CA3077635A1 - Novel t-cell receptor - Google Patents
Novel t-cell receptor Download PDFInfo
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- CA3077635A1 CA3077635A1 CA3077635A CA3077635A CA3077635A1 CA 3077635 A1 CA3077635 A1 CA 3077635A1 CA 3077635 A CA3077635 A CA 3077635A CA 3077635 A CA3077635 A CA 3077635A CA 3077635 A1 CA3077635 A1 CA 3077635A1
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Classifications
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- C—CHEMISTRY; METALLURGY
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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- A61K40/00—Cellular immunotherapy
- A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
- A61K40/32—T-cell receptors [TCR]
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- A—HUMAN NECESSITIES
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15041—Use of virus, viral particle or viral elements as a vector
- C12N2740/15043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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| GB1717578.7 | 2017-10-26 | ||
| GB1806155.6 | 2018-04-16 | ||
| GBGB1806155.6A GB201806155D0 (en) | 2017-10-26 | 2018-04-16 | Novel t-cell receptor |
| PCT/GB2018/053045 WO2019081902A1 (en) | 2017-10-26 | 2018-10-22 | NEW LYMPHOCYTE RECEPTOR T |
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| GB201717578D0 (en) * | 2017-10-26 | 2017-12-13 | Univ College Cardiff Consultants Ltd | Novel T-cell receptor |
| BR112022013633A2 (pt) * | 2020-01-09 | 2022-09-13 | Biomunex Pharmaceuticals | Anticorpos multiespecíficos que ligam tanto células mait quanto tumorais |
| CN115943307A (zh) * | 2020-01-16 | 2023-04-07 | 巴塞尔大学 | 用于免疫调节的mr1配体和药物组合物 |
| WO2021250511A1 (ko) * | 2020-06-10 | 2021-12-16 | 주식회사 유틸렉스 | Mr1에 결합하는 t-세포 수용체 및 이의 용도 |
| US20230381235A1 (en) * | 2020-11-04 | 2023-11-30 | Fate Therapeutics, Inc. | Multiplexed engineered ipscs and immune effector cells targeting solid tumors |
| WO2022118043A1 (en) | 2020-12-03 | 2022-06-09 | Enara Bio Limited | Novel protein-ligand complex |
| WO2022248881A1 (en) | 2021-05-28 | 2022-12-01 | Enara Bio Limited | Novel protein-ligand complex |
| IL309957A (en) | 2021-07-14 | 2024-03-01 | 2Seventy Bio Inc | Engineered t cell receptors fused to binding domains from antibodies |
| WO2023002204A1 (en) | 2021-07-21 | 2023-01-26 | Enara Bio Limited | T-cell receptor |
| KR20230088292A (ko) * | 2021-12-10 | 2023-06-19 | 주식회사 유틸렉스 | MR1 제한적 Panck T 세포 및 이의 제조방법 |
| WO2023148494A1 (en) | 2022-02-03 | 2023-08-10 | University College Cardiff Consultants Limited | Novel t-cell receptor |
| KR20250008809A (ko) | 2022-04-08 | 2025-01-15 | 리제너론 파마슈티칼스 인코포레이티드 | 다분할 수용체 및 신호전달 복합체 |
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| TWI819228B (zh) * | 2013-08-05 | 2023-10-21 | 德商伊瑪提克斯生物科技有限公司 | 新穎肽類，細胞及其用於治療多種腫瘤的用途，其製造方法及包含其等之醫藥組成物（八） |
| JP6164759B2 (ja) | 2013-11-21 | 2017-07-19 | Ｒｅｐｅｒｔｏｉｒｅ Ｇｅｎｅｓｉｓ株式会社 | Ｔ細胞受容体およびｂ細胞受容体レパトアの解析システムならびにその治療および診断への利用 |
| CN110462024B (zh) * | 2017-03-07 | 2024-08-09 | 巴塞尔大学 | 用于癌症免疫疗法的mr1限制性t细胞受体 |
| GB201717578D0 (en) * | 2017-10-26 | 2017-12-13 | Univ College Cardiff Consultants Ltd | Novel T-cell receptor |
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| US11078252B2 (en) | 2021-08-03 |
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| JP2021500406A (ja) | 2021-01-07 |
| CN111278855B (zh) | 2024-04-02 |
| GB201717578D0 (en) | 2017-12-13 |
| EP3700925B8 (en) | 2022-02-16 |
| US20200369742A1 (en) | 2020-11-26 |
| ES2907819T3 (es) | 2022-04-26 |
| JP7289311B2 (ja) | 2023-06-09 |
| EP3700925A1 (en) | 2020-09-02 |
| EP3700925B1 (en) | 2021-12-29 |
| PL3700925T3 (pl) | 2022-05-02 |
| IL274025A (en) | 2020-06-30 |
| US11725039B2 (en) | 2023-08-15 |
| DK3700925T3 (en) | 2022-04-04 |
| SG11202002537WA (en) | 2020-05-28 |
| AU2018356944A1 (en) | 2020-04-16 |
| US20210147506A1 (en) | 2021-05-20 |
| KR20200078497A (ko) | 2020-07-01 |
| MX2020004334A (es) | 2020-08-03 |
| GB201806155D0 (en) | 2018-05-30 |
| WO2019081902A1 (en) | 2019-05-02 |
| AU2024202735A1 (en) | 2024-05-30 |
| EA202091015A1 (ru) | 2020-07-17 |
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