KR20210065111A - 히드라진 화합물의 제조를 위한 합성 방법 - Google Patents

히드라진 화합물의 제조를 위한 합성 방법 Download PDF

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Publication number
KR20210065111A
KR20210065111A KR1020217008902A KR20217008902A KR20210065111A KR 20210065111 A KR20210065111 A KR 20210065111A KR 1020217008902 A KR1020217008902 A KR 1020217008902A KR 20217008902 A KR20217008902 A KR 20217008902A KR 20210065111 A KR20210065111 A KR 20210065111A
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KR
South Korea
Prior art keywords
compound
nitrite
sulfite
salt
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
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KR1020217008902A
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English (en)
Korean (ko)
Inventor
윤쫑 리
시아오빈 지앙
니크 요하네스 론데
카르먼 라위스
제롬 도베르뉴
Original Assignee
메레오 바이오파마 1 리미티드
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Application filed by 메레오 바이오파마 1 리미티드 filed Critical 메레오 바이오파마 1 리미티드
Publication of KR20210065111A publication Critical patent/KR20210065111A/ko
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C241/00—Preparation of compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C241/02—Preparation of hydrazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/10—Hydrazines
    • C07C243/22—Hydrazines having nitrogen atoms of hydrazine groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/56—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and doubly-bound oxygen atoms bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020217008902A 2018-09-26 2019-09-26 히드라진 화합물의 제조를 위한 합성 방법 Ceased KR20210065111A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1815696.8A GB201815696D0 (en) 2018-09-26 2018-09-26 Synthetic method
GB1815696.8 2018-09-26
PCT/GB2019/052719 WO2020065324A1 (en) 2018-09-26 2019-09-26 Synthetic method for the preparation of an hydrazine compound

Publications (1)

Publication Number Publication Date
KR20210065111A true KR20210065111A (ko) 2021-06-03

Family

ID=64024292

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020217008902A Ceased KR20210065111A (ko) 2018-09-26 2019-09-26 히드라진 화합물의 제조를 위한 합성 방법

Country Status (12)

Country Link
US (1) US20210340108A1 (https=)
EP (1) EP3856711B1 (https=)
JP (1) JP2022502415A (https=)
KR (1) KR20210065111A (https=)
CN (1) CN112839923A (https=)
AU (1) AU2019349863A1 (https=)
CA (1) CA3112998A1 (https=)
DK (1) DK3856711T3 (https=)
ES (1) ES2933568T3 (https=)
GB (1) GB201815696D0 (https=)
IL (1) IL281637A (https=)
WO (1) WO2020065324A1 (https=)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2732967B1 (fr) * 1995-04-11 1997-07-04 Sanofi Sa 1-phenylpyrazole-3-carboxamides substitues, actifs sur la neurotensine, leur preparation, les compositions pharmaceutiques en contenant
PL2298743T3 (pl) 2003-06-26 2013-02-28 Novartis Ag Inhibitory kinaz P38 na bazie 5-członowych heterocykli
CN1326029C (zh) * 2003-07-10 2007-07-11 富士施乐株式会社 印刷装置、印刷指示装置、印刷处理系统及印刷处理方法
US7485657B2 (en) * 2004-05-12 2009-02-03 Boehringer Ingelheim Pharmaceuticals, Inc. Anti-cytokine heterocyclic compounds
AU2008281594A1 (en) * 2007-08-02 2009-02-05 Generics [Uk] Limited Novel process
WO2009088025A1 (ja) * 2008-01-10 2009-07-16 Hokko Chemical Industry Co., Ltd. フェニルトリアゾリノン類の製造法
JP5602387B2 (ja) * 2008-05-02 2014-10-08 キヤノン株式会社 インクジェット用インク、インクジェット記録方法、インクカートリッジ、記録ユニット、及びインクジェット記録装置
CN102964270B (zh) * 2012-11-21 2015-01-07 合肥星宇化学有限责任公司 一种亚硫酸钠还原重氮盐合成肼的方法
JP2016204436A (ja) * 2015-04-17 2016-12-08 日本化薬株式会社 水溶性アゾ化合物又はその塩、インク組成物及び着色体
WO2018059533A1 (zh) * 2016-09-29 2018-04-05 南京明德新药研发股份有限公司 p38αMAPK激酶抑制剂及其制备方法和应用

Also Published As

Publication number Publication date
DK3856711T3 (da) 2022-12-12
IL281637A (en) 2021-05-31
GB201815696D0 (en) 2018-11-07
AU2019349863A1 (en) 2021-04-15
CA3112998A1 (en) 2020-04-02
JP2022502415A (ja) 2022-01-11
EP3856711B1 (en) 2022-11-16
ES2933568T3 (es) 2023-02-10
US20210340108A1 (en) 2021-11-04
WO2020065324A1 (en) 2020-04-02
EP3856711A1 (en) 2021-08-04
CN112839923A (zh) 2021-05-25

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