KR20200116546A - 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료 - Google Patents

태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료 Download PDF

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KR20200116546A
KR20200116546A KR1020207027962A KR20207027962A KR20200116546A KR 20200116546 A KR20200116546 A KR 20200116546A KR 1020207027962 A KR1020207027962 A KR 1020207027962A KR 20207027962 A KR20207027962 A KR 20207027962A KR 20200116546 A KR20200116546 A KR 20200116546A
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cells
placental
isolated
stem cells
population
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Korean (ko)
Inventor
스튜어트 애보트
제임스 더블유. 에딩거
알렉잔다르 프란키
블라디미르 얀코비치
알렉산드르 카플루노브스키
크리스텐 라바쪼
에릭 로우
비타오 리앙
로버트 제이. 하리리
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안트로제네시스 코포레이션
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Priority to KR1020217026195A priority Critical patent/KR20210107144A/ko
Publication of KR20200116546A publication Critical patent/KR20200116546A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Reproductive Health (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Urology & Nephrology (AREA)
  • Otolaryngology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
KR1020207027962A 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료 Ceased KR20200116546A (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020217026195A KR20210107144A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201061424559P 2010-12-17 2010-12-17
US61/424,559 2010-12-17
PCT/US2011/065170 WO2012083024A1 (en) 2010-12-17 2011-12-15 Treatment of spinal cord injury and traumatic brain injury using placental stem cells

Related Parent Applications (1)

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KR1020197021890A Division KR20190090882A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료

Related Child Applications (1)

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KR1020217026195A Division KR20210107144A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료

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KR20200116546A true KR20200116546A (ko) 2020-10-12

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Family Applications (7)

Application Number Title Priority Date Filing Date
KR1020207027962A Ceased KR20200116546A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료
KR1020137018583A Ceased KR20130128437A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료
KR1020187024573A Ceased KR20180100251A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료
KR1020227023531A Ceased KR20220103812A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료
KR1020217026195A Ceased KR20210107144A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료
KR1020237025647A Ceased KR20230116964A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌손상의 치료
KR1020197021890A Ceased KR20190090882A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료

Family Applications After (6)

Application Number Title Priority Date Filing Date
KR1020137018583A Ceased KR20130128437A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료
KR1020187024573A Ceased KR20180100251A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료
KR1020227023531A Ceased KR20220103812A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료
KR1020217026195A Ceased KR20210107144A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료
KR1020237025647A Ceased KR20230116964A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌손상의 치료
KR1020197021890A Ceased KR20190090882A (ko) 2010-12-17 2011-12-15 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료

Country Status (9)

Country Link
US (1) US20120156230A1 (enExample)
EP (1) EP2651451A4 (enExample)
JP (1) JP2014507390A (enExample)
KR (7) KR20200116546A (enExample)
CN (1) CN103501822A (enExample)
AU (1) AU2011343739A1 (enExample)
CA (1) CA2821818A1 (enExample)
MX (1) MX2013006595A (enExample)
WO (1) WO2012083024A1 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6204976B2 (ja) * 2012-05-16 2017-09-27 ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company 多能性幹細胞由来の細胞培養物からニューロンを単離するための細胞表面特性
JP2015521630A (ja) * 2012-06-26 2015-07-30 ラスティー プロパティー ホールディングス プロプライエタリー リミテッド 頭痛の頻度および/または重症度を下げるための組成物および方法
WO2014022427A1 (en) * 2012-08-02 2014-02-06 Bioaxone Biosciences Inc. Inhibition of rho and or rock and cell transplantation
EP2994147A4 (en) * 2013-05-10 2017-03-08 Cell-Innovations IP Pty Ltd Compositions and methods for the treatment of tinnitus
WO2015023901A1 (en) * 2013-08-15 2015-02-19 The Regents Of The University Of California Placenta-derived multipotent stem cells
DK3157548T3 (da) 2014-06-18 2021-09-06 Csl Behring Gmbh Terapi anvendelse af en faktor xii-inhibitor i en neurotraumatisk sygdom
US10493105B2 (en) * 2014-09-11 2019-12-03 Taiwan Mitochondrion Applied Technology Co., Ltd Isolated adipose-derived mesenchymal stem cells treated with angelica extract or butylidenephthalide, and wherein the cells have an increased mitochondrial membrane potential and a decreased level of IL-8, and methods for treating parkinson's disease
GB201518263D0 (en) * 2015-10-15 2015-12-02 Oxford Bioelectronics Ltd Method
EP3423070B1 (en) * 2016-03-03 2022-05-04 Henry Ford Health System 3-d collagen scaffold-generated exosomes and uses thereof
EA201991371A1 (ru) * 2016-12-05 2019-12-30 Селулэрити, Инк. Лечение лимфедемы и связанных состояний с использованием плацентарных адгезивных клеток
WO2018198012A1 (en) * 2017-04-24 2018-11-01 Pluristem Ltd. Methods and compositions for treating neurological disorders
US20180322956A1 (en) * 2017-05-05 2018-11-08 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Time Window-Based Platform for the Rapid Stratification of Blunt Trauma Patients into Distinct Outcome Cohorts
WO2018222723A1 (en) 2017-05-30 2018-12-06 Vertex Pharmaceuticals Incorporated C3 fusion protein and methods of making and using thereof
CN107227521B (zh) * 2017-08-09 2023-03-14 青岛金汇丰机械有限公司 一种五轴毛纺粗纱机
KR20190048894A (ko) 2017-10-31 2019-05-09 경상대학교산학협력단 Jnk 활성 억제제를 유효성분으로 포함하는 퇴행성 신경질환의 예방 또는 치료용 약학적 조성물
CN108413478A (zh) * 2018-02-11 2018-08-17 广东美的环境电器制造有限公司 一种控制方法、装置及计算机可读存储介质
KR102070403B1 (ko) 2019-09-06 2020-01-28 경상대학교 산학협력단 Jnk 활성 억제제를 유효성분으로 포함하는 외상성 뇌손상의 치료용 약학적 조성물
CN114561355B (zh) * 2022-01-23 2023-04-11 四川大学华西医院 一种脊髓瘢痕组织细胞急性快速分离方法
CN117274869B (zh) * 2023-09-25 2024-03-26 北方工业大学 一种基于形变场提取的细胞形变动态分类方法及系统

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7311905B2 (en) * 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
US20080152629A1 (en) * 2000-12-06 2008-06-26 James Edinger Placental stem cell populations
KR20180105266A (ko) * 2005-12-29 2018-09-27 안트로제네시스 코포레이션 태반 줄기 세포 집단
US20120269774A1 (en) * 2006-09-21 2012-10-25 Medistem Laboratories, Inc Allogeneic stem cell transplants in non-conditioned recipients
CN103356710A (zh) * 2007-02-12 2013-10-23 人类起源公司 利用胎盘干细胞治疗炎性疾病
US20090214484A1 (en) * 2008-02-22 2009-08-27 Nikolay Mironov Stem cell therapy for the treatment of central nervous system disorders
CA2734237C (en) * 2008-08-20 2019-07-02 Anthrogenesis Corporation Treatment of stroke using isolated placental cells
WO2010059828A1 (en) * 2008-11-19 2010-05-27 Anthrogenesis Corporation Amnion derived adherent cells

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Publication number Publication date
WO2012083024A1 (en) 2012-06-21
KR20230116964A (ko) 2023-08-04
KR20130128437A (ko) 2013-11-26
MX2013006595A (es) 2014-04-07
KR20180100251A (ko) 2018-09-07
JP2014507390A (ja) 2014-03-27
KR20190090882A (ko) 2019-08-02
KR20210107144A (ko) 2021-08-31
CA2821818A1 (en) 2012-06-21
CN103501822A (zh) 2014-01-08
US20120156230A1 (en) 2012-06-21
AU2011343739A1 (en) 2013-05-02
KR20220103812A (ko) 2022-07-22
EP2651451A1 (en) 2013-10-23
EP2651451A4 (en) 2014-05-21
WO2012083024A8 (en) 2013-08-01

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