KR20200130324A - Cd83-결합 키메라 항원 수용체 - Google Patents

Cd83-결합 키메라 항원 수용체 Download PDF

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KR20200130324A
KR20200130324A KR1020207027148A KR20207027148A KR20200130324A KR 20200130324 A KR20200130324 A KR 20200130324A KR 1020207027148 A KR1020207027148 A KR 1020207027148A KR 20207027148 A KR20207027148 A KR 20207027148A KR 20200130324 A KR20200130324 A KR 20200130324A
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마르코 다빌라
브라이언 벳츠
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에이치 리 모피트 캔서 센터 앤드 리서어치 인스티튜트 아이엔씨
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
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    • A61K40/42—Cancer antigens
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
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    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
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KR1020207027148A 2018-02-23 2019-02-22 Cd83-결합 키메라 항원 수용체 Ceased KR20200130324A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862634435P 2018-02-23 2018-02-23
US62/634,435 2018-02-23
US201862677783P 2018-05-30 2018-05-30
US62/677,783 2018-05-30
PCT/US2019/019065 WO2019165156A1 (en) 2018-02-23 2019-02-22 Cd83-binding chimeric antigen receptors

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KR20200130324A true KR20200130324A (ko) 2020-11-18

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KR1020207027148A Ceased KR20200130324A (ko) 2018-02-23 2019-02-22 Cd83-결합 키메라 항원 수용체

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US (1) US12492254B2 (https=)
EP (1) EP3755722A4 (https=)
JP (1) JP7358369B2 (https=)
KR (1) KR20200130324A (https=)
CN (1) CN112004832A (https=)
AU (1) AU2019226101A1 (https=)
BR (1) BR112020017015A2 (https=)
IL (1) IL276836A (https=)
MA (1) MA51917A (https=)
MX (1) MX2020008803A (https=)
PH (1) PH12020500632A1 (https=)
SG (1) SG11202007755YA (https=)
WO (1) WO2019165156A1 (https=)
ZA (1) ZA202005837B (https=)

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AU2020334893A1 (en) * 2019-08-16 2022-02-24 H. Lee Moffitt Cancer Center And Research Institute Inc. Chimeric antigen receptors for treating myeloid malignancies
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WO2019165156A1 (en) 2019-08-29
MX2020008803A (es) 2021-01-15
JP7358369B2 (ja) 2023-10-10
PH12020500632A1 (en) 2021-05-10
AU2019226101A1 (en) 2020-09-17
EP3755722A1 (en) 2020-12-30
MA51917A (fr) 2021-06-02
US12492254B2 (en) 2025-12-09
JP2021513857A (ja) 2021-06-03
SG11202007755YA (en) 2020-09-29
CA3092220A1 (en) 2019-08-29
BR112020017015A2 (pt) 2020-12-15
CN112004832A (zh) 2020-11-27
IL276836A (en) 2020-10-29
US20210032336A1 (en) 2021-02-04
ZA202005837B (en) 2023-02-22
EP3755722A4 (en) 2021-11-24

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