EA201991371A1 - Лечение лимфедемы и связанных состояний с использованием плацентарных адгезивных клеток - Google Patents

Лечение лимфедемы и связанных состояний с использованием плацентарных адгезивных клеток

Info

Publication number
EA201991371A1
EA201991371A1 EA201991371A EA201991371A EA201991371A1 EA 201991371 A1 EA201991371 A1 EA 201991371A1 EA 201991371 A EA201991371 A EA 201991371A EA 201991371 A EA201991371 A EA 201991371A EA 201991371 A1 EA201991371 A1 EA 201991371A1
Authority
EA
Eurasian Patent Office
Prior art keywords
placental
lymphedema
treatment
related conditions
adhesive cells
Prior art date
Application number
EA201991371A
Other languages
English (en)
Inventor
Роберт Дж. Хэрири
Шуян ХЭ
Original Assignee
Селулэрити, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Селулэрити, Инк. filed Critical Селулэрити, Инк.
Publication of EA201991371A1 publication Critical patent/EA201991371A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/02—Atmosphere, e.g. low oxygen conditions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/02—Coculture with; Conditioned medium produced by embryonic cells
    • C12N2502/025—Coculture with; Conditioned medium produced by embryonic cells extra-embryonic cells, e.g. amniotic epithelium, placental cells, Wharton's jelly
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/28—Vascular endothelial cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Reproductive Health (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

В данном изобретении предлагаются способы применения прилипающих к пластику для культуры ткани плацентарных адгезивных клеток, например плацентарных стволовых клеток, называемых здесь плацентарными адгезивными клетками, для лечения лимфедемы и связанных с лимфедемой нарушений.
EA201991371A 2016-12-05 2017-12-06 Лечение лимфедемы и связанных состояний с использованием плацентарных адгезивных клеток EA201991371A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662430123P 2016-12-05 2016-12-05
PCT/US2017/064789 WO2018106742A1 (en) 2016-12-05 2017-12-06 Treatment of lymphedema and related conditions using placental adherent cells

Publications (1)

Publication Number Publication Date
EA201991371A1 true EA201991371A1 (ru) 2019-12-30

Family

ID=60972338

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201991371A EA201991371A1 (ru) 2016-12-05 2017-12-06 Лечение лимфедемы и связанных состояний с использованием плацентарных адгезивных клеток

Country Status (10)

Country Link
US (2) US20190314424A1 (ru)
EP (1) EP3548051A1 (ru)
JP (2) JP2020512970A (ru)
CN (1) CN110402147A (ru)
AU (1) AU2017373862A1 (ru)
BR (1) BR112019011561A2 (ru)
CA (1) CA3046078A1 (ru)
EA (1) EA201991371A1 (ru)
MX (1) MX2019006514A (ru)
WO (1) WO2018106742A1 (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020082051A1 (en) * 2018-10-19 2020-04-23 Regents Of The University Of Minnesota Transplant tolerance induction with carbodiimide treated tolerizing vaccine

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4798824A (en) 1985-10-03 1989-01-17 Wisconsin Alumni Research Foundation Perfusate for the preservation of organs
US5190556A (en) 1991-03-19 1993-03-02 O.B. Tech, Inc. Cord cutter sampler
US5552267A (en) 1992-04-03 1996-09-03 The Trustees Of Columbia University In The City Of New York Solution for prolonged organ preservation
US5372581A (en) 1993-07-21 1994-12-13 Minneapolis Children's Services Corporation Method and apparatus for placental blood collection
KR100619611B1 (ko) 1999-04-16 2006-09-01 더블유엠. 마쉬 라이스 유니버시티 작용화 폴리(프로필렌 푸마레이트) 및 폴리(프로필렌푸마레이트-코-에틸렌 글리콜
US6355699B1 (en) 1999-06-30 2002-03-12 Ethicon, Inc. Process for manufacturing biomedical foams
CA2678490A1 (en) 2000-12-06 2002-06-13 Robert J. Hariri Isolated placental perfusate and placental cells isolated therefrom
US7311905B2 (en) 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
JP2004528021A (ja) 2001-02-14 2004-09-16 アンスロジェネシス コーポレーション 分娩後の哺乳動物の胎盤、その使用およびそれに由来する胎盤幹細胞
KR101132545B1 (ko) 2001-02-14 2012-04-02 안트로제네시스 코포레이션 산후 포유류의 태반, 이의 용도 및 태반 줄기세포
US20030187515A1 (en) 2002-03-26 2003-10-02 Hariri Robert J. Collagen biofabric and methods of preparing and using the collagen biofabric
US7255729B2 (en) 2003-05-30 2007-08-14 Noritake Co., Limited Porous cylindrical-body module, structure for supporting porous cylindrical bodies, and method for fastening a supporting member
US7147626B2 (en) 2004-09-23 2006-12-12 Celgene Corporation Cord blood and placenta collection kit
ES2708933T3 (es) 2005-12-29 2019-04-12 Celularity Inc Poblaciones de células madre placentarias
ZA200804717B (en) 2005-12-29 2010-02-24 Anthrogenesis Corp Improved composition for collecting and preserving a placental stem cells and methods of using the composition
KR20190050867A (ko) * 2007-09-26 2019-05-13 안트로제네시스 코포레이션 인간 태반 관류액으로부터의 혈관형성 세포
AU2013203479B2 (en) * 2010-04-07 2016-05-19 Celularity Inc. Angiogenesis using placental stem cells
TW201138792A (en) * 2010-04-08 2011-11-16 Anthrogenesis Corp Treatment of sarcoidosis using placental stem cells
KR20180100251A (ko) * 2010-12-17 2018-09-07 안트로제네시스 코포레이션 태반 줄기 세포를 이용하는 척수 손상 및 외상성 뇌 손상의 치료
WO2012092480A1 (en) * 2010-12-30 2012-07-05 Anthirogenesis Corporation Compositions comprising amnion derived adherent cells and platelet-rich plasma
JP5750951B2 (ja) 2011-03-14 2015-07-22 富士通株式会社 エッチングする方法及びエッチング装置
ITTO20111183A1 (it) * 2011-12-21 2013-06-22 Univ Degli Studi Torino Mezzo condizionato ottenuto da cellule staminali mesenchimali placentari e suo uso nel trattamento terapeutico della preeclampsia
EP2676668A1 (en) * 2012-06-22 2013-12-25 Biologische Heilmittel Heel GmbH Composition for treating lymphedema
JP6371286B2 (ja) * 2012-09-04 2018-08-08 プルリステム リミテッド 子癇前症の予防及び治療方法
EP2968420B1 (en) * 2013-03-14 2018-09-05 Celularity, Inc. Use of placental stem cells in treatment of acute kidney injury

Also Published As

Publication number Publication date
EP3548051A1 (en) 2019-10-09
BR112019011561A2 (pt) 2019-10-15
US20190314424A1 (en) 2019-10-17
CA3046078A1 (en) 2018-06-14
WO2018106742A1 (en) 2018-06-14
AU2017373862A1 (en) 2019-06-27
CN110402147A (zh) 2019-11-01
MX2019006514A (es) 2019-10-30
JP2020512970A (ja) 2020-04-30
US20230302058A1 (en) 2023-09-28
JP2023017816A (ja) 2023-02-07

Similar Documents

Publication Publication Date Title
MX2018011216A (es) Moléculas pequeñas contra cereblon para mejorar la función efectora de los linfocitos t.
EA201891202A1 (ru) Композиции, содержащие бактериальные штаммы
MX2020003702A (es) Ciclopropilaminas como inhibidores de desmetilasa especifica de lisina 1 (lsd1).
EA201891201A1 (ru) Композиции, содержащие бактериальные штаммы
EA201891539A1 (ru) Соединения, ингибирующие металлоферменты
EA201890050A1 (ru) Композиции, содержащие бактериальные штаммы
EA201890049A1 (ru) Композиции, содержащие бактериальные штаммы
EA201791867A1 (ru) Бициклические гетероциклы как ингибиторы fgfr4
BR112017024384A2 (pt) bactérias modificadas para reduzir hiperfenilalaninemia
EA201792205A1 (ru) Гетероциклические соединения как ингибиторы lsd1
EA201790273A1 (ru) Флагеллиновые композиции и их применение
MX2020005567A (es) Metodos de tratamiento con asparaginasa.
SG10201908028SA (en) Cyclopropylamines as lsd1 inhibitors
EA201500943A1 (ru) Составы для мобилизации, хоуминга, размножения и дифференцировки стволовых клеток и способы применения составов
EA201691447A1 (ru) 2-амино-3,5,5-трифтор-3,4,5,6-тетрагидропиридины в качестве ингибиторов bace1 для лечения болезни альцгеймера
EA201690007A1 (ru) Соединения, ингибирующие металлоферменты
EP4268860A3 (en) Compositions, devices, kits and methods for attaching stent-containing medical devices to tissue
EA201890185A1 (ru) Способы лечения опосредованных гепсидином нарушений
EA202091731A1 (ru) Ингибиторы аутотаксина и их применения
MX2018012902A (es) Composiciones y métodos para el tratamiento de trastornos de almacenamiento lisosomal y trastornos caracterizados por disfunción lisosomal.
EA201891468A1 (ru) Композиции и способы для снижения экспрессии tau
MX2022012386A (es) Compuestos inhibidores de metaloenzimas.
EA201790565A1 (ru) Композиции и способы для лечения предраковых поражений кожи
DK3189844T3 (da) Pluripotent stamcelle til behandling af diabetisk hudsår
MX2022004373A (es) Celulas madre modificadas y metodos de uso de las mismas.