KR20200078497A - 신규의 t-세포 수용체 - Google Patents

신규의 t-세포 수용체 Download PDF

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Publication number
KR20200078497A
KR20200078497A KR1020207011102A KR20207011102A KR20200078497A KR 20200078497 A KR20200078497 A KR 20200078497A KR 1020207011102 A KR1020207011102 A KR 1020207011102A KR 20207011102 A KR20207011102 A KR 20207011102A KR 20200078497 A KR20200078497 A KR 20200078497A
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tcr
cell
cells
cancer
clone
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KR1020207011102A
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English (en)
Korean (ko)
Inventor
앤드류 세웰
게리 돌튼
Original Assignee
유니버시티 칼리지 카디프 컨설턴츠 리미티드
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Publication of KR20200078497A publication Critical patent/KR20200078497A/ko
Ceased legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/30Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/32T-cell receptors [TCR]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/15011Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15041Use of virus, viral particle or viral elements as a vector
    • C12N2740/15043Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Hematology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020207011102A 2017-10-26 2018-10-22 신규의 t-세포 수용체 Ceased KR20200078497A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB1717578.7 2017-10-26
GBGB1717578.7A GB201717578D0 (en) 2017-10-26 2017-10-26 Novel T-cell receptor
GBGB1806155.6A GB201806155D0 (en) 2017-10-26 2018-04-16 Novel t-cell receptor
GB1806155.6 2018-04-16
PCT/GB2018/053045 WO2019081902A1 (en) 2017-10-26 2018-10-22 NEW LYMPHOCYTE RECEPTOR T

Publications (1)

Publication Number Publication Date
KR20200078497A true KR20200078497A (ko) 2020-07-01

Family

ID=60580240

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020207011102A Ceased KR20200078497A (ko) 2017-10-26 2018-10-22 신규의 t-세포 수용체

Country Status (17)

Country Link
US (2) US11725039B2 (enExample)
EP (2) EP4039700A1 (enExample)
JP (1) JP7289311B2 (enExample)
KR (1) KR20200078497A (enExample)
CN (1) CN111278855B (enExample)
AU (2) AU2018356944A1 (enExample)
BR (1) BR112020007880A2 (enExample)
CA (1) CA3077635A1 (enExample)
DK (1) DK3700925T3 (enExample)
EA (1) EA202091015A1 (enExample)
ES (1) ES2907819T3 (enExample)
GB (2) GB201717578D0 (enExample)
IL (1) IL274025A (enExample)
MX (1) MX2020004334A (enExample)
PL (1) PL3700925T3 (enExample)
SG (1) SG11202002537WA (enExample)
WO (1) WO2019081902A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023106894A1 (ko) * 2021-12-10 2023-06-15 주식회사 유틸렉스 Mr1 제한적 panck t 세포 및 이의 제조방법

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201717578D0 (en) * 2017-10-26 2017-12-13 Univ College Cardiff Consultants Ltd Novel T-cell receptor
CA3163023A1 (en) * 2020-01-09 2021-07-15 Olivier Lantz Multispecific antibodies that bind both mait and tumor cells
CA3163041A1 (en) * 2020-01-16 2021-07-22 Gennaro De Libero Mr1 ligands and pharmaceutical compositions for immunomodulation
KR20210153539A (ko) * 2020-06-10 2021-12-17 주식회사 유틸렉스 Mr1에 결합하는 t-세포 수용체 및 이의 용도
IL302481A (en) * 2020-11-04 2023-06-01 Fate Therapeutics Inc Multiplexed engineered ipsc and immune effector cells targeting solid tumors
WO2022118043A1 (en) 2020-12-03 2022-06-09 Enara Bio Limited Novel protein-ligand complex
WO2022248881A1 (en) 2021-05-28 2022-12-01 Enara Bio Limited Novel protein-ligand complex
JP2024525727A (ja) 2021-07-14 2024-07-12 2セブンティ バイオ インコーポレイテッド 抗体由来の結合ドメインに融合した操作されたt細胞受容体
WO2023002204A1 (en) 2021-07-21 2023-01-26 Enara Bio Limited T-cell receptor
EP4472742A1 (en) 2022-02-03 2024-12-11 University College Cardiff Consultants Limited Novel t-cell receptor
KR20250008809A (ko) 2022-04-08 2025-01-15 리제너론 파마슈티칼스 인코포레이티드 다분할 수용체 및 신호전달 복합체

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI777196B (zh) * 2013-08-05 2022-09-11 德商伊瑪提克斯生物科技有限公司 新穎肽類,細胞及其用於治療多種腫瘤的用途,其製造方法及包含其等之醫藥組成物(五)
EP3572510B1 (en) * 2013-11-21 2022-09-21 Repertoire Genesis Incorporation T cell receptor and b cell receptor repertoire analysis system, and use of same in treatment and diagnosis
JP7233103B2 (ja) * 2017-03-07 2023-03-06 ウニヴェルズィテート バーゼル 癌免疫療法用mr1制限t細胞受容体
GB201717578D0 (en) * 2017-10-26 2017-12-13 Univ College Cardiff Consultants Ltd Novel T-cell receptor

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023106894A1 (ko) * 2021-12-10 2023-06-15 주식회사 유틸렉스 Mr1 제한적 panck t 세포 및 이의 제조방법

Also Published As

Publication number Publication date
US11078252B2 (en) 2021-08-03
EA202091015A1 (ru) 2020-07-17
GB201717578D0 (en) 2017-12-13
JP2021500406A (ja) 2021-01-07
EP3700925A1 (en) 2020-09-02
EP3700925B1 (en) 2021-12-29
GB201806155D0 (en) 2018-05-30
WO2019081902A1 (en) 2019-05-02
CN111278855B (zh) 2024-04-02
EP4039700A1 (en) 2022-08-10
SG11202002537WA (en) 2020-05-28
DK3700925T3 (en) 2022-04-04
EP3700925B8 (en) 2022-02-16
PL3700925T3 (pl) 2022-05-02
IL274025A (en) 2020-06-30
AU2024202735A1 (en) 2024-05-30
ES2907819T3 (es) 2022-04-26
BR112020007880A2 (pt) 2020-10-27
MX2020004334A (es) 2020-08-03
US20210147506A1 (en) 2021-05-20
CA3077635A1 (en) 2019-05-02
AU2018356944A1 (en) 2020-04-16
JP7289311B2 (ja) 2023-06-09
CN111278855A (zh) 2020-06-12
US20200369742A1 (en) 2020-11-26
US11725039B2 (en) 2023-08-15

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