth inhibition ring (mm) Staphylococcus aureus Pseudomonas aeruginosa Propionibacterium acnes 3 month larva 30.2 15.60 13.03 9.84 4 month larva 30.54 11.17 11.91 9.34

Example 3: Manufacture of American Mealworm Oil-Added Soap and Evaluation of Quality Characteristics

With the composition shown in Tables 2 to 4, functional soaps for acne trouble (Table 2), whitening elasticity (Table 3), and moisturizing and soothing (Table 4) were prepared.

Among the compositions of Tables 2 to 4, materials except for American mealworm oil were blended and melted. Thereafter, American mealworm oil was added at 40° C., poured into a mold, and molded and coagulated to prepare each functional soap ( FIG. 2 ).

Specifically, each soap contains palm oil, 36 to 57% by weight of a sodium salt of palm oil fatty acid, 4 to 8% by weight of sodium lauryl sulfate, 25 to 30% by weight of glycerin, 5 to 9% by weight of sucrose, 0.5 to 1% by weight of shea butter , 0.5 to 1% by weight of camellia oil, 0.1% by weight of titanium dioxide, 0.1 to 0.2% by weight of Centella asiatica extract, 0.6% by weight of vitamin E and 1% by weight of American mealworm oil, acne trouble, whitening elasticity, moisturizing and soothing Functional soap was prepared by adding different additives (essential oil, etc.) according to the

ingredient acne trouble Sodium salt of palm oil and palm oil fatty acids 36 to 57 Sodium Lauryl Sulfate 4 to 8 glycerin 25 to 30 sucrose 5 to 9 Distilled water 15 to 20 shea butter 0.5 to 1.0 camellia oil 0.5 to 1.0 titanium dioxide 0.1 Centella asiatica extract 0.1 to 0.2 Eoseongcho powder 0.6 American Mealworm Oil One vitamin e 0.6 honey extract 0.1 carrot extract 0.1 lemon essential oil 0.6 May Chang essential oil 0.25 tea tree essential oil 0.25

ingredient whitening elasticity Sodium salt of palm oil, palm oil fatty acid 36 to 57 Sodium Lauryl Sulfate 4 to 8 glycerin 25 to 30 sucrose 5 to 9 Distilled water 15 to 20 shea butter 0.5 to 1.0 camellia oil 0.5 to 1.0 titanium dioxide 0.1 Centella asiatica extract 0.1 to 0.2 pearl powder 0.55 American Mealworm Oil One vitamin e 0.6 cucumber extract 0.2 Licorice Extract 0.2 Apricot Seed Extract 0.04 lemon essential oil 0.6 grapefruit essential oil 0.3 Soowit Orange Essential Oil 0.45

ingredient moisturizing and soothing Sodium salt of palm oil, palm oil fatty acid 36 to 57 Sodium Lauryl Sulfate 4 to 8 glycerin 25 to 30 sucrose 5 to 9 Distilled water 15 to 20 shea butter 0.5 to 1.0 camellia oil 0.5 to 1.0 titanium dioxide 0.1 Centella asiatica extract 0.1 to 0.2 Cypress Powder 0.55 American Mealworm Oil One vitamin e 0.6 propolis extract 0.1 chamomile extract 0.15 lemon essential oil 0.4 lavender essential oil 0.4 rosewood essential oil 0.2 Soowit Orange Essential Oil 0.45

It was confirmed that when 1% by weight of American mealworm oil was added during soap preparation, there was no insect-specific scent and the soap materials were well mixed.

In addition, as a result of evaluating the quality characteristics of the prepared soap, the weight was measured to be 113.18 to 122.96 g, and the dry weight was measured to be 66.50 to 70.53 g.

In addition, the moisture content was measured to be 39.30 to 42.76%, and the pH was measured to be 9.61 to 9.94.

division acne trouble whitening elasticity moisturizing and soothing Weight (g) 116.30±1.88 119.57±3.39 118.24±1.44 dry weight (g) 67.17±0.67 70.18±0.35 68.20±0.61 moisture (%) 42.09±0.67 39.59±0.29 41.24±0.59 pH 9.87±0.07 9.69±0.08 9.74±0.08

Claims (8)

An antibacterial composition comprising the oil of American mealworm ( Zophobas morio ) larvae. [Claim 2] The composition for antibacterial according to claim 1, wherein the larvae of the American mealworm are larvae 2.5 to 3.5 months after hatching from eggs. In claim 1,
The composition is Staphylococcus aureus ), Pseudomonas aeruginosa ) and Propionibacterium acnes Antibacterial composition, characterized in that it has an antibacterial effect against one or more strains selected from the group consisting of. In claim 1,
The antibacterial composition is one type of use selected from the group consisting of cosmetics, skin cleaners, hair cleaners, vaginal cleaners, bathroom cleaners, mouthwashes, kitchen cleaners, cosmetic preservatives, food preservatives, pharmaceutical preservatives, food additives and feed additives. Antibacterial composition, characterized in that used. An antibacterial cosmetic composition comprising the oil of the American mealworm ( Zophobas morio ) larvae. Antibacterial soap containing the oil of Zophobas morio larvae. The antibacterial soap of claim 6, wherein the oil of the American mealworm larvae is included in 0.1 to 5% of the total composition. The method of claim 6, wherein the soap contains 36 to 57 wt% of a sodium salt of palm oil or palm oil fatty acid, 4 to 8 wt% of sodium lauryl sulfate, 25 to 30 wt% of glycerin, 5 to 9 wt% of sucrose, 0.5 to 1 wt% of shea butter Weight%, 0.5 to 1% by weight of camellia oil, 0.1% by weight of titanium dioxide, 0.1 to 0.2% by weight of Centella asiatica extract and 0.6% by weight of vitamin E, antibacterial soap.

Images